Nutr Metab (Lond) April 2010 PMID 20412570

Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet: Case Report.

Giulio Zuccoli, Norina Marcello, Anna Pisanello, Franco Servadei, Salvatore Vaccaro, Purna Mukherjee, Thomas N Seyfried

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Mentions

39
Peak: 7 in Jan 2022
across 5 sources since Mar 2019

Extended reach

24,066
potential audience

Total likes

60

Video views

1,514

Mentions per month

Mar 2019 – Jun 2025

Where it's discussed

  • X / Twitter16 posts
  • Facebook9 posts
  • News6 articles
  • Blogs6 articles
  • YouTube2 videos

AI synopsis

What people are saying

The discussions reflect a cautious curiosity, mentioning specific outcomes such as 20% weight loss and no visible tumor tissue after two months, which suggests some recognition of promising results. At the same time, skepticism appears in comments about the small sample size and need for further research, exemplified by phrases like 'not great' and points about missing factors in diet plans. Overall, tone varies from hopeful to doubtful, influencing the moderate scores across all dimensions.

AgreementNeither agree nor disagree

The discussions show mixed opinions, with some skepticism about the results and others more open to considering the ketogenic approach as promising.

InterestModerate interest

Overall, there is a moderate level of curiosity, especially around the scientific implications and case outcomes, rather than deep engagement with every detail.

EngagementModerate engagement

Participants reference specific details like weight loss, tumor regression, and biomarker changes, indicating a moderate but meaningful engagement.

ImpactModerate impact

The discussion hints at potential clinical significance, but the reliance on a single case report limits the perceived direct impact on treatment protocols.

Abstract in brief

  • This case study explores the potential benefits of combining standard glioblastoma multiforme (GBM) treatment with a restricted ketogenic diet, which is traditionally used for epilepsy, to target tumor energy metabolism.
  • After implementing a water-only fast and a low-carb, high-fat ketogenic diet alongside standard therapy, the patient experienced significant tumor regression and weight loss, with no detectable tumor tissue on imaging after two months.
  • The report suggests that integrating a ketogenic diet with conventional treatments might enhance the response in GBM patients, potentially offering a new approach to managing this aggressive brain tumor, especially given the rarity of rapid remission in older patients with incomplete surgery.]

Top posts

Most liked on X and Bluesky
Dave Jackson
@naplesdave · X

@SteveHogMac https://t.co/aFUhOkstvO

Jan 19, 2022 · 7 likes · 3 shares · 4,442 followers View post →
KetoScience
@KetoScience · X

After 2 months treatment, the patient's body weight was reduced by about 20% and no discernable brain tumor tissue was detected, biomarker changes showed reduced levels of blood glucose and elevated levels of urinary ketones. #verylowcarb #keto #science https://t.co/A54Z13BuxF

Mar 28, 2019 · 4 likes · 668 followers View post →
KetoScience
@KetoScience · X

After two months treatment, the patient's body weight was reduced by about 20% and no discernable brain tumor tissue was detected. #cancer #keto #science https://t.co/0IyONnzerY

Apr 13, 2019 · 3 likes · 668 followers View post →
Quidama
@IamBreastCancer · X

"Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet: Case Report" - a single pt, 2 months tmt...20% body wt reduction & biomarker changes; tumor recurrence 10 weeks after suspension of strict diet therapy. Not great.

Aug 4, 2019 · 2 likes · 1,813 followers View post →
KetoScience
@KetoScience · X

After 2 months treatment, the patient's body weight was reduced by about 20% and no discernable brain tumor tissue was detected, biomarker changes showed reduced levels of blood glucose and elevated levels of urinary ketones. #verylowcarb #keto #science https://t.co/A54Z13BuxF

Jul 11, 2019 · 2 likes · 668 followers View post →
Dave Jackson
@naplesdave · X

@BaKetoBakery @WorkingCap205 https://t.co/aFUhOkstvO

Jan 19, 2022 · 1 like · 1 share · 4,442 followers View post →

All mentions

gozde dalkiran
@DalkiranGo35844 · X

qebûl kiriye ku bibe beşek ji vê lêkolînê. Di nav 3 mehan de, tumora wî êdî di MRI û PET scan de xuya bû. . https://t.co/OywayKFU9Y Ruta 6c û Calcerea Phos 3 DH @merck @OrganonLatam #Gardasil kûl

