J Appl Physiol (1985) January 2011 PMID 21051570

Beneficial metabolic adaptations due to endurance exercise training in the fasted state.

Karen Van Proeyen, Karolina Szlufcik, Henri Nielens, Monique Ramaekers, Peter Hespel

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Mentions

49
Peak: 12 in Nov 2022
across 6 sources since Jan 2019

Extended reach

626,482
potential audience

Total likes

3,773

Video views

112,943

Mentions per month

Jan 2019 – Dec 2025

Where it's discussed

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AI synopsis

What people are saying

The overall discussions reflect strong agreement with the article’s findings, emphasizing how fasted exercise enhances oxidative capacity and lipid metabolism; words like "neat" and phrases such as "boosts oxidative capacity" demonstrate enthusiasm and perceived importance, contributing to a sense of high interest and impact.

AgreementStrong agreement

Most discussions support the findings, highlighting the metabolic benefits of fasted exercise and referencing evidence from the publication.

InterestHigh interest

Posts show high interest, with many expressing enthusiasm and referencing specific data points about oxidative capacity and lipid breakdown.

EngagementModerate engagement

Some comments provide detailed comments, including mention of research methods and implications, indicating a moderate level of deep engagement.

ImpactHigh impact

The discussions suggest that the publication influences opinions on exercise practices, especially regarding fasting, indicating high impact.

Abstract in brief

  • Training in a fasted state (without eating beforehand) boosts the muscle's ability to burn fat and increases enzymes related to oxidative energy production more than training with carbohydrates.
  • Fasted training also enhances breakdown of muscle fat stores (IMCL) during exercise and allows for higher fat oxidation rates, supporting better endurance performance.
  • Importantly, fasted training helps maintain blood glucose levels during exercise, which can be beneficial for energy stability, unlike fed training where blood glucose drops.]

Top posts

Most liked on X and Bluesky
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X

Fasted exercise is more effective than fed exercise to increase muscular oxidative capacity. Fasting enhances exercise-induced breakdown of lipids. In addition, fasting but not fed may prevent drop of blood glucose concentration during exercise. https://t.co/KuvuktYJdJ

Nov 25, 2022 · 214 likes · 22 shares · 298,176 followers View post →
Stephen Seiler
@StephenSeiler · X

Oldish but still a goody: This is quite lovely data describing the adaptive potency of 6wks of 4d/wk, 2h training sessions at 65% VO2 max among active but not endurance-trained subjects. Fasted or Carbed up https://t.co/BaMpvoasSL

May 6, 2021 · 44 likes · 5 shares · 33,261 followers View post →
Brady Holmer
@Brady_H · X

Neat article. Exercising while fasted boosts oxidative capacity > exercise with carbohydrates. #fasting #exercise #marathontraining Beneficial metabolic adaptations due to endurance exercise training in the fasted state | Journal of Applied Physiology https://t.co/OPOOHoCVhU

Jan 6, 2019 · 12 likes · 1 share · 27,339 followers View post →
KENTO/カジュアルに栄養の本質を学べる学校を作る。
@sudokeeen · X

参考 https://t.co/1EOQmRRo5f

Jul 2, 2024 · 7 likes · 52,134 followers View post →
Bartosz Czekała
@UniversOfMemory · X

@OblObserver @fmfclips Just an example, if you're interested: https://t.co/uo1IlOzpLK

Jun 5, 2025 · 6 likes · 5,561 followers View post →
Daniel Rowland
@dwrowland · X

Exercising in a fasted (F) state from 2010: "F is more effective than CHO to increase muscular oxidative capacity and at the same time enhances exercise induced net IMCL degradation" https://t.co/oK6F7QH9er

Oct 4, 2021 · 3 likes · 6,517 followers View post →

All mentions

Bartosz Czekała
@UniversOfMemory · X

@OblObserver @fmfclips Just an example, if you're interested: https://t.co/uo1IlOzpLK

Jun 5, 2025 · 6 likes · 5,561 followers View post →
Dr Murphy WeightLoss
@TakeWeightOffMD · X

RT @Mangan150: Fasted exercise is more effective than fed exercise to increase muscular oxidative capacity. Fasting enhances exercise-indu…

Sep 16, 2024 · 22 shares · 7,030 followers View post →
KENTO/カジュアルに栄養の本質を学べる学校を作る。
@sudokeeen · X

