PubHawk
Sci Transl Med November 2009 PMID 20368178

The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice.

Peter J Turnbaugh, Vanessa K Ridaura, Jeremiah J Faith, Federico E Rey, Rob Knight, Jeffrey I Gordon

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Mentions

12
Peak: 1 in Sep 2015
across 4 sources since Sep 2015

Extended reach

3,826
potential audience

Total likes

19

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1,134

Mentions per month

Sep 2015 – Dec 2025

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AI synopsis

What people are saying

The discussions reflect a general acknowledgment of the article's findings, with remarks like 'everything old is 'new' again,' suggesting a recognition of the ongoing relevance of microbiome research. The tone is conversational and somewhat casual, indicating a moderate level of interest and engagement without deep technical analysis.

AgreementModerate agreement

Most discussions recognize the relevance of the study, with some agree ing that it confirms well-known links between diet and microbiome changes.

InterestModerate interest

Posts show moderate curiosity, as participants acknowledge the significance but do not delve deeply into technical details.

EngagementModerate engagement

Discussions include some references to the study's methods and implications, indicating a decent level of engagement.

ImpactModerate impact

While conversations highlight the importance of diet-microbiome interactions, they mostly situate the study within existing research, suggesting a moderate impact perception.

Abstract in brief

  • The study used germ-free mice colonized with human gut microbes to create a stable, representative model of the human gut, allowing researchers to examine how diet influences microbiome structure, function, and gene expression.
  • Switching the mice's diet from low-fat plant-based to high-fat, high-sugar Western diet caused rapid and significant changes in the microbiome, affecting bacterial diversity, metabolic pathways, and gene activity within just one day.
  • The research found that the composition of gut microbiota depends on both colonization history and diet, and that alterations in diet can swiftly modify microbial communities, which can also influence host traits like increased fat accumulation that can be transferred through microbiota transplantation.]
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Alban Gaultier
@GaultierAlban · X

@LabWaggoner @Nature everything old is "new" again https://t.co/0Ruzj1QfBI

Apr 30, 2025 · 1 like · 2,602 followers View post →

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Alban Gaultier
@GaultierAlban · X

@LabWaggoner @Nature everything old is "new" again https://t.co/0Ruzj1QfBI

Apr 30, 2025 · 1 like · 2,602 followers View post →
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