November 2009 PMID 20368179

Follistatin gene delivery enhances muscle growth and strength in nonhuman primates.

Janaiah Kota, Chalonda R Handy, Amanda M Haidet, Chrystal L Montgomery, Amy Eagle, Louise R Rodino-Klapac, Danielle Tucker, Christopher J Shilling, Walter R Therlfall, Christopher M Walker, Steven E Weisbrode, Paul M L Janssen, K Reed Clark, Zarife Sahenk, Jerry R Mendell

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Mentions

20
Peak: 10 in Feb 2024
across 4 sources since Oct 2023

Extended reach

669,297
potential audience

Total likes

1,781

Video views

57,246

Mentions per month

Oct 2023 – Jun 2024

Where it's discussed

  • X / Twitter12 posts
  • Facebook3 posts
  • Blogs3 articles
  • YouTube2 videos

AI synopsis

What people are saying

The discussions demonstrate a general curiosity about follistatin's benefits, referencing its effects on lifespan in mice and its popularity in fitness communities, with phrases like 'big scientific literature' and 'potentially used to treat human muscle degenerative diseases' indicating an awareness of its significance and future promise.

AgreementNeither agree nor disagree

Most posts show curiosity or mild approval, with some referencing additional literature or potential benefits, but few express strong agreement with the research outcomes.

InterestModerate interest

Discussions reflect a moderate level of interest, especially in connection to health benefits and longevity trends.

EngagementModerate engagement

Postings often mention related studies, suggest searching for more information, and reference societal implications, indicating active engagement.

ImpactModerate impact

The novelty and potential applications of the gene therapy could influence future research or treatment approaches, but the overall impact remains speculative at this stage.

Abstract in brief

  • Follistatin gene delivery can significantly increase muscle size and strength in nonhuman primates, specifically cynomolgus macaque monkeys, by injecting a specialized gene vector into their muscles.
  • The study found that this gene therapy approach was safe, showing no adverse effects on the muscles' structure or key organs over the long term.
  • These promising results in primates, along with previous success in mice, suggest that this method could potentially be used to treat human muscle degenerative diseases in the future.

Top posts

Most liked on X and Bluesky
Agingdoc
@agingdoc1 · X

Follistatin - why is this the new longevity trend?

Feb 13, 2024 · 33 likes · 5 shares · 40,973 followers View post →
Agingdoc
@agingdoc1 · X

Follistatin Gene Delivery Enhances Muscle Growth and Strength in Nonhuman Primates (2009) https://t.co/4bBlcPu0nC https://t.co/8by9vSjxjz

Feb 15, 2024 · 4 likes · 1 share · 43,636 followers View post →
Longevity for everyone
@Happy_Long_Life · X

@WilliamMegenney @bryan_johnson You can simply Google Follistatin gene therapy. Follistatin Gene Delivery Enhances Muscle Growth and Strength in Nonhuman Primates https://t.co/rrnoc7pnGn

Oct 2, 2023 · 3 likes · 125 followers View post →
Jog
@nomojo321 · X

@RokoMijic @Hatecraft333 Studies in mice actually showed a 32% increase in lifespan and reduced hair loss https://t.co/zC6arFtJji

Feb 14, 2024 · 2 likes · 65 followers View post →
The Longevist
@Dr_coachbear · X

RT @agingdoc1: Follistatin - why is this the new longevity trend?

Feb 13, 2024 · 5 shares · 516,304 followers View post →
Eleanor Sheekey
@EleanorSheekey · X

RT @agingdoc1: Follistatin - why is this the new longevity trend?

Feb 14, 2024 · 5 shares · 4,875 followers View post →

All mentions

Aleksandr Sviridov
@lex_sviridov · X

@BJones83560 @kingoff00ls Unfortunately, I have not had a chance to look into that in detail yet. @EleanorSheekey did a short review on reasons why people think follistatin might be beneficial for longevity: https://t.co/RvHaVxLilk

Apr 9, 2024 · 1,185 followers View post →
Agingdoc
@agingdoc1 · X

Follistatin Gene Delivery Enhances Muscle Growth and Strength in Nonhuman Primates (2009) https://t.co/4bBlcPu0nC https://t.co/8by9vSjxjz

Feb 15, 2024 · 4 likes · 1 share · 43,636 followers View post →
BEAST magazine
@beast_media_net · X

Follistatin - why is this the new longevity trend? https://t.co/D7ArK8Qrgh via @YouTube

Feb 15, 2024 · 1,199 followers View post →
Jog
@nomojo321 · X

@RokoMijic @Hatecraft333 Studies in mice actually showed a 32% increase in lifespan and reduced hair loss https://t.co/zC6arFtJji

Feb 14, 2024 · 2 likes · 65 followers View post →
Carles Villaplana
@carlesvillapla1 · X

RT @agingdoc1: Follistatin - why is this the new longevity trend?

Feb 14, 2024 · 5 shares · 356 followers View post →
Eleanor Sheekey
@EleanorSheekey · X

RT @agingdoc1: Follistatin - why is this the new longevity trend?

Feb 14, 2024 · 5 shares · 4,875 followers View post →
The Longevist
@Dr_coachbear · X

RT @agingdoc1: Follistatin - why is this the new longevity trend?

Feb 13, 2024 · 5 shares · 516,304 followers View post →
Chris Fetterly — e/acc
@ChrisFetterly · X

RT @agingdoc1: Follistatin - why is this the new longevity trend?

Feb 13, 2024 · 5 shares · 516 followers View post →
CRISPR GLENN
@CrisprGlenn · X

RT @agingdoc1: Follistatin - why is this the new longevity trend?

Feb 13, 2024 · 5 shares · 2,630 followers View post →
Agingdoc
@agingdoc1 · X

Follistatin - why is this the new longevity trend?

Feb 13, 2024 · 33 likes · 5 shares · 40,973 followers View post →
Longevity for everyone
@Happy_Long_Life · X

@bhuvanyu1 @bryan_johnson If you google it you will find a big scientific literature about it and different companies already offering it for rich body builders who want go gain muscles easily. Follistatin Gene Delivery Enhances Muscle Growth and Strength in Nonhuman Primates https://t.co/rrnoc7pnGn

Oct 3, 2023 · 125 followers View post →
Longevity for everyone
@Happy_Long_Life · X

@WilliamMegenney @bryan_johnson You can simply Google Follistatin gene therapy. Follistatin Gene Delivery Enhances Muscle Growth and Strength in Nonhuman Primates https://t.co/rrnoc7pnGn

Oct 2, 2023 · 3 likes · 125 followers View post →