Bioessays January 2012 PMID 22057551

The evolution of menstruation: a new model for genetic assimilation: explaining molecular origins of maternal responses to fetal invasiveness.

Deena Emera, Roberto Romero, Günter Wagner

Mentions

28
Peak: 3 in May 2025
across 7 sources since Apr 2016

Extended reach

1,365,893
potential audience

Total likes

50,664

Video views

1,327,848

Mentions per month

Apr 2016 – Aug 2025

Where it's discussed

  • X / Twitter9 posts
  • News5 articles
  • Facebook4 posts
  • Bluesky3 posts
  • YouTube3 videos
  • Reddit2 posts
  • Blogs2 articles

AI synopsis

What people are saying

The posts reflect a high level of interest in the evolutionary origins of menstruation, with examples like the mention of diverse species that menstruate and the discussion of its adaptive functions. The tone varies from curiosity to scientific analysis, showing both engagement and recognition of the article’s significance in understanding reproductive biology.

AgreementModerate agreement

Most discussions recognize the validity and importance of the research, with some supporting the idea that menstruation evolved as a defense mechanism.

InterestHigh interest

The discussions consistently show curiosity about the evolutionary aspects of menstruation across different species, indicating high interest.

EngagementModerate engagement

Participants reference multiple sources, models, and processes, suggesting active engagement with the scientific concepts.

ImpactModerate impact

While the discussions highlight interest and engagement, they mostly focus on understanding rather than immediate practical implications, leading to a moderate impact score.

Abstract in brief

  • The paper explains that human menstruation likely evolved from a process called spontaneous decidualization (SD), which is a hormone-driven change in the uterine lining, as a result of maternal-fetal conflicts over pregnancy.
  • It proposes that SD originally evolved in nonmenstruating species as a fetal-induced reaction, but in humans, it became genetically fixed, allowing the body to prepare for pregnancy independently of fetal signals.
  • The authors present three models of how SD might have evolved through genetic assimilation, and suggest that understanding this process can help us better understand reproductive health issues like endometriosis and pregnancy loss.]

Top posts

Most liked on X and Bluesky
Dhiordan Lovestain
@DhiordanLove · X

E se você ficou curioso para entender mais sobre como a menstruação funciona e como ela ocorre nas espécies de mamíferos placentários, vem conferir tudo em nosso vídeo: https://t.co/7PsDPED5YW https://t.co/r8iGttIz4u

May 17, 2025 · 32 likes · 33,160 followers View post →
the original Aloof Wife
@cpi.pinball.horse · Bluesky

JKR struggling to define 'women' like

Aug 9, 2025 · 8 likes · 1 share View post →
Dhiordan Lovestain
@dhiordanlove.bsky.social · Bluesky

A menstruação é um fenômeno raro na natureza! Neste vídeo iremos conhecer quais espécies, além do humano que também menstruam e entender um pouco mais sobre a menstruação

May 17, 2025 · 5 likes · 3 shares View post →
Dhiordan Lovestain
@dhiordanlove.bsky.social · Bluesky

Neste vídeo iremos explorar as origens evolutivas da menstruação e entender pq ela é o resultado não intencional de uma "guerra" entre o útero e o embrião! Vem entender mais sobre a evolução em nós mamíferos

Jun 3, 2025 · 4 likes · 1 share View post →
Simian Seminar
@SimianSeminar · X

Interesting example of adaptationist thinking in human biology. Hyp: menstruation is the byproduct of spontaneous decidualization of the endometrium, which evolved as a line of defense against invasive fetal tissues and/or for embryo selection. https://t.co/fOimY10fqh https://t.co/jGwYlhtyDl

Dec 6, 2022 · 3 likes · 165 followers View post →
Luciana Feliciano | DR em genética
@lumafelic · X

Nos animais que menstruam a gestação é controlada pelo corpo da mãe. Enquanto nos animais de ciclo estral o embrião é que controla as mudanças no útero. https://t.co/razsUcz654

Aug 15, 2021 · 1 like · 2,492 followers View post →

All mentions

the original Aloof Wife
@cpi.pinball.horse · Bluesky

JKR struggling to define 'women' like

Aug 9, 2025 · 8 likes · 1 share View post →
Dhiordan Lovestain
@dhiordanlove.bsky.social · Bluesky

Neste vídeo iremos explorar as origens evolutivas da menstruação e entender pq ela é o resultado não intencional de uma "guerra" entre o útero e o embrião! Vem entender mais sobre a evolução em nós mamíferos

Jun 3, 2025 · 4 likes · 1 share View post →
Dhiordan Lovestain
@DhiordanLove · X

E se você ficou curioso para entender mais sobre como a menstruação funciona e como ela ocorre nas espécies de mamíferos placentários, vem conferir tudo em nosso vídeo: https://t.co/7PsDPED5YW https://t.co/r8iGttIz4u

May 17, 2025 · 32 likes · 33,160 followers View post →
Dhiordan Lovestain
@dhiordanlove.bsky.social · Bluesky

A menstruação é um fenômeno raro na natureza! Neste vídeo iremos conhecer quais espécies, além do humano que também menstruam e entender um pouco mais sobre a menstruação

May 17, 2025 · 5 likes · 3 shares View post →
eg
@erratagnostic · X

@cremieuxrecueil Some cool sources Natural Selection of Human Embryos: Decidualizing Endometrial Stromal Cells Serve as Sensors of Embryo Quality upon Implantation Menstruation: a nonadaptive consequence of uterine evolution The evolution of menstruation: A new model for genetic assimilation

