Physiol Genomics May 2011 PMID 21325062

Chronic exposure to anabolic steroids induces the muscle expression of oxytocin and a more than fiftyfold increase in circulating oxytocin in cattle.

Nadia De Jager, Nicholas J Hudson, Antonio Reverter, Yong-Hong Wang, Shivashankar H Nagaraj, Linda M Cafe, Paul L Greenwood, Ross T Barnard, Kritaya P Kongsuwan, Brian P Dalrymple

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Peak: 13 in Feb 2021

across 3 sources since Feb 2021

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9,117

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2,043

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Feb 2021 – Dec 2024

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Reddit13 posts
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AI synopsis

What people are saying

Discussions revolve around the notable increase in oxytocin levels caused by anabolic steroids, with phrases like '50fold increase' and 'linked to muscle building' indicating interest in the biological implications. The tone is supportive and somewhat enthusiastic, reflecting curiosity about potential applications, but lacks deep scientific debate or critique. This suggests a moderate level of engagement and perceived impact based on how the results might influence understanding of muscle growth mechanisms.

AgreementModerate agreement

Most discussions acknowledge the findings, especially highlighting the significant increase in oxytocin linked to anabolic steroids, with some posts suggesting a positive connection to muscle growth.

InterestModerate interest

Posts show a moderate interest, focusing on the implications of oxytocin elevation and its potential role in muscle development, though not deeply exploring the scientific complexities.

EngagementNeutral engagement

The engagement is relatively superficial, with some posts expressing excitement or support but few detailed analyses or critical questions.

ImpactModerate impact

The conversations imply that the findings could influence future research or livestock practices, but the overall impact remains speculative for the general audience.

Abstract in brief

Chronic exposure to anabolic steroids like trenbolone acetate and estradiol in cattle leads to a significant increase in oxytocin expression in muscle tissue and circulating oxytocin levels, which may play a role in muscle growth.
Gene expression analysis shows that anabolic steroid treatment decreases fat metabolism-related genes while increasing those related to muscle growth, extracellular matrix, and cell cycle, indicating complex molecular changes in muscle tissue.
The study suggests that oxytocin, a neuropeptide hormone, might be a key mediator of the anabolic effects of steroids, especially during muscle development phases, supported by its high expression during early muscle growth and response to steroid treatment.]

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All mentions

Harnessing Oxytocin and IGF-1 for Enhanced Muscle Growth

Exploring how manipulation of growth factors like oxytocin and IGF-1 can stimulate hyperplasia in muscle tissue. The video discusses the emerging understanding of the oxytocin pathway's role in muscle development and…

Ultimate Formulations · Apr 28, 2024 1,269 views

Oxytocin's Role in Muscle Growth from Steroid Exposure Study

Chronic exposure to anabolic steroids like trenbolone acetate and estradiol increases oxytocin in muscle tissue and circulation, potentially mediating muscle growth through complex molecular changes.

Ultimate Formulations · Mar 11, 2024 572 views

The ER/IGF-1 Growth Pathway: Insights into Muscle Development and Steroid Effects

Chronic exposure to anabolic steroids like trenbolone acetate and estradiol in cattle leads to a significant increase in oxytocin expression in muscle tissue and circulating oxytocin levels, which may play a role in…

Ultimate Formulations · Dec 16, 2024 203 views

BioEnergetic Breaux

@ColliNof1 · X

Trenbolone raises tissue levels of oxytocin 50fold and may be linked to its muscle building effects Oxytocin=gainzzz https://t.co/4Hb9cEciuY

Nov 26, 2022 · 5 likes · 6,945 followers View post →

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https://journals.physiology.org/doi/full/10.1152/physiolgenomics.00226.2010https://pubmed.ncbi.nlm.nih.gov/24893201/ · https://pubmed.ncbi ...

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