The discussions reveal a general consensus that the study is important, with posts highlighting the potential health risks posed by phthalates and emphasizing the need for further research. Words like 'significant,' 'impactful,' and references to pathways and public health issues illustrate both engagement and recognition of the study's importance.
AgreementModerate agreement
Most discussions acknowledge the significance of the research, with many accepting the findings on phthalates' role in cancer progression.
InterestHigh interest
Many posts demonstrate high curiosity and concern about the environmental and health implications of the study.
EngagementModerate engagement
Participants actively reference related pathways, such as HDAC6 and c-Myc, and discuss broader impacts on public health policies.
ImpactModerate impact
The discussions reflect a belief that this research could influence future studies and health guidelines, indicating a moderate but meaningful impact.
Abstract in brief
The study found that phthalates like BBP and DBP promote growth, movement, invasion, and tumor formation in estrogen receptor-negative breast cancer cells by activating the AhR receptor and a specific signaling pathway involving cAMP, PKA, and CREB1.
This pathway leads to increased levels of HDAC6, which helps assemble a transcription complex that boosts the expression of the cMyc oncogene, contributing to cancer progression.
Overall, the research uncovers a new way that phthalates can promote breast cancer growth outside of their traditional estrogenic effects, highlighting a potential environmental risk factor for hormone-independent breast cancers.
@medical_xpress @AACR #cancer #breastcancer #publichealth #metabolomics #methylomics #health #sustainability #NCDs #SDGs #exposome
Phthalates induce proliferation and invasiveness
of estrogen receptor‐negative breast cancer
through the AhR/HDAC6/c‐Myc signaling pathway
.
https://t.co/ngzcANX6kE
Aug 6, 2020 · 2 likes · 1 share · 4,585 followersView post →
FE
For health-promoting environments
@SilkeLeFay · X
@medical_xpress @NorthwesternU @ScienceAdvances #MYC
Butyl benzyl phthalate
promotes prostate cancer cell proliferation
through the miR-34a/c-myc axis.
https://t.co/oKDo79Vrp6
Phthalates
induce proliferation of
estrogen receptor‐negative breast cancer
through the AhR/HDAC6/c‐Myc signaling pathway
https://t.co/RP3uT3YL1q
#cancer #breastcancer #NCDs #publichealth #epidemiology #metabolomics #health #sustainability #methylomics
Phthalates induce proliferation and invasiveness
of estrogen receptor‐negative breast cancer
through the AhR/HDAC6/c‐Myc signaling pathway
.
https://t.co/eRO563wOOA
#breastcancer #womenshealth #ecotoxicology #HDAC #immunology #exposome #publichealth #endocrinology #oncology
Phthalates
induce proliferation and invasiveness of
estrogen receptor‐negative breast cancer
through the AhR/HDAC6/c‐Myc signaling pathway
.
https://t.co/RP3uT3YL1q
@medical_xpress @PNASNews .
Phthalates
induce proliferation of
estrogen receptor‐negative
breast cancer
through the AhR/HDAC6/c‐Myc signaling pathway
.
https://t.co/RP3uT3YL1q
#breastcancer #publichealth #womenshealth #healthpromotion #epidemiology #NCDs #sustainability #GreenNewDeal
Phthalates
induce proliferation and invasiveness of
estrogen receptor‐negative breast cancer
through the AhR/HDAC6/c‐Myc signaling pathway
.
https://t.co/eRO563wOOA
Water intake increases mesenteric lymph flow and the transport of albumin, fatty acids, and immune factors in rats, revealing a new perspective on intestinal absorption and innate immunity enhancement.
This video explores the potential health risks of bottled water, including its impact on the intestine, and discusses microplastics' toxicological effects on humans, sources, interactions, and future research directions.
Microplastics and nanoplastics are tiny plastic particles from degraded waste that threaten all living organisms. This video explores their sources, interactions, toxicity mechanisms, detection methods, and the…
This video explores the toxicological impact of microplastics and nanoplastics, sources, interactions, toxicity mechanisms, detection methods, and future research directions to understand their effects on health and the…
Microplastics and nanoplastics are tiny particles resulting from plastic degradation that accumulate in the environment and pose health risks. This video explores their sources, interactions with biological systems…
Studies on nanoplastics in bottled water reveal potential toxic effects and environmental impact, highlighting the importance of understanding their sources, interactions, and health risks as outlined in current…
This video explores how bottled water, especially plastic bottles, affects fertility and introduces the risks associated with microplastics and nanoplastics, including their sources, toxic effects, and potential impact…
Bottled water can harm our brain and gut, as studies show. Microplastics from plastic waste, especially during increased plastic use in the COVID-19 pandemic, pose health risks due to their small size and interaction…
Discover the truth behind plastic packaging and its impact on our health and environment. This video explores how microplastics and nanoplastics, resulting from plastic degradation, pose risks to health and ecosystems…
#breastcancer #womenshealth #ecotoxicology #HDAC #immunology #exposome #publichealth #endocrinology #oncology
Phthalates
induce proliferation and invasiveness of
estrogen receptor‐negative breast cancer
through the AhR/HDAC6/c‐Myc signaling pathway
.
https://t.co/RP3uT3YL1q
@medical_xpress @PNASNews .
Phthalates
induce proliferation of
estrogen receptor‐negative
breast cancer
through the AhR/HDAC6/c‐Myc signaling pathway
.
https://t.co/RP3uT3YL1q
#womenshealth #oncology
Phthalates induce
proliferation and invasiveness
of estrogen receptor‐negative
breast cancer
through the AhR/HDAC6/c‐Myc signaling pathway
.
https://t.co/ngzcANG3iE
@medical_xpress @NorthwesternU @ScienceAdvances #MYC
Butyl benzyl phthalate
promotes prostate cancer cell proliferation
through the miR-34a/c-myc axis.
https://t.co/oKDo79Vrp6
Phthalates
induce proliferation of
estrogen receptor‐negative breast cancer
through the AhR/HDAC6/c‐Myc signaling pathway
https://t.co/RP3uT3YL1q
#breastcancer #publichealth #womenshealth #healthpromotion #epidemiology #NCDs #sustainability #GreenNewDeal
Phthalates
induce proliferation and invasiveness of
estrogen receptor‐negative breast cancer
through the AhR/HDAC6/c‐Myc signaling pathway
.
https://t.co/eRO563wOOA
#breastcancer #agedcare #NCDs #publichealth
Hair concentrations of phthalate metabolites
need to be monitored.
Phthalates induce proliferation and invasiveness of
estrogen receptor‐negative breast cancer
through the AhR/HDAC6/c‐Myc signaling pathway
.
https://t.co/eRO563wOOA
#cancer #breastcancer #NCDs #publichealth #epidemiology #metabolomics #health #sustainability #methylomics
Phthalates induce proliferation and invasiveness
of estrogen receptor‐negative breast cancer
through the AhR/HDAC6/c‐Myc signaling pathway
.
https://t.co/eRO563wOOA
@medical_xpress @AACR #cancer #breastcancer #publichealth #metabolomics #methylomics #health #sustainability #NCDs #SDGs #exposome
Phthalates induce proliferation and invasiveness
of estrogen receptor‐negative breast cancer
through the AhR/HDAC6/c‐Myc signaling pathway
.
https://t.co/ngzcANX6kE
Aug 6, 2020 · 2 likes · 1 share · 4,585 followersView post →
N
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