November 2011 PMID 20855349

Acute, subacute and long-term subjective effects of psilocybin in healthy humans: a pooled analysis of experimental studies.

Erich Studerus, Michael Kometer, Felix Hasler, Franz X Vollenweider

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Mentions

11
Peak: 2 in Aug 2020
across 2 sources since Jun 2018

Extended reach

931,810
potential audience

Total likes

16,647

Video views

899,223

Mentions per month

Jun 2018 – May 2025

Where it's discussed

  • X / Twitter7 posts
  • YouTube4 videos

AI synopsis

What people are saying

The discussions highlight key findings from the study, such as the manageable nature of acute adverse effects and the absence of long-term negative outcomes, with comments like 'All adverse reactions were successfully managed,' demonstrating a positive reception. The tone and choice of words, like 'hundreds of studies' and 'trusted research,' emphasize both scientific validity and potential impact, engaging readers who are interested in mental health and drug research.

AgreementModerate agreement

Most discussions acknowledge the study's findings, emphasizing that adverse effects are manageable and that research supports its safety in controlled environments.

InterestHigh interest

Posts show high enthusiasm and curiosity about long-term effects and implications, indicating active engagement with the topic.

EngagementModerate engagement

Participants reference specific details of the analysis, such as interpersonal support managing adverse reactions, reflecting a moderate depth of discussion.

ImpactModerate impact

The discourse underscores that the research influences perspectives on psilocybin's safety, suggesting it could shape future research and therapeutic approaches.

Abstract in brief

  • The pooled analysis of eight controlled studies involving 110 healthy participants found that psilocybin mainly caused profound but generally pleasurable and nonthreatening changes in mood, perception, and thought, with only the highest doses leading to some acute adverse reactions like dysphoria or anxiety.
  • Most adverse reactions were temporary and manageable through interpersonal support, with no need for medication, and no long-term negative effects such as perception disorders, ongoing psychosis, or substance abuse were observed during follow-up.
  • Overall, the study suggests that moderate doses of psilocybin, administered carefully in a monitored research environment, carry an acceptable level of risk for healthy, well-prepared individuals.]

Top posts

Most liked on X and Bluesky
Lagami Yight пражский крысяндрий
@lagami_yighht · X

@uhbif19 @Judas_na_kreste Первая же ссылка в гугле по запросу "psilocybin long term effects"

Dec 18, 2024 · 16 likes · 80 followers View post →
Dr. Rick Barnett, PsyD
@drrickbarnett · X

True words: “All acute adverse drug reactions were successfully managed by providing interpersonal support and did not need psychopharmacological intervention.” #psilocybin 2011 pooled analysis study https://t.co/IQYezOwHPh

Aug 9, 2020 · 1 like · 17,581 followers View post →
Anastasie
@Psychanastasie · X

Acute, subacute and long-term subjective effects of psilocybin inhealthy humans: A pooled analysis of experimental studies [Erich Studerus, Michael Kometer, et al. Journal of Psychopharmacology2011, Vol. 25, Issue 11, 1434–1452] https://t.co/xmQg0wRpde https://t.co/qMQ247juEu

Jun 26, 2021 · 1 like · 12,001 followers View post →
Matt Baggott
@mattbagg · X

@Neur0naut For rare adverse effects, I'd consider using the Studerus et al summary of Vollenweider lab's experience with psilocybin https://t.co/S3XKvtIMrw

Jan 22, 2020 · 1 like · 2,170 followers View post →
ligma sigma
@ligma__sigma · X

@PicoPaco17 @Johnny2Fingersz I literally did and all you were doing is trolling. You apparently cant even use a search engine or know how to define "healthy" or "tangible." There are hundreds of studies https://t.co/BTBuGxSVr4 https://t.co/mh2yQOVPgi https://t.co/etOOoCY0Zc https://t.co/qSx7NhLlJB

Sep 25, 2024 · 1 like · 636 followers View post →
Sansero Life Sciences
@Sansero_Life · X

Acute, subacute and long-term subjective effects of psilocybin in healthy humans: a pooled analysis of experimental studies: https://t.co/6oWdLOVUEQ #psilocybin #psilocybinresearch

Aug 28, 2020 · 95 followers View post →

All mentions

Lagami Yight пражский крысяндрий
@lagami_yighht · X

@uhbif19 @Judas_na_kreste Первая же ссылка в гугле по запросу "psilocybin long term effects"

Dec 18, 2024 · 16 likes · 80 followers View post →
ligma sigma
@ligma__sigma · X

@PicoPaco17 @Johnny2Fingersz I literally did and all you were doing is trolling. You apparently cant even use a search engine or know how to define "healthy" or "tangible." There are hundreds of studies https://t.co/BTBuGxSVr4 https://t.co/mh2yQOVPgi https://t.co/etOOoCY0Zc https://t.co/qSx7NhLlJB

Sep 25, 2024 · 1 like · 636 followers View post →
Dr. Mindful
@drmindfulonline · X

Studerus, E., Kometer, M., Hasler, F., & Vollenweider, F. X. (2011). Acute, subacute and long-term subjective effects of psilocybin in healthy humans: a pooled analysis of experimental studies. Journal of psychopharmacology (Oxford, England), 25(11), 1434–1452.

Mar 24, 2023 · 25 followers View post →
Anastasie
@Psychanastasie · X

Acute, subacute and long-term subjective effects of psilocybin inhealthy humans: A pooled analysis of experimental studies [Erich Studerus, Michael Kometer, et al. Journal of Psychopharmacology2011, Vol. 25, Issue 11, 1434–1452] https://t.co/xmQg0wRpde https://t.co/qMQ247juEu

Jun 26, 2021 · 1 like · 12,001 followers View post →
Sansero Life Sciences
@Sansero_Life · X

Acute, subacute and long-term subjective effects of psilocybin in healthy humans: a pooled analysis of experimental studies: https://t.co/6oWdLOVUEQ #psilocybin #psilocybinresearch

Aug 28, 2020 · 95 followers View post →
Dr. Rick Barnett, PsyD
@drrickbarnett · X

True words: “All acute adverse drug reactions were successfully managed by providing interpersonal support and did not need psychopharmacological intervention.” #psilocybin 2011 pooled analysis study https://t.co/IQYezOwHPh

Aug 9, 2020 · 1 like · 17,581 followers View post →
Matt Baggott
@mattbagg · X

@Neur0naut For rare adverse effects, I'd consider using the Studerus et al summary of Vollenweider lab's experience with psilocybin https://t.co/S3XKvtIMrw

Jan 22, 2020 · 1 like · 2,170 followers View post →