Feb 1, 2024 · 1 like · 82 followers View post →
Maleniya
@untogaandaluz · X

@Otonnia Acá hay otro que habla de la limpieza de los posibles patógenos que traigan los spermas y la asimilación genética del conflicto embrión/madre. Sería como un mecanismo de sorteo del sistema inmune para aceptar al embrión. (?).https://t.co/jaEV6Ju7ic

Jan 28, 2024 · 1 like · 504 followers View post →
bioZone
@thebiozone · X

information sources: Catalini & Fedder (2020). https://t.co/gO69ukfxDn Emera et al. (2012). https://t.co/yYtcGO7WE6 Jarrell (2018). https://t.co/LlSuWwOfbd

Sep 17, 2023 · 186 followers View post →
Simian Seminar
@SimianSeminar · X

Interesting example of adaptationist thinking in human biology. Hyp: menstruation is the byproduct of spontaneous decidualization of the endometrium, which evolved as a line of defense against invasive fetal tissues and/or for embryo selection. https://t.co/fOimY10fqh https://t.co/jGwYlhtyDl

Dec 6, 2022 · 3 likes · 165 followers View post →
Luciana Feliciano | DR em genética
@lumafelic · X

Nos animais que menstruam a gestação é controlada pelo corpo da mãe. Enquanto nos animais de ciclo estral o embrião é que controla as mudanças no útero. https://t.co/razsUcz654

Aug 15, 2021 · 1 like · 2,492 followers View post →
Fucklord Ethelred
@TheRedRaptor · X

@DevoEvoMed This one! https://t.co/Y7NopPRmI7

Apr 20, 2021 · 591 followers View post →
AlexanderCP
@achahuasoncco · X

@ricarparr1 @psecada @mayckel11 @GustavoEscribe Ya llegué a la computadora en donde tengo mi historial, comienzo con el primer paper: The evolution of menstruation: A new model for genetic assimilation https://t.co/JjRvkm8LBe

Nov 7, 2020 · 346 followers View post →
Dr Eva Sweeney
@evamariesweeney · X

Menstruation evolved at least 3 times - primates, bats and the elephant shrew (more closely related to elephants & shrews!), possibly via genetic assimilation, to protect against aggressive embryos & for better embryo selection - interesting read!: https://t.co/dcTDyLCUL9 https://t.co/E88397ztcz

Dec 11, 2019 · 1 like · 380 followers View post →
La Célula de Purkinje
Facebook

https://doi.org/10.1002/bies. 201100099 John Jarrell (2018). The significance and evolution of menstruation. Best Practice & Research Clinical Obstetrics ...

Dec 11, 2025 View →
Menstruation Evolution
News

http://onlinelibrary.wiley.com/doi/10.1002/bies.201100099/pdf; Ferin M, Jewelewicz R, Warren MP. The Menstrual Cycle: Physiology, Reproductive Disorders, and ...

Dec 11, 2025 View →
Evolusi Siklus Haid | PDF | Menstrual Cycle | Implantation (Human ...
News

10.1002/bies.201100099; 10.1002/bies.201100099. Euling, S. Y., Herman-Giddens, M. E., Lee, P. A., Selevan, S. G., Juul, A., Sorensen, T. I., Swan, S. H. ...

Dec 11, 2025 View →
Prevalence of Dysmenorrhea in Girls in Osun State University | PDF ...
News

https://doi.org/10.1002/bies.201100099. Esan, D. T., Ariyo, S. A., Akinlolu, E. F., Akingbade, O., Olabisi, O. I., Olawade, D. B., Bamigboye ...

Jul 23, 2025 View →
Menstrual Cycle - Wikipedia | PDF | Menstrual Cycle | Ovary
News

doi:10.1002/bies.201100099 (https://doi.org/10.1002%2Fbies.201100099) . PMC 3528014 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528014) ...

Jul 18, 2025 View →
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Blogs

... 10.1002/bies.201100099. | Arşiv Bağlantısı; ^ M. Sakata, et al. (1998). A New Artificial Placenta With A Centrifugal Pump: Long-Term Total ...

Feb 24, 2024 View →
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News

doi: 10.1002/bies.201100099. [2]Sferruzzi-Perri, A. N., López-Tello, J., Fowden, A. L., et al. (2016). Maternal and fetal genomes interplay ...

Nov 4, 2022 View →
Is human bipedalism linked to menstruation? : r/AskAnthropology
Reddit

doi:10.1002/bies.201100099. PMC 3528014. PMID 22057551. Bellofiore N, Cousins F, Temple-Smith P, Dickinson H, Evans J (July 2018). "A ...

Mar 9, 2020 View →
Alla däggdjur har inte #mens, och anledningen är att olika arters ...
Facebook

com/doi/full/10.1002/bies.201100099. onlinelibrary.wiley.com. The evolution of menstruation: A new model for genetic assimilation. 7 yrs. Recent ...

Jun 22, 2018 View →
¿Por qué los animales domésticos no tienen la regla? - Naukas
Blogs

doi:10.1002/bies.201100099. Cathérine Dupont M. Chromosomal instability in rhesus macaque preimplantation embryos. Fertility and Sterility ...

Oct 10, 2017 View →
לראשונה, נמצא מחזור וסת במכרסם וסת, הוא תהליך פיסיולוגי-הורמונלי ...
Facebook

המאמר על האבולוציה של מחזור הוסת: http://onlinelibrary.wiley.com/doi/10.1002/bies. 201100099/epdf קראתי לראשונה: http://www.nature.com/news ...

Jun 18, 2016 View →
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Facebook

... 10.1002/bies.201100099/full [3] http://rd.springer.com/article/10.1007/s12110-006-1005-z#page-1 https://www.youtube.com/watch?v=wvcvM4SUgUw ...

Apr 28, 2016 View →
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Reddit

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Apr 18, 2016 View →