参考 https://t.co/1EOQmRRo5f

Jul 2, 2024 · 7 likes · 52,134 followers View post →
Greg Mushen
@gregmushen · X

@drpablocorral @AdrianSotoMota @JohnKastelein @SBakerMD Pablo, check out this paper: Beneficial metabolic adaptations due to endurance exercise training in the fasted state doi: 10.1152/japplphysiol.00907.2010 “consistent training with low initial glycogen level due to dietary carbohydrate restriction between training sessions

Feb 27, 2024 · 1 like · 30,588 followers View post →
kike
@FUENTESMANZULLI · X

RT @Mangan150: Fasted exercise is more effective than fed exercise to increase muscular oxidative capacity. Fasting enhances exercise-indu…

Jan 23, 2024 · 22 shares · 248 followers View post →
kike
@FUENTESMANZULLI · X

RT @Mangan150: Fasted exercise is more effective than fed exercise to increase muscular oxidative capacity. Fasting enhances exercise-indu…

Oct 14, 2023 · 22 shares · 248 followers View post →
kike
@FUENTESMANZULLI · X

RT @Mangan150: Fasted exercise is more effective than fed exercise to increase muscular oxidative capacity. Fasting enhances exercise-indu…

Jun 15, 2023 · 22 shares · 248 followers View post →
Think twice
@IBN7777 · X

RT @Mangan150: Fasted exercise is more effective than fed exercise to increase muscular oxidative capacity. Fasting enhances exercise-indu…

Apr 11, 2023 · 22 shares · 74 followers View post →
Penna
@Peninh4 · X

RT @Mangan150: Fasted exercise is more effective than fed exercise to increase muscular oxidative capacity. Fasting enhances exercise-indu…

Mar 1, 2023 · 22 shares · 1,502 followers View post →
krtyn ⁷
@yourloyalsinner · X

RT @Mangan150: Fasted exercise is more effective than fed exercise to increase muscular oxidative capacity. Fasting enhances exercise-indu…

Feb 26, 2023 · 22 shares · 197 followers View post →
alephh
@alephh · X

Beneficial metabolic adaptations to endurance exercise training in fasted state (FS) – Only FS prevented drop in blood glucose (P<0.05) – Maximal citrate synthase (+47%) and β-hydroxyacyl coenzyme A dehydrogenase (+34%) up in FS (P<0.05) but not in carbs https://t.co/4oYoX3y55G

Feb 22, 2023 · 389 followers View post →
kike
@FUENTESMANZULLI · X

RT @Mangan150: Fasted exercise is more effective than fed exercise to increase muscular oxidative capacity. Fasting enhances exercise-indu…

Jan 12, 2023 · 22 shares · 248 followers View post →
PietHeintheDane
@DanePiet · X

RT @Mangan150: Fasted exercise is more effective than fed exercise to increase muscular oxidative capacity. Fasting enhances exercise-indu…

Jan 12, 2023 · 22 shares · 45 followers View post →
Ted Clark
@tedrsa · X

RT @Mangan150: Fasted exercise is more effective than fed exercise to increase muscular oxidative capacity. Fasting enhances exercise-indu…

Nov 26, 2022 · 22 shares · 183 followers View post →
@LoreofRunning
@LoreofRunning1 · X

RT @Mangan150: Fasted exercise is more effective than fed exercise to increase muscular oxidative capacity. Fasting enhances exercise-indu…

Nov 26, 2022 · 22 shares · 7,894 followers View post →
Gutsy Gambit
@gutsy_gambit · X

RT @Mangan150: Fasted exercise is more effective than fed exercise to increase muscular oxidative capacity. Fasting enhances exercise-indu…

Nov 25, 2022 · 22 shares · 842 followers View post →
abogadodigital
@abogadodigital1 · X

RT @Mangan150: Fasted exercise is more effective than fed exercise to increase muscular oxidative capacity. Fasting enhances exercise-indu…

Nov 25, 2022 · 22 shares · 64 followers View post →
Melisse Moehlig
@MelisseMoehlig · X

RT @Mangan150: Fasted exercise is more effective than fed exercise to increase muscular oxidative capacity. Fasting enhances exercise-indu…

Nov 25, 2022 · 22 shares · 1,195 followers View post →
Bitcoin Érick ∞/21M
@bitcoinerick · X

RT @Mangan150: Fasted exercise is more effective than fed exercise to increase muscular oxidative capacity. Fasting enhances exercise-indu…

Nov 25, 2022 · 22 shares · 1,400 followers View post →
Patrick Willaert
@PatrickWillaer2 · X

RT @Mangan150: Fasted exercise is more effective than fed exercise to increase muscular oxidative capacity. Fasting enhances exercise-indu…

