Overall, the discussions show strong interest and moderate engagement, with users referencing specific concepts like engram activation and related studies, and noting potential for advancing memory research. Words like 'proposed,' 'evidence,' and 'memory activation' highlight curiosity combined with scientific rigor, reflecting both fascination and acknowledgment of the study's importance.
AgreementModerate agreement
Most discussions acknowledge the significance of the study, with some emphasizing its role in understanding memory mechanisms.
InterestHigh interest
Participants demonstrate high interest, referencing related research and implications, which indicates engagement with the topic.
EngagementModerate engagement
Comments include technical explanations and references to other studies, showing active engagement with scientific details.
ImpactModerate impact
Discussions suggest the research could have meaningful implications for neuroscience and memory manipulation, though some see it as a stepping stone.
Abstract in brief
The study used optogenetics to activate specific hippocampal neurons involved in fear memory in mice, demonstrating that stimulating these neurons can trigger the recall of fear (freezing behavior).
The results showed that reactivating neurons tagged during fear learning caused mice to freeze only when the neurons were stimulated with light, confirming that this activation is sufficient to induce fear memory recall in a specific context.
This research suggests that memory recall can be artificially triggered by targeting a small group of neurons encoding that memory, and provides a method for identifying and manipulating memory engrams in the brain.]
Published: 22 March 2012
Optogenetic stimulation of a hippocampal engram activates fear memory recall https://t.co/99NQ7rB6gz https://t.co/Ad0ROuJDyn
Nov 5, 2021 · 8 likes · 5 shares · 9,950 followersView post →
KV
Kunjumon Vadakkan
@KunjVadakkan · X
Engram: A bottom-up approach proposed activated spines clustered on a dendritic branch (https://t.co/2DCBHxlNe8) & a top-down approach reached the engram cells (https://t.co/JZtrwGlQKk). The semblance hypothesis has proposed what is there between the spines and spiking neurons.
Jun 5, 2025 · 4 likes · 1 share · 4,782 followersView post →
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Wanhe Li
@xseedling · X
@caffeinatedcee "Optogenetic stimulation of a hippocampal engram activates fear memory recall" (Liu et al., 2012) "Creating a False Memory in the Hippocampus" (Ramirez., 2013). I think these two papers are the modern neuroscience demonstration of the cellular basis of memory.
This video reviews the process of learning, types of knowledge, and key brain areas involved in processing new information. It discusses how memories are formed, stored, and retrieved, highlighting recent research on…
This video discusses the neuroscience of memory implantation and the possibility of projecting thoughts or dreams onto a screen through the measurement and decoding of brain signals. It offers insights into recent…
RT @KunjVadakkan: Engram: A bottom-up approach proposed activated spines clustered on a dendritic branch (https://t.co/2DCBHxlNe8) & a top-…
Jun 16, 2025 · 1 share · 4,782 followersView post →
KV
Kunjumon Vadakkan
@KunjVadakkan · X
Engram: A bottom-up approach proposed activated spines clustered on a dendritic branch (https://t.co/2DCBHxlNe8) & a top-down approach reached the engram cells (https://t.co/JZtrwGlQKk). The semblance hypothesis has proposed what is there between the spines and spiking neurons.
Jun 5, 2025 · 4 likes · 1 share · 4,782 followersView post →
LL
luca Leli.
@adamoprogresso · X
La stimolazione optogenetica di un engram ippocampale attiva il richiamo della memoria della paura - PubMed https://t.co/YGP96hp25p
Published: 22 March 2012
Optogenetic stimulation of a hippocampal engram activates fear memory recall https://t.co/99NQ7rB6gz https://t.co/Ad0ROuJDyn
Nov 5, 2021 · 8 likes · 5 shares · 9,950 followersView post →
OP
Odysseus living with Penelope
@immuno458 · X
@GABOERGICO @MONTEROCANAE @miltonmuriIIo @mcvergara21 Y se puede evidenciar de como se activa toda una vía de miedo a partir de estimular las neuronas que desde el hipotalamo (memoria) desencadenan el proceso. Recordar es vivir. https://t.co/zN1XW0Ajix 12/n
@caffeinatedcee "Optogenetic stimulation of a hippocampal engram activates fear memory recall" (Liu et al., 2012) "Creating a False Memory in the Hippocampus" (Ramirez., 2013). I think these two papers are the modern neuroscience demonstration of the cellular basis of memory.
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https://www.nature.com/articles/nature11028 המחקר הראשון בעולם שהראה הפעלה של זיכרון פחד באור 2. ... 10.1038/s43016-024-00987-3 * מאמר על האיום האקלימי על עצי ...
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... 10.1038/s43016-024-00987-3 * מאמר על האיום האקלימי על עצי הקקאו ... https://www.nature.com/articles/nature11028 המחקר הראשון בעולם שהראה הפעלה של ...
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... 10.1038/s43016-024-00987-3 * מאמר על האיום האקלימי על עצי הקקאו ... https://www.nature.com/articles/nature11028 המחקר הראשון בעולם שהראה הפעלה של ...
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... 10.1038/s43016-024-00987-3 * מאמר על האיום האקלימי על עצי הקקאו ... https://www.nature.com/articles/nature11028 המחקר הראשון בעולם שהראה הפעלה של ...
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