March 2011 PMID 21160058

Influence of acetaminophen and ibuprofen on skeletal muscle adaptations to resistance exercise in older adults.

Todd A Trappe, Chad C Carroll, Jared M Dickinson, Jennifer K LeMoine, Jacob M Haus, Bridget E Sullivan, Jonah D Lee, Bozena Jemiolo, Eileen M Weinheimer, Chris J Hollon

Download social card

Mentions

16
Peak: 3 in Jun 2024
across 5 sources since Feb 2020

Extended reach

249,609
potential audience

Total likes

4,354

Video views

52,316

Mentions per month

Feb 2020 – Jun 2025

Where it's discussed

  • X / Twitter9 posts
  • YouTube2 videos
  • Facebook2 posts
  • News2 articles
  • Bluesky1 posts

AI synopsis

What people are saying

Discussions reflect curiosity and careful consideration, with posts quoting specific aspects of the study such as its findings on older muscle and comparisons to prior research, often using phrases like 'interesting results' and 'counterintuitive.' The tone and references reveal a nuanced engagement with the material, balancing skepticism with insights.

AgreementNeither agree nor disagree

The discussions are mixed; some posts agree that the study suggests no significant effect, while others reference conflicting evidence, leading to a neutral agreement level.

InterestModerate interest

Many posts show curiosity, especially regarding differences between young and old muscle responses and the real-world implications of the research.

EngagementModerate engagement

Posts include questions, references to prior studies, and interpretations of the findings, indicating moderate engagement.

ImpactNeutral impact

Though some discuss how the findings align or contrast with previous work, the overall consensus suggests limited immediate impact on general practices or beliefs.

Top posts

Most liked on X and Bluesky
Stuart Phillips (he/him)
@mackinprof · X

@stevemagness @WillBrink @metapredict Enhances https://t.co/m7bSay8Zdx (splained away by age, fair enough) Does nothing https://t.co/5XZrEQeJLr https://t.co/K58GPiDjBE https://t.co/6PCBfgSpEl https://t.co/z0iwW49c9i

Jun 5, 2024 · 4 likes · 2 shares · 56,049 followers View post →
Stuart Phillips (he/him)
@mackinprof · X

@brianunverferth @robertallan87 @yogikh @NBTiller @JPhysiol Hm? Data to show ibuprofen blunts MPS? I think when you look at the totality of the evidence there’s no real evidence chronic ibuprofen does anything to muscle hypertrophy… maybe even enhances growth https://t.co/m7bSay8Zdx

Sep 9, 2022 · 3 likes · 56,049 followers View post →
Donald Xhuti
@xhutid · X

@DrDavidL @Roshan_Karia @Jozo_Grgic Yea but in young muscle. Old muscle presumably has higher inflammation so giving ibuprofen should dampen it and allow for greater increases in gains. So its weird that antioxidants wouldn’t work in older people here in the same way https://t.co/dZjFW91SOx

Aug 19, 2023 · 2 likes · 173 followers View post →
フィジカルノート NSCA-CPT, CSCS
@tt66845 · X

【鎮痛薬が筋タンパク質合成反応を鈍らせる】とする2011年の米国の論文→https://t.co/eTjbFth5Zm(アセトアミノフェンやイブプロフェンは日本でも痛み止めとして頻用されます。筋肉痛はトレーニングの繰り返しで自然と発生しにくくなるので、筋肥大のためには痛み止めを頻用しない方が良いでしょう) https://t.co/sUhNcrHdRq

Feb 19, 2020 · 1 like · 1 share · 1,225 followers View post →
Stuart Phillips (he/him)
@mackinprof · X

RT @mackinprof: @stevemagness @WillBrink @metapredict Enhances https://t.co/m7bSay8Zdx (splained away by age, fair enough) Does nothing htt…

Jun 5, 2024 · 2 shares · 56,049 followers View post →
Nick Krontiris
@nick_krontiris · X

Refs: https://t.co/q1tzMael2E https://t.co/SscwQvzQIQ https://t.co/3zDl5wFSeq

Feb 21, 2023 · 19,470 followers View post →

All mentions

João M
@nababu.toot.community.ap.brid.gy · Bluesky

Anti-inflamatório atrapalha a musculação? https://www.youtube.com/watch?v=-os4fi_5AJ0

Feb 3, 2025 View post →
Mind Your Science!
@MindYourSci · X

RT @mackinprof: @stevemagness @WillBrink @metapredict Enhances https://t.co/m7bSay8Zdx (splained away by age, fair enough) Does nothing htt…

Jun 6, 2024 · 2 shares · 130 followers View post →
Stuart Phillips (he/him)
@mackinprof · X

RT @mackinprof: @stevemagness @WillBrink @metapredict Enhances https://t.co/m7bSay8Zdx (splained away by age, fair enough) Does nothing htt…

Jun 5, 2024 · 2 shares · 56,049 followers View post →
Stuart Phillips (he/him)
@mackinprof · X

@stevemagness @WillBrink @metapredict Enhances https://t.co/m7bSay8Zdx (splained away by age, fair enough) Does nothing https://t.co/5XZrEQeJLr https://t.co/K58GPiDjBE https://t.co/6PCBfgSpEl https://t.co/z0iwW49c9i

Jun 5, 2024 · 4 likes · 2 shares · 56,049 followers View post →
Tommy Lundberg
@TLexercise · X

Note: A previous study by Trappe et al. showed the opposite results in elderly subjects. Perhaps the response differs between the young and the old! https://t.co/oIRnlUMT4y

Jan 2, 2024 · 7,798 followers View post →
Donald Xhuti
@xhutid · X

@DrDavidL @Roshan_Karia @Jozo_Grgic Yea but in young muscle. Old muscle presumably has higher inflammation so giving ibuprofen should dampen it and allow for greater increases in gains. So its weird that antioxidants wouldn’t work in older people here in the same way https://t.co/dZjFW91SOx

Aug 19, 2023 · 2 likes · 173 followers View post →
Nick Krontiris
@nick_krontiris · X

Refs: https://t.co/q1tzMael2E https://t.co/SscwQvzQIQ https://t.co/3zDl5wFSeq

Feb 21, 2023 · 19,470 followers View post →
Stuart Phillips (he/him)
@mackinprof · X

@brianunverferth @robertallan87 @yogikh @NBTiller @JPhysiol Hm? Data to show ibuprofen blunts MPS? I think when you look at the totality of the evidence there’s no real evidence chronic ibuprofen does anything to muscle hypertrophy… maybe even enhances growth https://t.co/m7bSay8Zdx

Sep 9, 2022 · 3 likes · 56,049 followers View post →
たいちゃん
@handball615kt · X

RT @tt66845: 【鎮痛薬が筋タンパク質合成反応を鈍らせる】とする2011年の米国の論文→https://t.co/eTjbFth5Zm(アセトアミノフェンやイブプロフェンは日本でも痛み止めとして頻用されます。筋肉痛はトレーニングの繰り返しで自然と発生しにくくなるので、…

Feb 19, 2020 · 1 share · 335 followers View post →
フィジカルノート NSCA-CPT, CSCS
@tt66845 · X

【鎮痛薬が筋タンパク質合成反応を鈍らせる】とする2011年の米国の論文→https://t.co/eTjbFth5Zm(アセトアミノフェンやイブプロフェンは日本でも痛み止めとして頻用されます。筋肉痛はトレーニングの繰り返しで自然と発生しにくくなるので、筋肥大のためには痛み止めを頻用しない方が良いでしょう) https://t.co/sUhNcrHdRq

Feb 19, 2020 · 1 like · 1 share · 1,225 followers View post →