PubHawk
PLoS One July 2012 PMID 22389676

Transgenerational actions of environmental compounds on reproductive disease and identification of epigenetic biomarkers of ancestral exposures.

Mohan Manikkam, Carlos Guerrero-Bosagna, Rebecca Tracey, Md M Haque, Michael K Skinner

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Mentions

24
Peak: 5 in Nov 2023
across 6 sources since Apr 2019

Extended reach

20,981
potential audience

Total likes

413

Video views

15,000

Mentions per month

Apr 2019 – Nov 2023

Where it's discussed

  • Facebook12 posts
  • X / Twitter4 posts
  • YouTube2 videos
  • Reddit2 posts
  • News2 articles
  • Blogs2 articles

AI synopsis

What people are saying

The discussions highlight worries about BPA's epigenetic effects and potential transgenerational impacts, with posts raising questions about human exposure and health consequences, especially emphasizing environmental risks, indicating a moderate level of engagement that balances curiosity and concern.

AgreementModerate agreement

The discussions generally acknowledge the importance of the research, with some posts emphasizing the need for caution regarding environmental toxins like BPA.

InterestModerate interest

Participants show moderate interest, asking whether findings apply to humans and contemplating potential health implications.

EngagementNeutral engagement

Comments are somewhat superficial, with some referencing the study and others questioning its relevance, but little in-depth analysis is present.

ImpactModerate impact

The conversations hint at concern about real-world risks and policy implications, suggesting the research could influence public health discussions.

Abstract in brief

  • Environmental compounds like pesticides, plastics, dioxins, and hydrocarbons can cause lasting epigenetic changes in germ cells that are inherited across generations, potentially leading to adult-onset diseases.
  • Exposure during fetal development in pregnant rats led to changes in pubertal timing, reproductive cell health, and ovarian reserves not just in the exposed generation but also in subsequent unexposed generations, especially for plastics, dioxin, and jet fuel.
  • Specific DNA methylation patterns (epigenetic biomarkers) in sperm were identified that are unique to each type of exposure, offering potential tools to trace ancestral environmental contacts linked to health issues later in life.
Read the full abstract

Top posts

Most liked on X and Bluesky
Dr Lucia
@LuciaAronica · X

Should we limit canned food? #BPA in #plastics and #cans can have transgenerational epigenetic effects linked to endocrine disruption in mice: https://t.co/4L6HRNmyaR Could this happen in humans too? Over 90% of us have BPA in their bodies. No panic! Just be smart about it! https://t.co/mrmKggGVsx

Nov 25, 2023 · 7 likes · 2 shares · 1,553 followers View post →
Artem.is #Antifa #NAFO
@GreenWalker92 · X

@Alexis_Verger @jbvioix Manikkam M, Guerrero-Bosagna C, Tracey R, Haque MM, Skinner MK (2012) Transgenerational Actions of Environmental Compounds on Reproductive Disease and Identification of Epigenetic Biomarkers of Ancestral Exposures. PLoS ONE 7(2): e31901. doi:10.1371/journal.pone.0031901

Apr 27, 2019 · 2,205 followers View post →
Andreea Nitescu RD MSc
@AndreeaNRD · X

RT @LuciaAronica: Should we limit canned food? #BPA in #plastics and #cans can have transgenerational epigenetic effects linked to endocr…

Nov 25, 2023 · 2 shares · 1,307 followers View post →
Al Lyman
@_coach_al · X

RT @LuciaAronica: Should we limit canned food? #BPA in #plastics and #cans can have transgenerational epigenetic effects linked to endocr…

Nov 28, 2023 · 2 shares · 905 followers View post →

All mentions

Al Lyman
@_coach_al · X

RT @LuciaAronica: Should we limit canned food? #BPA in #plastics and #cans can have transgenerational epigenetic effects linked to endocr…

Nov 28, 2023 · 2 shares · 905 followers View post →
Andreea Nitescu RD MSc
@AndreeaNRD · X

RT @LuciaAronica: Should we limit canned food? #BPA in #plastics and #cans can have transgenerational epigenetic effects linked to endocr…

Nov 25, 2023 · 2 shares · 1,307 followers View post →
Dr Lucia
@LuciaAronica · X

Should we limit canned food? #BPA in #plastics and #cans can have transgenerational epigenetic effects linked to endocrine disruption in mice: https://t.co/4L6HRNmyaR Could this happen in humans too? Over 90% of us have BPA in their bodies. No panic! Just be smart about it! https://t.co/mrmKggGVsx

Nov 25, 2023 · 7 likes · 2 shares · 1,553 followers View post →
Artem.is #Antifa #NAFO
@GreenWalker92 · X

@Alexis_Verger @jbvioix Manikkam M, Guerrero-Bosagna C, Tracey R, Haque MM, Skinner MK (2012) Transgenerational Actions of Environmental Compounds on Reproductive Disease and Identification of Epigenetic Biomarkers of Ancestral Exposures. PLoS ONE 7(2): e31901. doi:10.1371/journal.pone.0031901

Apr 27, 2019 · 2,205 followers View post →