December 2011 PMID 21818338

Spermidine promotes human hair growth and is a novel modulator of human epithelial stem cell functions.

Yuval Ramot, Stephan Tiede, Tamás Bíró, Mohd Hilmi Abu Bakar, Koji Sugawara, Michael P Philpott, Wesley Harrison, Marko Pietilä, Ralf Paus

Download social card

Mentions

15
Peak: 1 in Sep 2022
across 4 sources since Sep 2022

Extended reach

4,914
potential audience

Total likes

25

Video views

786

Mentions per month

Sep 2022 – Feb 2025

Where it's discussed

  • X / Twitter5 posts
  • News4 articles
  • YouTube3 videos
  • Facebook3 posts

AI synopsis

What people are saying

The overall tone reflects a mixture of curiosity and skepticism, with some users pointing out specific elements like hair follicles or stem cell markers, while others question the reliability of the findings, using words like 'not trustworthy' and simple questions like 'What am I reading right now?'. The tone and brevity indicate moderate engagement and interest but limited perception of immediate impact.

AgreementNeither agree nor disagree

The only explicit disagreement comes from Shirley Glass, who questions the trustworthiness of the study, indicating mixed opinions rather than broad disagreement.

InterestModerate interest

Several discussions show curiosity, such as questions about the content or reactions to the findings, suggesting moderate interest.

EngagementModerate engagement

Posts involve brief reactions and mentions of specific elements like human hair follicles and stem cell functions, demonstrating some engagement but not deep analysis.

ImpactNeutral impact

The discussions do not clearly suggest that the publication is seen as highly transformative, with some skepticism and basic curiosity observed.

Abstract in brief

  • Polyamines, particularly spermidine, play a crucial role in hair follicle growth and regulation, promoting hair shaft elongation and extending the growth phase of hair (anagen).
  • Spermidine enhances the expression of epithelial stem cell markers (K15 and K19) and influences stem cell behavior, as demonstrated by its effects on cell proliferation and gene expression in laboratory studies.
  • Excess spermidine may negatively feedback on polyamine synthesis, indicating a complex regulatory mechanism at play in hair follicle biology and stem cell function.

Top posts

Most liked on X and Bluesky
ptitloolou (she/her)
@ptitloolou · X

@ProfGraceHoward @mdjsoft @AnitaBeerToday @BadMedicalTakes Found the study, it's not trustworthy. https://t.co/fPoecfl76I

Aug 7, 2024 · 7 likes · 494 followers View post →
老化を遅らせることに成功しているかも
@roukaokurasu · X

Feb 10, 2024 · 4 likes · 2,514 followers View post →
Benny Shaps Doctor Wife
@RhiannonAlexis · X

What am I reading right now? Ramot, Y., et al. (2011). Spermidine promotes human hair growth and is a novel modulator of human epithelial stem cell functions. https://t.co/pddegppTsF

Sep 12, 2022 · 1 like · 902 followers View post →
Druryu
@cmrdu · X

@BradStanfieldMD Human scalp hair follicles. https://t.co/ehXPbje9uV

Nov 30, 2022 · 115 followers View post →

All mentions

Ehsan
@redandnewflesh · X

@shirleyglass_ https://t.co/e8xWiub83C

Feb 3, 2025 · 104 followers View post →
ptitloolou (she/her)
@ptitloolou · X

@ProfGraceHoward @mdjsoft @AnitaBeerToday @BadMedicalTakes Found the study, it's not trustworthy. https://t.co/fPoecfl76I

Aug 7, 2024 · 7 likes · 494 followers View post →
老化を遅らせることに成功しているかも
@roukaokurasu · X

Feb 10, 2024 · 4 likes · 2,514 followers View post →
Druryu
@cmrdu · X

@BradStanfieldMD Human scalp hair follicles. https://t.co/ehXPbje9uV

Nov 30, 2022 · 115 followers View post →
Benny Shaps Doctor Wife
@RhiannonAlexis · X

What am I reading right now? Ramot, Y., et al. (2011). Spermidine promotes human hair growth and is a novel modulator of human epithelial stem cell functions. https://t.co/pddegppTsF

Sep 12, 2022 · 1 like · 902 followers View post →