Proc Natl Acad Sci U S A August 2010 PMID 20713720

Myonuclei acquired by overload exercise precede hypertrophy and are not lost on detraining.

J C Bruusgaard, I B Johansen, I M Egner, Z A Rana, K Gundersen

Mentions

66
Peak: 2 in Jul 2021
across 6 sources since Feb 2019

Extended reach

84,495
potential audience

Total likes

8

Video views

471

Mentions per month

Feb 2019 – Feb 2025

Where it's discussed

  • Facebook24 posts
  • News20 articles
  • X / Twitter13 posts
  • Reddit5 posts
  • YouTube2 videos
  • Blogs2 articles

AI synopsis

What people are saying

This collection of discussions demonstrates a strong consensus on the idea that myonuclei persist after muscle growth and facilitate quicker recovery, as seen in users referencing research, biological terms, and the significance of findings for training efficiency and aging, with tone emphasizing the importance and potential applications of the research.

AgreementModerate agreement

Most discussions agree that myonuclei are retained after muscle growth and contribute to muscle memory, reflecting support for the publication's conclusions.

InterestHigh interest

The discussions show high interest, with many users emphasizing the significance of muscle nuclei and implications for training and recovery.

EngagementModerate engagement

Users actively reference studies, concepts like 'muscle memory,' and physiological mechanisms, indicating thoughtful engagement.

ImpactModerate impact

The content appears impactful, influencing opinions on training practices, aging, and doping, with some discussions framing it as a key insight in muscle physiology.

Abstract in brief

  • Myonuclei added during strength training are established before muscle size increases and are retained even after periods of inactivity, helping maintain muscle memory.
  • These nuclei are protected from cell death during muscle atrophy caused by disuse or denervation, suggesting a lasting cellular component to muscle strength and size.
  • The capacity to generate new myonuclei declines with age, highlighting the importance of early strength training, and anabolic steroids may enhance myonuclei retention, impacting doping regulations.

Top posts

Most liked on X and Bluesky
♀️Ana -XX
@ana_iamhuman · X

En estudios recientes dicen hay un tipo de «memoria celular» pero dentro de las celulas musculares, explica el fenómeno de recuperar rápidamente la masa muscular perdida. Y esta «memoria» está relacionada al número de mionúcleos de las células musculares. https://t.co/Di78qPDO5z

Jul 22, 2021 · 2 likes · 1 share · 38,778 followers View post →
Nico
@nightgrey_ · X

@Eingrau @AnikiRip Just checked: It's called Nucleis (or myonucleis). They are built when you build muscle, but they stay for a long time (dormant), even if you lose the muscle. When you start exercising again; they spring into action and allow for faster muscle re-growth. https://t.co/KiWpAR1XWD

Jul 8, 2024 · 1 like · 425 followers View post →
Lauren Sellers
@lau_sellers · X

@CyberVirgem @StuProductions Nesse sentido, em um estudo de 2010 em camundongos foram encontrados mionúcleos de fibras musculares aumentados após exercício, com os mionúcleos adquiridos retidos durante a fase de destreinamento. https://t.co/AGOfTzerDL

Sep 19, 2023 · 1 like · 66 followers View post →
♀️Ana -XX
@ana_iamhuman · X

RT @ana_iamhuman: En estudios recientes dicen hay un tipo de «memoria celular» pero dentro de las celulas musculares, explica el fenómeno…

Jul 23, 2021 · 1 share · 38,778 followers View post →
Fitia App Español
@fitia_espanol · X

Feb 7, 2023 · 1,539 followers View post →
Kevin
@Tm_450SMK · X

@moto_km000 マッスルメモリーっていう状態ですね 元々の核は残ってるから新しく付けるより早く戻るらしいです https://t.co/qgWy2z9lNf

Mar 1, 2022 · 1,495 followers View post →

All mentions

BioVison
@davidleipi · X

Building muscle builds new muscle nuclei, which stay even after the muscle is atrophied because of detraining https://t.co/lpogTGnanf

Jul 21, 2024 · 13 followers View post →
Nico
@nightgrey_ · X

@Eingrau @AnikiRip Just checked: It's called Nucleis (or myonucleis). They are built when you build muscle, but they stay for a long time (dormant), even if you lose the muscle. When you start exercising again; they spring into action and allow for faster muscle re-growth. https://t.co/KiWpAR1XWD

Jul 8, 2024 · 1 like · 425 followers View post →
Lauren Sellers
@lau_sellers · X

@CyberVirgem @StuProductions Nesse sentido, em um estudo de 2010 em camundongos foram encontrados mionúcleos de fibras musculares aumentados após exercício, com os mionúcleos adquiridos retidos durante a fase de destreinamento. https://t.co/AGOfTzerDL

Sep 19, 2023 · 1 like · 66 followers View post →
Plaid
@Plaidololo · X

@CoachYali @Anna2Sexy_ https://t.co/XOb86kdonT

Feb 9, 2023 · 65 followers View post →
Fitia App Español
@fitia_espanol · X

Feb 7, 2023 · 1,539 followers View post →
Isabel M Guzmán
@Isabel_M_Guzman · X

@Good_C0ffin @ErinInTheMorn Myonuclei once had, muscle cells you will recover more easily than if you'd never had them: https://t.co/txPcJKQKnR Sorry.

Mar 27, 2022 · 97 followers View post →
Kevin
@Tm_450SMK · X

@moto_km000 マッスルメモリーっていう状態ですね 元々の核は残ってるから新しく付けるより早く戻るらしいです https://t.co/qgWy2z9lNf

Mar 1, 2022 · 1,495 followers View post →
Hyper High
@hyper_high · X

"Muscle Memory" Myonuclei acquired by overload exercise precede hypertrophy and are not lost on detraining https://t.co/lTMJXHQNac

Aug 15, 2021 · 498 followers View post →
♀️Ana -XX
@ana_iamhuman · X

RT @ana_iamhuman: En estudios recientes dicen hay un tipo de «memoria celular» pero dentro de las celulas musculares, explica el fenómeno…

Jul 23, 2021 · 1 share · 38,778 followers View post →
♀️Ana -XX
@ana_iamhuman · X

En estudios recientes dicen hay un tipo de «memoria celular» pero dentro de las celulas musculares, explica el fenómeno de recuperar rápidamente la masa muscular perdida. Y esta «memoria» está relacionada al número de mionúcleos de las células musculares. https://t.co/Di78qPDO5z

Jul 22, 2021 · 2 likes · 1 share · 38,778 followers View post →
Prof. Biology
@ResearchBiology · X

Myonuclei acquired by overload exercise precede hypertrophy and are not lost on detraining https://t.co/uK3dYWxinQ

May 6, 2021 · 635 followers View post →
自販機
@AWAXLAND_DandL · X

マッスルメモリーに関しては2010年に研究があって、(いちおう)実証はされてるっぽい なんかあったらこのツイートはすぐ削除します https://t.co/lB26AvWmEB

Apr 7, 2020 · 1,212 followers View post →
nacho
@Beastmaaster001 · X

Myonuclei acquired by overload exercise precede hypertrophy and are not lost on detraining https://t.co/vw600fcIQV

Feb 26, 2019 · 420 followers View post →