November 2012 PMID 22844412

Effect of short-term thyroxine administration on energy metabolism and mitochondrial efficiency in humans.

Darcy L Johannsen, Jose E Galgani, Neil M Johannsen, Zhengyu Zhang, Jeffrey D Covington, Eric Ravussin

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Mentions

10
Peak: 9 in Jan 2025
across 2 sources since Mar 2024

Extended reach

44,475
potential audience

Total likes

1,006

Video views

43,256

Mentions per month

Mar 2024 – Feb 2025

Where it's discussed

  • YouTube9 videos
  • X / Twitter1 posts

AI synopsis

What people are saying

This discussion reflects personal intrigue about how thyroid hormone adjustments could explain weight loss, using phrases like 'how I'm losing weight with no effort' and acknowledging the potential significance of a 4% increase in BMR. The tone combines curiosity and practical interest, highlighting a moderate impact on individual health understanding.

AgreementModerate agreement

The post agrees with the article's notion that thyroid hormone levels influence metabolism, viewing it as a plausible explanation for weight loss without effort.

InterestModerate interest

The discussion shows curiosity about practical implications of the research, particularly relating to weight management.

EngagementNeutral engagement

The comment is casual and reflects initial insight, but it doesn't delve into detailed scientific analysis.

ImpactModerate impact

The post suggests a moderate recognition of the article's relevance to everyday weight concerns, hinting at personal relevance but not broad scientific impact.

Abstract in brief

  • Short-term T4 supplementation for 3 days slightly increases resting metabolic rate by about 4%, but doesn't affect energy use during exercise.
  • T4 reduces skeletal muscle mitochondrial efficiency by roughly 30%, decreasing the muscle's ability to produce ATP effectively.
  • Overall, T4 appears to modestly boost resting metabolism and decrease mitochondrial efficiency in muscles, which could have implications for its use in treating obesity and other non-thyroidal conditions.]

Top posts

Most liked on X and Bluesky
God's Gift to Warthogs
@CarlOrkmansen · X

Still kind of puzzled by how I'm losing weight with no effort, but now seeing that fixing thyroid hormone levels thru levothyroxine can increase BMR by 4%! That will do it. https://t.co/Vphlv9J7iM

Mar 28, 2024 · 1,222 followers View post →

All mentions

God's Gift to Warthogs
@CarlOrkmansen · X

Still kind of puzzled by how I'm losing weight with no effort, but now seeing that fixing thyroid hormone levels thru levothyroxine can increase BMR by 4%! That will do it. https://t.co/Vphlv9J7iM

Mar 28, 2024 · 1,222 followers View post →