January 2013 PMID 22746245

Microdose lithium treatment stabilized cognitive impairment in patients with Alzheimer's disease.

Marielza Andrade Nunes, Tania Araujo Viel, Hudson Sousa Buck

Download social card

Mentions

32
Peak: 5 in Aug 2025
across 6 sources since Jan 2020

Extended reach

360,836
potential audience

Total likes

3,920

Video views

77,594

Mentions per month

Jan 2020 – Aug 2025

Where it's discussed

  • X / Twitter16 posts
  • Facebook5 posts
  • News4 articles
  • Bluesky3 posts
  • YouTube2 videos
  • Blogs2 articles

AI synopsis

What people are saying

Posts frequently support the research, citing specific studies from 2013 and mentioning how microdosing lithium could be neuroprotective, with language reflecting curiosity and optimism. The tone varies from supportive to questioning, illustrating both engagement and recognition of potential impact.

AgreementModerate agreement

Most discussions express support or interest in the findings, with some questioning the broader implications, indicating general agreement.

InterestHigh interest

A high number of posts reference personal experiences, historical research, or potential applications, showing strong interest.

EngagementModerate engagement

Participants cite studies, suggest further research, and debate implications, demonstrating active engagement.

ImpactModerate impact

Posts suggest that the findings could influence future research or medical practices, though some question its current relevance, indicating moderate impact.

Abstract in brief

  • Microdose lithium treatment at 300 micrograms daily helped stabilize cognitive function in Alzheimer's patients over 15 months, with the treated group maintaining their mental performance while the control group declined.
  • Lithium is known to reduce dementia risk in bipolar patients by inhibiting pathways related to amyloid buildup and tau protein hyperphosphorylation, which are involved in Alzheimer's disease.
  • Using very low doses of lithium (microdoses) may offer a safe and effective way to prevent or slow Alzheimer's without the toxicity associated with higher doses.]

Top posts

Most liked on X and Bluesky
Steven Phillips, MD
@StevePhillipsMD · X

2/5 I started putting patients on over-the-counter low dose lithium in 2013 when I read that even micro-dosing can be neuroprotective. https://t.co/6vNYSK5snf

Mar 18, 2022 · 17 likes · 1 share · 82,893 followers View post →
Agingdoc
@agingdoc1 · X

Microdose Lithium Treatment Stabilized Cognitive Impairment in Patients with Alzheimer's Disease https://t.co/H3odEFrMn9

Dec 6, 2022 · 13 likes · 41,325 followers View post →
Adam Bataineh MD
@DrAdamBat · X

Lithium 400 ug prevents alzheimers progression completely in a 1.5 year RCT https://t.co/JaZibj3pe9 https://t.co/ScEVL3KgIO

Dec 4, 2021 · 9 likes · 43,069 followers View post →
Jon Brudvig
@jonbrudvig.bsky.social · Bluesky

Key sources 2:

Aug 21, 2025 · 7 likes · 4 shares View post →
Nick Norwitz MD PhD
@nicknorwitz · X

Fact of day 187: Microdose lithium (over the counter) may inhibit the GSK3B protein that contributes to #Alzhiemers disease https://t.co/JgrkTJzLS7 https://t.co/KXse6az86G

Aug 22, 2020 · 4 likes · 108,830 followers View post →
robi sen
@robi_sen · X

This is fascinating -- Microdose lithium treatment stabilized cognitive impairment in patients with Alzheimer's disease. - PubMed - NCBI https://t.co/l5cHe4GFuG

Jan 29, 2020 · 2 likes · 1 share · 1,104 followers View post →

All mentions

Jon Brudvig
@jonbrudvig.bsky.social · Bluesky

Key sources 2:

Aug 21, 2025 · 7 likes · 4 shares View post →
Mi lado B
@nocreasanadie.bsky.social · Bluesky

pero en la Discusión del paper dice "Li at lower concentrations (0.25–0.5 mEq l−1 in serum) reduced cognitive decline", citando varios trabajos, entre ellos "Microdose lithium treatment stabilized cognitive impairment in patients with Alzheimer’s disease" de 2013... sigue

Aug 10, 2025 · 1 share View post →
Mace Moneta
@macemoneta.bsky.social · Bluesky

First paper I found - from 2013 - recognized this. pubmed.ncbi.nlm.nih.gov/22746245/

