July 2011 PMID 21646368

Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline.

Michael F Holick, Neil C Binkley, Heike A Bischoff-Ferrari, Catherine M Gordon, David A Hanley, Robert P Heaney, M Hassan Murad, Connie M Weaver

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Mentions

28
Peak: 5 in Mar 2025
across 2 sources since Feb 2020

Extended reach

268,101
potential audience

Total likes

3,206

Video views

174,377

Mentions per month

Feb 2020 – Jul 2025

Where it's discussed

  • X / Twitter25 posts
  • YouTube3 videos

AI synopsis

What people are saying

The collective discussions demonstrate a high level of interest and moderate engagement, with posts referencing specific dosage ranges like 800–2000 IU/day and emphasizing the importance of avoiding megadosing, which shows thoughtful consideration of scientific details. The tone is generally informative and supportive, suggesting that the guideline updates are seen as a meaningful advancement in public health and clinical practice.

AgreementModerate agreement

Most discussions support the updated guidelines, emphasizing safer, more tailored dosing strategies.

InterestHigh interest

The topic of vitamin D supplementation and guideline changes appears highly relevant and engaging for the audience.

EngagementModerate engagement

Comments reference detailed dosage recommendations and debates around optimal intake, showing moderate depth.

ImpactModerate impact

Several posts highlight how the new guidelines could influence clinical practice and personal health decisions, indicating a moderate to high impact.

Abstract in brief

  • The guideline was developed by a Task Force of experts to help clinicians evaluate, treat, and prevent vitamin D deficiency, especially in those at risk, with recommendations based on systematic evidence review.
  • Due to the high prevalence of deficiency across all ages and limited food sources, the Task Force recommends vitamin D supplementation tailored to age and clinical circumstances, along with measuring serum 25-hydroxyvitamin D levels for diagnosis.
  • Currently, vitamin D testing is advised primarily for at-risk patients, and treatment with vitamin D2 or D3 is recommended for those diagnosed with deficiency; screening of low-risk individuals or using vitamin D for non-calcemic cardiovascular benefits is not supported by sufficient evidence.]

Top posts

Most liked on X and Bluesky
IntegralAnswers
@IntegralAnswers · X

8/ OPTIMAL LEVELS - DOSING: Don’t megadose. The sweet spot for 25(OH)D is: •30–50 ng/mL (75–125 nmol/L) •Routine doses: 800–2000 IU/day is generally safe Toxicity starts >10,000 IU/day long-term. Ref: Holick et al, J Clin Endocrinol Metab 2011 – https://t.co/b9xFmkvnIR

Mar 30, 2025 · 41 likes · 5 shares · 8,475 followers View post →
Dr Brad Stanfield
@BradStanfieldMD · X

Should You Still Be Taking Vitamin D? The Guidelines Just Changed. Vitamin D became a go-to supplement after the Endocrine Society’s 2011 guidelines pushed for doses up to 2,000 IU daily to keep levels above 30 ng/mL doi:10.1210/jc.2011-0385. But now, their 2024 update takes a https://t.co/i5xDcYP4uT

Jul 12, 2025 · 26 likes · 29,576 followers View post →
AntonioM
@saludatm · X

Oct 28, 2020 · 6 likes · 1 share · 382 followers View post →
Angie Asche
@eleatnutrition · X

https://t.co/BfzWU0n5Jf https://t.co/UrmPVibQrX https://t.co/F6zzD40anm https://t.co/obSiI4s6JT

Dec 28, 2020 · 5 likes · 2,011 followers View post →
こたつDr | 内科系最大の医師コミュニティ運営
@drkotatsu · X

ビタミンDの1日推奨摂取量(RDI)については、年齢や妊娠の有無などによって異なる多くのガイドラインが存在する(後ほど紹介)。 2011年に内分泌学会が発表したガイドラインは、主に観察研究に基づき、低ビタミンD状態の人のケアに重点を置いていた (https://t.co/COyKiTWYmJ)。

Oct 23, 2024 · 2 likes · 3,665 followers View post →
Il potere forte è sempre più nelle mani di pochi
@iniziamoda0 · X

https://t.co/7SHpJjeEMR guidelines, which recommended supplementation among all age groups.

Sep 10, 2024 · 1 like · 4,296 followers View post →

All mentions

Dr Brad Stanfield
@BradStanfieldMD · X

Should You Still Be Taking Vitamin D? The Guidelines Just Changed. Vitamin D became a go-to supplement after the Endocrine Society’s 2011 guidelines pushed for doses up to 2,000 IU daily to keep levels above 30 ng/mL doi:10.1210/jc.2011-0385. But now, their 2024 update takes a https://t.co/i5xDcYP4uT

Jul 12, 2025 · 26 likes · 29,576 followers View post →
Radka Lalonde
@RadkaLalonde · X

RT @IntegralAnswers: 8/ OPTIMAL LEVELS - DOSING: Don’t megadose. The sweet spot for 25(OH)D is: •30–50 ng/mL (75–125 nmol/L) •Routine doses…

Mar 30, 2025 · 5 shares · 3,259 followers View post →
Neely Ashmun
@NeelyAshmun · X

RT @IntegralAnswers: 8/ OPTIMAL LEVELS - DOSING: Don’t megadose. The sweet spot for 25(OH)D is: •30–50 ng/mL (75–125 nmol/L) •Routine doses…

Mar 30, 2025 · 5 shares · 2,592 followers View post →
Dave Corbin
@stratmandave · X

