@drjohnm According to "Mr ApoB" himself; Allan Sniderman: "Over a 10-year period, a non-HDL-C strategy would prevent 300 000 more events than an LDL-C strategy, whereas an apoB strategy would prevent 500 000 more events than a non-HDL-C strategy." https://t.co/vbjsrtlcAp
A meta-analysis of low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol, and apolipoprotein B as markers of cardiovascular risk.
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Jun 2020 – Jul 2025Where it's discussed
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X / Twitter13 posts
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YouTube2 videos
AI synopsis
What people are saying
The group demonstrates strong support for the research findings, with posts highlighting the accuracy of apoB over traditional markers and emphasizing its potential to improve risk prediction. Words like 'most potent,' 'more lives saved,' and detailed numerical comparisons reflect high engagement and perception of substantial impact, while references to videos and reviews indicate active interest and deep discussion of the topic.
Most discussions strongly support the findings of the study, emphasizing the superior predictive value of apoB as a marker.
The discussions show high interest due to references to specific data, comparisons, and implications for cardiovascular risk prediction.
Participants engage by referencing detailed analysis, sharing videos, and debating the complexity of choosing appropriate markers.
Many posters believe the study has significant implications for clinical practice and population health, emphasizing potential to save lives.
Abstract in brief
- This meta-analysis compared the ability of three markers—apolipoprotein B (apoB), non-HDL cholesterol (nonHDLC), and LDL cholesterol (LDLC)—to predict cardiovascular events, using data from 12 studies with over 233,000 subjects, and found that apoB is the most effective marker.
- The study showed that apoB provides significantly better risk prediction than both nonHDLC and LDLC, with the potential to prevent more cardiovascular events over a decade if used as a target in treatment strategies.
- These findings support the importance of including apoB measurements in clinical practice for better cardiovascular risk assessment, as it adds substantial predictive value beyond traditional cholesterol measures.]
Top posts
Most liked on X and BlueskyNew YT video! https://t.co/6i8m6PLQEK https://t.co/MdRXk4qdxc
@foolproofvegan @PlantBasedLift1 @NzyenR https://t.co/y3yizxuBD3 start from this and check recently published reviews by him
@thalesnemo @ifixhearts https://t.co/NrXpqAh9US Whether analyzed individually or in head-to-head comparisons, apoB was the most potent marker of cardiovascular risk
@Lpa_Doc "Over 10 years, a non-HDL-C strategy could prevent 300K more events vs LDL-C, while an ApoB strategy may prevent 500K more than non-HDL-C" Discordance analysis shows ApoB is a more accurate marker for cardiovascular risk. All theoretical. https://t.co/rouaPh8A2m
@Gerave7 @EstebanDL La simplificación... suele pasar. No le quito la razón a Esteban sobre que "hay más complejidad" de lo que se habla, y es esa complejidad la que hace difícil elegir marcadores de predicción de riesgo. Es genial que haya debate: https://t.co/EOsTRDwd3D
All mentions
Apolipoprotein B as the Superior Marker for Cardiovascular Risk Assessment
This meta-analysis compared apoB, non-HDL cholesterol, and LDL cholesterol in predicting cardiovascular events, based on data from over 233,000 subjects, showing apoB is the most effective marker and enhances risk…
Impact of Lipid Lowering: Triglycerides vs LDL Cholesterol on Heart Disease Risk
This study explores whether lowering triglycerides or LDL cholesterol reduces coronary heart disease risk, showing both genetic variants associated with lipid level reductions lead to similar disease risk decrease…
RT @Hokkis: @drjohnm According to "Mr ApoB" himself; Allan Sniderman: "Over a 10-year period, a non-HDL-C strategy would prevent 300 000 mo…
@drjohnm According to "Mr ApoB" himself; Allan Sniderman: "Over a 10-year period, a non-HDL-C strategy would prevent 300 000 more events than an LDL-C strategy, whereas an apoB strategy would prevent 500 000 more events than a non-HDL-C strategy." https://t.co/vbjsrtlcAp
RT @mike_lustgarten: New YT video! https://t.co/6i8m6PLQEK https://t.co/MdRXk4qdxc
New YT video! https://t.co/6i8m6PLQEK https://t.co/MdRXk4qdxc
@Lpa_Doc "Over 10 years, a non-HDL-C strategy could prevent 300K more events vs LDL-C, while an ApoB strategy may prevent 500K more than non-HDL-C" Discordance analysis shows ApoB is a more accurate marker for cardiovascular risk. All theoretical. https://t.co/rouaPh8A2m
@Alicewants2know @MohammedAlo https://t.co/pXuPFGPV6S
@foolproofvegan @PlantBasedLift1 @NzyenR https://t.co/y3yizxuBD3 start from this and check recently published reviews by him
@gAlecsyBrain This study estimated that if high-risk treatment was decided using apoB rather than non-HDL-C and LDL-C (>70th percentile), more lives would be saved. They give cut-offs for apoB relative to LDL-C and non-HDL-C cut-offs at the end (just before Summary). https://t.co/bPJYwUU4X2
@TuckerGoodrich @ZahcM https://t.co/L48cHbYpk5
Wersja popularyzatorskiego tekstu z video prezentacją: https://t.co/k20t4h6IEL Potrzeba więcej krótkich i prostszych od tego materiałów 4/4
RT @SentientBlobBob: @thalesnemo @ifixhearts https://t.co/NrXpqAh9US Whether analyzed individually or in head-to-head comparisons, apoB was…
@thalesnemo @ifixhearts https://t.co/NrXpqAh9US Whether analyzed individually or in head-to-head comparisons, apoB was the most potent marker of cardiovascular risk
@Gerave7 @EstebanDL La simplificación... suele pasar. No le quito la razón a Esteban sobre que "hay más complejidad" de lo que se habla, y es esa complejidad la que hace difícil elegir marcadores de predicción de riesgo. Es genial que haya debate: https://t.co/EOsTRDwd3D
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