Nov 25, 2022 · 22 shares · 142 followers View post →
George Dorunda
@Dorunda · X

RT @Mangan150: Fasted exercise is more effective than fed exercise to increase muscular oxidative capacity. Fasting enhances exercise-indu…

Nov 25, 2022 · 22 shares · 2,153 followers View post →
kike
@FUENTESMANZULLI · X

RT @Mangan150: Fasted exercise is more effective than fed exercise to increase muscular oxidative capacity. Fasting enhances exercise-indu…

Nov 25, 2022 · 22 shares · 248 followers View post →
Ernesto Rodríguez
@elatletadeltao · X

El ejercicio en ayunas tiene muchos beneficios metabolicos.⬇️ https://t.co/JTXBrP0I0q

Nov 25, 2022 · 36 followers View post →
ConcernedCitizen.io
@Serious_Serb · X

RT @Mangan150: Fasted exercise is more effective than fed exercise to increase muscular oxidative capacity. Fasting enhances exercise-indu…

Nov 25, 2022 · 22 shares · 3,202 followers View post →
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X

Fasted exercise is more effective than fed exercise to increase muscular oxidative capacity. Fasting enhances exercise-induced breakdown of lipids. In addition, fasting but not fed may prevent drop of blood glucose concentration during exercise. https://t.co/KuvuktYJdJ

Nov 25, 2022 · 214 likes · 22 shares · 298,176 followers View post →
Daniel Rowland
@dwrowland · X

Exercising in a fasted (F) state from 2010: "F is more effective than CHO to increase muscular oxidative capacity and at the same time enhances exercise induced net IMCL degradation" https://t.co/oK6F7QH9er

Oct 4, 2021 · 3 likes · 6,517 followers View post →
Herb Case
@CaseHerb · X

RT @StephenSeiler: Oldish but still a goody: This is quite lovely data describing the adaptive potency of 6wks of 4d/wk, 2h training sessio…

May 6, 2021 · 5 shares · 196 followers View post →
Dimosthenis Gallis
@gallisdim · X

RT @StephenSeiler: Oldish but still a goody: This is quite lovely data describing the adaptive potency of 6wks of 4d/wk, 2h training sessio…

May 6, 2021 · 5 shares · 427 followers View post →
Pedro L. Valenzuela
@pl_valenzuela · X

Interesting! Sub-maximal exercise training (6 wk, 4 days/wk) on the fasted state benefits muscular oxidative capacity and intramyocellular lipid breakdown (but not VO2max or time trial performance) compared with fed state. IMO periodization is the key. https://t.co/0sX9xBYkRH https://t.co/HIhRK5tM0b

May 6, 2021 · 1 like · 2,779 followers View post →
Ken_Buckley
@y2kenb · X

RT @StephenSeiler: Oldish but still a goody: This is quite lovely data describing the adaptive potency of 6wks of 4d/wk, 2h training sessio…

May 6, 2021 · 5 shares · 590 followers View post →
Gordon Simpson
@ggsimpsonrun · X

RT @StephenSeiler: Oldish but still a goody: This is quite lovely data describing the adaptive potency of 6wks of 4d/wk, 2h training sessio…

May 6, 2021 · 5 shares · 203 followers View post →
Stephen Seiler
@StephenSeiler · X

Oldish but still a goody: This is quite lovely data describing the adaptive potency of 6wks of 4d/wk, 2h training sessions at 65% VO2 max among active but not endurance-trained subjects. Fasted or Carbed up https://t.co/BaMpvoasSL

May 6, 2021 · 44 likes · 5 shares · 33,261 followers View post →
Matthew Tamayo
@g33kbeast · X

@micsolana Sorry, I forgot that clubhouse doesn’t automute. Was going to talk about: https://t.co/memruwrrx9

Feb 9, 2021 · 404 followers View post →
Journal of Applied Physiology
@japplphysiol · X

RT @B_Holmer: Neat article. Exercising while fasted boosts oxidative capacity > exercise with carbohydrates. #fasting #exercise #marathontr…

Jan 6, 2019 · 1 share · 26,723 followers View post →
Brady Holmer
@Brady_H · X

Neat article. Exercising while fasted boosts oxidative capacity > exercise with carbohydrates. #fasting #exercise #marathontraining Beneficial metabolic adaptations due to endurance exercise training in the fasted state | Journal of Applied Physiology https://t.co/OPOOHoCVhU

Jan 6, 2019 · 12 likes · 1 share · 27,339 followers View post →
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