RT @IntegralAnswers: 8/ OPTIMAL LEVELS - DOSING: Don’t megadose. The sweet spot for 25(OH)D is: •30–50 ng/mL (75–125 nmol/L) •Routine doses…

Mar 30, 2025 · 5 shares · 5,410 followers View post →
Eve of Hearts @tigerpmimi@host.tld.
@tigerpmimi · X

RT @IntegralAnswers: 8/ OPTIMAL LEVELS - DOSING: Don’t megadose. The sweet spot for 25(OH)D is: •30–50 ng/mL (75–125 nmol/L) •Routine doses…

Mar 30, 2025 · 5 shares · 5,041 followers View post →
IntegralAnswers
@IntegralAnswers · X

8/ OPTIMAL LEVELS - DOSING: Don’t megadose. The sweet spot for 25(OH)D is: •30–50 ng/mL (75–125 nmol/L) •Routine doses: 800–2000 IU/day is generally safe Toxicity starts >10,000 IU/day long-term. Ref: Holick et al, J Clin Endocrinol Metab 2011 – https://t.co/b9xFmkvnIR

Mar 30, 2025 · 41 likes · 5 shares · 8,475 followers View post →
こたつDr | 内科系最大の医師コミュニティ運営
@drkotatsu · X

ビタミンDの1日推奨摂取量(RDI)については、年齢や妊娠の有無などによって異なる多くのガイドラインが存在する(後ほど紹介)。 2011年に内分泌学会が発表したガイドラインは、主に観察研究に基づき、低ビタミンD状態の人のケアに重点を置いていた (https://t.co/COyKiTWYmJ)。

Oct 23, 2024 · 2 likes · 3,665 followers View post →
Il potere forte è sempre più nelle mani di pochi
@iniziamoda0 · X

https://t.co/7SHpJjeEMR guidelines, which recommended supplementation among all age groups.

Sep 10, 2024 · 1 like · 4,296 followers View post →
Fit_Phil_B
@Fit_Phil_B · X

@blindclassic_ In der Publikation zb. (https://t.co/WLIhRay9EO). Die 600-800 sind wahrscheinlich nur das Minimum um einen Mangel auszugleichen. Die D3-Tabletten die man zb. beim Arzt bekommt, haben meist auch nur 1k IE drin, was für jmd ohne Mangel fast nichts ist.

Apr 26, 2022 · 1 like · 526 followers View post →
麻鳥 gone☘️
@radnaore · X

「ビタミンD欠乏症はすべての年齢層で非常に一般的であり、ビタミンDを含む食品はほとんどないことを考慮し、タスクフォースは、年齢および臨床状況に応じて、推奨される毎日の摂取量および許容上限レベルでの補給を推奨」 Journal of Clinical Endocrinology and Metabolism https://t.co/2NMV2LArIn

Apr 22, 2022 · 1 like · 1,925 followers View post →
Yo.Vivo.D
@YoVivoD · X

Referencia: 1. Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2011;96:1911–30.

Jan 6, 2022 · 1,111 followers View post →
Yo.Vivo.D
@YoVivoD · X

Referencia: 1. Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2011;96:1911–30.

Jan 6, 2022 · 1,111 followers View post →
Yo.Vivo.D
@YoVivoD · X

Referencia: 1. Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2011;96:1911–30.

Jan 6, 2022 · 1,111 followers View post →
Dr. Alfonso
@alfonsoabel · X

Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline | The Journal of Clinical Endocrinology & Metabolism | Oxford Academic https://t.co/cIO1sr0VpA

Nov 2, 2021 · 102 followers View post →
Yo.Vivo.D
@YoVivoD · X

Referencias: 1. Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2011;96:1911–30.

Aug 27, 2021 · 1,111 followers View post →
Yo.Vivo.D
@YoVivoD · X

Referencia: Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2011;96:1911–30

Aug 13, 2021 · 1 like · 1,111 followers View post →
Yo.Vivo.D
@YoVivoD · X

Referencias: Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2011;96:1911–30.

Aug 6, 2021 · 1 like · 1,111 followers View post →
Yo.Vivo.D
@YoVivoD · X

3. Holick MF, et al. Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2011 Jul;96(7):1911-30.

Jul 16, 2021 · 1,111 followers View post →
Yo.Vivo.D
@YoVivoD · X

3. Holick MF, et al. Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2011 Jul;96(7):1911-30.

Jul 16, 2021 · 1,111 followers View post →
Yo.Vivo.D
@YoVivoD · X

3. Holick MF, et al. Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2011 Jul;96(7):1911-30.

Jul 13, 2021 · 1,111 followers View post →
Angie Asche
@eleatnutrition · X

https://t.co/BfzWU0n5Jf https://t.co/UrmPVibQrX https://t.co/F6zzD40anm https://t.co/obSiI4s6JT

Dec 28, 2020 · 5 likes · 2,011 followers View post →
IberianCitizen
@IberianCitizen · X

RT @saludatm:

Oct 28, 2020 · 1 share · 12,901 followers View post →
AntonioM
@saludatm · X

Oct 28, 2020 · 6 likes · 1 share · 382 followers View post →
LdGülbaran
@mioagnusdei · X

@SleymanKanbola4 @dmet_47 @esraciftci75 @DrGunerSonmez ✔Evaluation Treatment and Prevention of Vitamin D Deficiency an Endocrine Society Clinical Practice Guideline  https://t.co/3wNOENsbzU

Sep 30, 2020 · 3,311 followers View post →
DR LI Health
@latirina · X

Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. - PubMed - NCBI https://t.co/p38g7MFplu

Feb 11, 2020 · 200 followers View post →