Aug 8, 2025 View post →
Clean Energy Ultd.
@progress_ultd · X

@DanClintonRN Lmao https://t.co/Qw4GckBkzH

Feb 10, 2025 · 1 like · 570 followers View post →
Xenon-NtrκB
@gyc1663642 · X

RT @PiracetamNET: I just posted "Microdose lithium treatment stabilized cognitive impairment in patients with Alzheimer's disease" on Reddi…

Nov 26, 2023 · 1 share · 15 followers View post →
Xenon-NtrκB
@gyc1663642 · X

RT @PiracetamNET: I just posted "Microdose lithium treatment stabilized cognitive impairment in patients with Alzheimer's disease" on Reddi…

Nov 26, 2023 · 1 share · 15 followers View post →
St. Augustine's Fountain
@Aquilegy · X

A study tested lithium at nutritional volumes versus placebo in a 15-month study of patients with mild cognitive impairment. Those taking nutritional lithium exhibited stable memory test scoring while placebo group scores significantly declined. https://t.co/WT3k07e5fJ

Jun 8, 2023 · 192 followers View post →
Piracetam.Net
@PiracetamNET · X

I just posted "Microdose lithium treatment stabilized cognitive impairment in patients with Alzheimer's disease" on Reddit https://t.co/O7unmFeOGd

Apr 9, 2023 · 1 like · 1 share · 78 followers View post →
Agingdoc
@agingdoc1 · X

Microdose Lithium Treatment Stabilized Cognitive Impairment in Patients with Alzheimer's Disease https://t.co/H3odEFrMn9

Dec 6, 2022 · 13 likes · 41,325 followers View post →
Daniel Grimaldes MD
@DrGrimaldesJ · X

or as a way to reduce the risk of Alzheimer's disease and other neurodegenerative diseases https://t.co/y265avYOuZ https://t.co/aIqN55lwdF https://t.co/mBB3WHwWLM

Oct 4, 2022 · 2 likes · 1,011 followers View post →
Oregon Deb
@Debbiem51488829 · X

This paper shows a date of 2013. Has there been more testing? Is big pharma, the CDC, or NIH just ignoring the potential of Lithium treatment because there's no money to be made? https://t.co/Ts41KaVbTA

Aug 13, 2022 · 402 followers View post →
Piracetam.Net
@PiracetamNET · X

I just posted "Microdose lithium treatment stabilized cognitive impairment in patients with Alzheimer's disease" on Reddit https://t.co/dnQobFdHGf

Aug 13, 2022 · 1 like · 1 share · 78 followers View post →
scriabina
@drschumann1 · X

Interesting. I'd like to see an RCT in patients with post-COVID cognitive dysfunction on lithium at various serum target levels vs placebo. I wonder if or what lithium levels might protect covid pts from reduced gray matter, "brain fog," etc. https://t.co/KCffss4P6F

Mar 19, 2022 · 1 like · 198 followers View post →
lateafternoon_k
@lateafternoon_k · X

RT @StevePhillipsMD: 2/5 I started putting patients on over-the-counter low dose lithium in 2013 when I read that even micro-dosing can be…

Mar 18, 2022 · 1 share · 557 followers View post →
Steven Phillips, MD
@StevePhillipsMD · X

2/5 I started putting patients on over-the-counter low dose lithium in 2013 when I read that even micro-dosing can be neuroprotective. https://t.co/6vNYSK5snf

Mar 18, 2022 · 17 likes · 1 share · 82,893 followers View post →
Adam Bataineh MD
@DrAdamBat · X

Lithium 400 ug prevents alzheimers progression completely in a 1.5 year RCT https://t.co/JaZibj3pe9 https://t.co/ScEVL3KgIO

Dec 4, 2021 · 9 likes · 43,069 followers View post →
Nick Norwitz MD PhD
@nicknorwitz · X

Fact of day 187: Microdose lithium (over the counter) may inhibit the GSK3B protein that contributes to #Alzhiemers disease https://t.co/JgrkTJzLS7 https://t.co/KXse6az86G

Aug 22, 2020 · 4 likes · 108,830 followers View post →
Slicin' Hammer ⚠️
@SlicinHammer · X

RT @robi_sen: This is fascinating -- Microdose lithium treatment stabilized cognitive impairment in patients with Alzheimer's disease. - Pu…

Jan 29, 2020 · 1 share · 2,880 followers View post →
robi sen
@robi_sen · X

This is fascinating -- Microdose lithium treatment stabilized cognitive impairment in patients with Alzheimer's disease. - PubMed - NCBI https://t.co/l5cHe4GFuG

Jan 29, 2020 · 2 likes · 1 share · 1,104 followers View post →