PubHawk
PLoS One December 2011 PMID 21750728

Highly asynchronous and asymmetric cleavage divisions accompany early transcriptional activity in pre-blastula medaka embryos.

Michael Kraeussling, Toni Ulrich Wagner, Manfred Schartl

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Mentions

9
Peak: 4 in Oct 2024
across 2 sources since Mar 2023

Extended reach

77,871
potential audience

Total likes

143

Video views

2,675

Mentions per month

Mar 2023 – May 2025

Where it's discussed

  • X / Twitter7 posts
  • YouTube2 videos

AI synopsis

What people are saying

Discussions reflect a mix of curiosity and casual interest, exemplified by comments about videos going viral and questions about cell sizes, which show interest in the biology. The tone varies from enthusiastic to skeptical, with some users referencing complex concepts like tumor types and embryonic stages, indicating moderate engagement but not a strong consensus on the article's broader impact.

AgreementModerate agreement

Most discussions acknowledge the significance of the research, but there's some skepticism about its novelty, such as the comment questioning early transcription preceding the MBT, which shows cautious agreement rather than full endorsement.

InterestHigh interest

The social discussions show high interest in the topic, with references to viral videos and curiosity about cell stages, indicating curiosity and engagement with early embryonic development.

EngagementModerate engagement

Some comments delve into technical details like cell sizes and tumor differentiation, demonstrating thoughtful engagement, but most are surface-level reactions or casual mentions.

ImpactNeutral impact

The influence of the publication seems moderate; some discussions recognize its importance for understanding developmental processes, but others focus on unrelated topics like viral videos and tumors, diluting perceived impact.

Abstract in brief

  • In early medaka embryos, cell divisions are asynchronous and diverse in size even before the traditional midblastula transition (MBT), with significant activation of zygotic gene transcription occurring shortly after the 64-cell stage.
  • Unlike typical models where the MBT marks the start of transcription and cell cycle desynchronization, medaka embryos show these events happening earlier, indicating that the shift from maternal to zygotic control is not strictly linked to the MBT.
  • These findings suggest that in medaka, the regulation of early development involves mechanisms beyond the previously assumed nucleus-to-cytoplasm ratio, highlighting species-specific differences in embryonic gene activation and cell cycle control.
Read the full abstract

Top posts

Most liked on X and Bluesky
bioZone
@thebiozone · X

was pleasantly surprised to find out a video we posted on tik tok went viral!! (185,000 views is considered viral for us

May 17, 2025 · 6 likes · 2 shares · 186 followers View post →
bioZone
@thebiozone · X

Teratomas are tumors derived from stem cells and can contain all sorts of cell types and structures, including hair, nervous tissue, and teeth. watch on YouTube to support us

Oct 6, 2024 · 4 likes · 1 share · 186 followers View post →
Michael Eisen
@mbeisen · X

@NeedhiBhalla There's stuff on 4-cell stage here - should be 1/2 that, no? https://t.co/6DadArwalc - so maybe 2x10^6 cubic microns if I'm reading table right.

Mar 22, 2023 · 1 like · 1 share · 73,113 followers View post →
April
@sciApril · X

RT @thebiozone: was pleasantly surprised to find out a video we posted on tik tok went viral!! (185,000 views is considered viral for us

May 17, 2025 · 2 shares · 620 followers View post →
April
@sciApril · X

RT @thebiozone: Teratomas are tumors derived from stem cells and can contain all sorts of cell types and structures, including hair, nervou…

Oct 6, 2024 · 1 share · 620 followers View post →
Malaika
@Maliqa_M · X

RT @thebiozone: was pleasantly surprised to find out a video we posted on tik tok went viral!! (185,000 views is considered viral for us

May 17, 2025 · 2 shares · 266 followers View post →

All mentions

April
@sciApril · X

RT @thebiozone: was pleasantly surprised to find out a video we posted on tik tok went viral!! (185,000 views is considered viral for us

May 17, 2025 · 2 shares · 620 followers View post →
Malaika
@Maliqa_M · X

RT @thebiozone: was pleasantly surprised to find out a video we posted on tik tok went viral!! (185,000 views is considered viral for us

May 17, 2025 · 2 shares · 266 followers View post →
bioZone
@thebiozone · X

was pleasantly surprised to find out a video we posted on tik tok went viral!! (185,000 views is considered viral for us

May 17, 2025 · 6 likes · 2 shares · 186 followers View post →
April
@sciApril · X

RT @thebiozone: Teratomas are tumors derived from stem cells and can contain all sorts of cell types and structures, including hair, nervou…

Oct 6, 2024 · 1 share · 620 followers View post →
bioZone
@thebiozone · X

media sources: Kraeussling et al https://t.co/EFRrdeOFWl https://t.co/zxQzcmlEa6 Ed Uthman https://t.co/9gV04GfMEH Ed Uthman https://t.co/IiaQEN8SUT Kessler et al https://t.co/rr5W0HnRXk https://t.co/DKvKkoGEM9

Oct 6, 2024 · 188 followers View post →
bioZone
@thebiozone · X

Teratomas are tumors derived from stem cells and can contain all sorts of cell types and structures, including hair, nervous tissue, and teeth. watch on YouTube to support us

Oct 6, 2024 · 4 likes · 1 share · 186 followers View post →
Michael Eisen
@mbeisen · X

@NeedhiBhalla There's stuff on 4-cell stage here - should be 1/2 that, no? https://t.co/6DadArwalc - so maybe 2x10^6 cubic microns if I'm reading table right.

Mar 22, 2023 · 1 like · 1 share · 73,113 followers View post →