Jun 23, 2025 View post →
Brushfire Fairytale
@mothrfunkr · X

@BreezerGalway @RoxxoDr @SwaledaleMutton @LaymansScience @BerryTartlet You have demonstrated you don’t know how to read let alone understand science. https://t.co/giDXQ99tO9

Jan 13, 2025 · 1,641 followers View post →
Aquarius-elect
@Aquarius3_0 · X

@ichudov We should question everything, but never exclude anything! Look at the Ketogenic Diet and e.g. brain tumors. Or look at the research of Thomas Seyfried (@tnseyfried). I've seen/researched a lot of successful treated cases myself. So: NEVER SAY NEVER! https://t.co/oWJ8XZKBUF

Feb 3, 2024 · 1,372 followers View post →
Rob Etto
@Etto_R_Flo · X

@jarlebreivik @seagertp @gordon_fox76654 @travelingenes It’s a restricted, vegan, ketogenic diet - you are missing 2/3. Look up Longo and the efficacy he is seeing with the FMD - it’s not child’s play. Alone, the restriction helps but it’s not a cure. https://t.co/15UiH1iV5p

Jan 15, 2024 · 1 like · 283 followers View post →
Dave Jackson
@naplesdave · X

@Mark_D_Holland https://t.co/aFUhOkaS7e

Jan 20, 2022 · 4,442 followers View post →
Chapulinne
@chapulinne · X

RT @naplesdave: @SteveHogMac https://t.co/aFUhOkstvO

Jan 19, 2022 · 3 shares · 335 followers View post →
Chapulinne
@chapulinne · X

RT @naplesdave: @BaKetoBakery @WorkingCap205 https://t.co/aFUhOkstvO

Jan 19, 2022 · 1 share · 335 followers View post →
Dave Jackson
@naplesdave · X

@BaKetoBakery @WorkingCap205 https://t.co/aFUhOkstvO

Jan 19, 2022 · 1 like · 1 share · 4,442 followers View post →
Felito
@peraltaf · X

RT @naplesdave: @SteveHogMac https://t.co/aFUhOkstvO

Jan 19, 2022 · 3 shares · 707 followers View post →
Scott Anderson
@oxLA_alldisease · X

RT @naplesdave: @SteveHogMac https://t.co/aFUhOkstvO

Jan 19, 2022 · 3 shares · 216 followers View post →
Dave Jackson
@naplesdave · X

@SteveHogMac https://t.co/aFUhOkstvO

Jan 19, 2022 · 7 likes · 3 shares · 4,442 followers View post →
Dr. Websternator
@Chris_Lavina · X

@ronjdaugherty29 @GarrettIsVibin https://t.co/9cwW8CLWWE https://t.co/b5TLamjxas https://t.co/pvA1dZffH0 https://t.co/w5yuhCs4gj https://t.co/4kfDzwkqEl https://t.co/UZpLNMqLib

Aug 2, 2020 · 493 followers View post →
Quidama
@IamBreastCancer · X

"Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet: Case Report" - a single pt, 2 months tmt...20% body wt reduction & biomarker changes; tumor recurrence 10 weeks after suspension of strict diet therapy. Not great.

Aug 4, 2019 · 2 likes · 1,813 followers View post →
KetoScience
@KetoScience · X

After 2 months treatment, the patient's body weight was reduced by about 20% and no discernable brain tumor tissue was detected, biomarker changes showed reduced levels of blood glucose and elevated levels of urinary ketones. #verylowcarb #keto #science https://t.co/A54Z13BuxF

Jul 11, 2019 · 2 likes · 668 followers View post →
KetoScience
@KetoScience · X

After two months treatment, the patient's body weight was reduced by about 20% and no discernable brain tumor tissue was detected. #cancer #keto #science https://t.co/0IyONnzerY

Apr 13, 2019 · 3 likes · 668 followers View post →
KetoScience
@KetoScience · X

After 2 months treatment, the patient's body weight was reduced by about 20% and no discernable brain tumor tissue was detected, biomarker changes showed reduced levels of blood glucose and elevated levels of urinary ketones. #verylowcarb #keto #science https://t.co/A54Z13BuxF

Mar 28, 2019 · 4 likes · 668 followers View post →