J Neurosci April 2011 PMID 21471390

Brain mechanisms supporting the modulation of pain by mindfulness meditation.

Fadel Zeidan, Katherine T Martucci, Robert A Kraft, Nakia S Gordon, John G McHaffie, Robert C Coghill

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Mentions

123
Peak: 2 in Apr 2019
across 5 sources since Apr 2019

Extended reach

41,688
potential audience

Total likes

6

Video views

119

Mentions per month

Apr 2019 – Nov 2025

Where it's discussed

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AI synopsis

What people are saying

The discussions reflect a positive attitude toward the article, emphasizing its implications for pain relief with phrases like 'meditation can significantly reduce pain' and 'cut participants’ pain perception in half,' illustrating how the language underscores its practical significance. The tone is optimistic and focused on the potential benefits, demonstrating a strong interest and belief in the impact of mindfulness meditation as supported by neural evidence.

AgreementModerate agreement

Most discussions agree that mindfulness meditation can modulate pain through neural mechanisms, as reflected in phrases like 'brain mechanisms supporting the modulation of pain' and references to specific brain regions involved.

InterestHigh interest

The group shows high interest, with enthusiastic statements highlighting the effectiveness of mindfulness, such as 'Mindfulness can be an extremely effective remedy for pain,' indicating curiosity about its applications.

EngagementModerate engagement

Engagement is moderate; some discussions mention methods and neural pathways explicitly, but others are more general, suggesting an understanding and some depth in the interest.

ImpactModerate impact

Participants perceive the research as impactful, noting its potential for pain management, with comments like 'cut participants’ pain perception in half,' implying a meaningful influence on pain treatment practices.

Abstract in brief

  • Mindfulness meditation can significantly reduce both pain intensity and unpleasantness by influencing how the brain processes sensory information involved in pain.
  • Meditation decreases activity in the primary somatosensory cortex and engages regions like the anterior cingulate cortex, anterior insula, and orbitofrontal cortex, which are linked to cognitive regulation and re-evaluation of pain.
  • These findings suggest that meditation alters pain perception through multiple neural pathways, including reducing sensory signal processing and reframing emotional responses to pain.]

Top posts

Most liked on X and Bluesky
Burning Nights CRPS
@BNightsCRPS · X

Brain Mechanisms Supporting the Modulation of Pain by Mindfulness Meditation. #chronicpain #CRPS https://t.co/PrBlsYovtp

Sep 4, 2019 · 3 likes · 2 shares · 10,655 followers View post →
UltimApe
@ultimape · X

"Meditation-induced reductions in pain intensity ratings were associated with increased activity in the anterior cingulate cortex and anterior insula" https://t.co/ZI1ryVDMx0 but how exactly? https://t.co/LYDGFlWtDX

May 6, 2019 · 1 like · 6,757 followers View post →
Cristian Marin
@Cristian_Psic · X

@PsicoConductual Brain Mechanisms Supporting the Modulation of Pain by Mindfulness Meditation https://t.co/hxd62k49yb

Feb 7, 2020 · 1 like · 960 followers View post →
Chris✞chronicpainDAD
@ChronicPainDad · X

RT @BNightsCRPS: Brain Mechanisms Supporting the Modulation of Pain by Mindfulness Meditation. #chronicpain #CRPS https://t.co/PrBlsYovtp

Sep 4, 2019 · 2 shares · 22,561 followers View post →
☁︎ioana
@ioanaaa_v · X

“Brain Mechanisms Supporting the Modulation of Pain by Mindfulness Meditation” https://t.co/SzPfPOk6Qj https://t.co/TeGL0Lc1Jn

Nov 4, 2024 · 384 followers View post →
JP∆
@ndorobey_ix · X

2. Zeidan, F., et al. (2011). Brain mechanisms supporting the modulation of pain by mindfulness meditation. Journal of Neuroscience, 31(14), 5540–5548. · Bukti bahwa meditasi dapat menginduksi analgesik melalui mekanisme prefrontal dan PAG.

Nov 10, 2025 · 135 followers View post →

All mentions

JP∆
@ndorobey_ix · X

2. Zeidan, F., et al. (2011). Brain mechanisms supporting the modulation of pain by mindfulness meditation. Journal of Neuroscience, 31(14), 5540–5548. · Bukti bahwa meditasi dapat menginduksi analgesik melalui mekanisme prefrontal dan PAG.

Nov 10, 2025 · 135 followers View post →
☁︎ioana
@ioanaaa_v · X

“Brain Mechanisms Supporting the Modulation of Pain by Mindfulness Meditation” https://t.co/SzPfPOk6Qj https://t.co/TeGL0Lc1Jn

Nov 4, 2024 · 384 followers View post →
Cristian Marin
@Cristian_Psic · X

@PsicoConductual Brain Mechanisms Supporting the Modulation of Pain by Mindfulness Meditation https://t.co/hxd62k49yb

Feb 7, 2020 · 1 like · 960 followers View post →
Chris✞chronicpainDAD
@ChronicPainDad · X

RT @BNightsCRPS: Brain Mechanisms Supporting the Modulation of Pain by Mindfulness Meditation. #chronicpain #CRPS https://t.co/PrBlsYovtp

Sep 4, 2019 · 2 shares · 22,561 followers View post →
Burning Nights CRPS
@BNightsCRPS · X

Brain Mechanisms Supporting the Modulation of Pain by Mindfulness Meditation. #chronicpain #CRPS https://t.co/PrBlsYovtp

Sep 4, 2019 · 3 likes · 2 shares · 10,655 followers View post →
Global Yoga Therapy Day
@yoga_global · X

This study explored the impact of the practice of mindfulness meditation on brain areas associated with pain modulation. #GlobalYogaTherapyDay #YogaforBetterHealth #GYTDPainWeek #Meditation https://t.co/OcmvpM6HzP https://t.co/k5BAlUxvk0

Jun 27, 2019 · 102 followers View post →
UltimApe
@ultimape · X

"Meditation-induced reductions in pain intensity ratings were associated with increased activity in the anterior cingulate cortex and anterior insula" https://t.co/ZI1ryVDMx0 but how exactly? https://t.co/LYDGFlWtDX

May 6, 2019 · 1 like · 6,757 followers View post →
Tribe Treatment
@tribetreatment · X

Did you know? Mindfulness can be an extremely effective remedy for pain. In a recent study, just 4 days of mindfulness meditation cut participants’ pain perception in half compared to those who didn’t practice. https://t.co/RsossyArbe https://t.co/dyzChmrHq0

Apr 19, 2019 · 4 followers View post →
Tribe Treatment
@tribetreatment · X

Did you know? Mindfulness can be an extremely effective remedy for pain. In a recent study, just 4 days of mindfulness meditation cut participants’ pain perception in half compared to those who didn’t practice. https://t.co/RsossyArbe https://t.co/R4lffp3FZj

Apr 17, 2019 · 4 followers View post →