A systematic review and meta-analysis of clinical trials investigating obesity management medications reports that tirzepatide and semaglutide are the most effective in reducing body weight and obesity-related complications, according to a paper in Nature Medicine. #medsky
Systematic review and meta-analysis of clinical trials of the effects of low carbohydrate diets on cardiovascular risk factors.
Mentions
Extended reach
Total likes
Video views
Mentions per month
Apr 2019 – Oct 2025Where it's discussed
-
Facebook57 posts
-
News39 articles
-
X / Twitter30 posts
-
Blogs14 articles
-
Bluesky9 posts
-
YouTube3 videos
AI synopsis
What people are saying
The discussions demonstrate strong interest and engagement by highlighting specific health benefits of low carb diets, such as lowering blood pressure and triglycerides, and referencing detailed results, but many also acknowledge ongoing debates about long-term impacts, which tempers the perceived overall influence of the publication.
Most discussions recognize the findings of the review, with some emphasizing benefits like reduced blood pressure and cardiovascular risk factors.
The discussions express high interest by focusing on specific health markers, diet types, and implications, showing participants find the topic relevant.
People reference detailed outcomes, such as reductions in triglycerides and blood pressure, and debate methodological issues, indicating deep engagement.
While some posts highlight potential health improvements, the overall impact seems moderate, as debates include uncertainties about long-term effects and conflicting evidence.
Abstract in brief
- This systematic review and meta-analysis examined 17 clinical trials involving 1,141 obese patients to evaluate how low-carbohydrate diets (LCD) affect weight and cardiovascular risk factors.
- The results indicated that LCDs significantly improved various health markers, including reductions in body weight, BMI, abdominal circumference, blood pressure, triglycerides, fasting glucose, glycated hemoglobin, plasma insulin, and C-reactive protein, while increasing HDL cholesterol; LDL cholesterol and creatinine levels remained unchanged.
- Although LCDs showed promising short-term benefits for weight loss and cardiovascular health, the long-term effects on overall health are still uncertain due to limited data.]
Top posts
Most liked on X and BlueskyLow carb diets reduce body weight, body mass index, abdominal circumference, blood pressure, triglycerides, fasting plasma glucose, glycated haemoglobin, plasma insulin, plasma C-reactive protein, and increase HDL
@EricTopol @CellCellPress @PTurnbaugh @DrKristaVarady It's premature to claim keto increases CVD. There's simply no long term quality evidence to evaluate https://t.co/OQUAoKGvrA https://t.co/K3WcQq4HuW https://t.co/zwv4VireUg https://t.co/02koCqbgpd But short term trial evidence is clear: keto improves health and decreases CVD risk
@Malelo2711 @mauriciomezomo @lsdefraga @TaschnerNatalia @hungryeyebrows @AJKowaltowski Sim, o texto (não é dela) está factualmente errado: https://t.co/1czVqKLFh0 Mas veja, ñ era esse o ponto do tweet. O ponto dela eram os graves efeitos deletérios sobre autoestima dos adolescentes causados p/ esses influenciadores digitais - o Instagram, de fato, faz mal à saúde
@moreyraortho https://t.co/o9QCgGXeMp
Referencias: https://t.co/VAuzW6MQQg https://t.co/VJLl0UF9tu https://t.co/fU5AJqOOJO https://t.co/mGF7SdiMdV https://t.co/xNqtpQnirj https://t.co/oZHp1EKU1C https://t.co/lAMDr4vjxb https://t.co/DQeMsjP0oH https://t.co/pdw0C4m9mL
All mentions
Effective Methods to Lower Blood Pressure Naturally and Quickly
This video demonstrates three simple ways to lower blood pressure, including breathing techniques, isometric exercises, and addressing root causes such as metabolic disease to improve overall cardiovascular health.
Game changer - Désinformation ? Exagération ?
Impact of Low-Carbohydrate Diets on Weight and Cardiovascular Risks
This systematic review and meta-analysis examined 17 clinical trials involving 1,141 obese patients to evaluate how low-carbohydrate diets affect weight and cardiovascular risk factors. Results showed significant…
Jak działa dieta niskowęglowodanowa? Prawda, o której nikt nie mówi
Effects of Low-Carb Diets on Health and Metabolic Benefits
This week, we explore the low-carbohydrate diet which can offer metabolic benefits, especially for those with diabetes or at risk. We analyze weight loss, lipid levels, and discuss various diet plans including Atkins…
A systematic review and meta-analysis of clinical trials investigating obesity management medications reports that tirzepatide and semaglutide are the most effective in reducing body weight and obesity-related complications, according to a paper in Nature Medicine. #medsky
Predicting epilepsy in patients diagnosed with intracranial meningiomas: A systematic review and meta-analysis of clinical and anatomical risk factors
The effects of silymarin supplementation on metabolic status and oxidative stress in patients with type 2 diabetes mellitus: A systematic review and meta-analysis of clinical trials.
Cognitive-behavioural therapy (CBT) for outpatients with anorexia nervosa: a systematic review and meta-analysis of clinical effectiveness
Placebo and Nocebo Responses in Multiple System Atrophy - a systematic review and meta-analysis of clinical trials https://www.medrxiv.org/content/10.1101/2024.11.05.24316747v1
@ElaineVigneault https://t.co/XNx9l2OtAV Low carb lowered CVD risk independent of weight loss https://t.co/zwv4ViqH4I Low carb improves blood pressure, trigs, glucose, a1c, insulin, CRP, & HDL https://t.co/OQUAoKFXC2 Keto resulted in 11.9% reduction in ASCVD risk score
@RogerSeheult https://t.co/mNl98pflJL No RCT evidence that changes in LDLc via diet affect CVD or mortality https://t.co/rDol9781Sr https://t.co/vReWVdvjLr https://t.co/KlkVCONLLL MA of RCTs show no effects from meat https://t.co/zwv4VireUg High meat low carb diets improve metabolic health
@NutritionMadeS3 Short term RCTs: carb restriction lowers systolic bp by 4.81 mmHg & diastolic bp by 3.10 mmHg. https://t.co/zwv4VireUg High insulin -> high sodium retention, regardless of sodium intake. https://t.co/fiU6p0DERK Keto reduced systolic bp more than DASH after 4 months
Mitigating the Opioid Epidemic: The Role of Cannabinoids in Chronic Pain Management - A Systematic Review and Meta-Analysis of Clinical Evidence and Mechanisms https://www.medrxiv.org/content/10.1101/2024.07.14.24310378v1
@EricTopol @CellCellPress @PTurnbaugh @DrKristaVarady It's premature to claim keto increases CVD. There's simply no long term quality evidence to evaluate https://t.co/OQUAoKGvrA https://t.co/K3WcQq4HuW https://t.co/zwv4VireUg https://t.co/02koCqbgpd But short term trial evidence is clear: keto improves health and decreases CVD risk
@triagemethod @stathi_ Even low carb (not strictly keto) reduces blood pressure. SR of clinical trials: low carb reduced systolic blood pressure by 4.81 mm Hg and diastolic blood pressure by 3.10 mm Hg https://t.co/zwv4ViqH4I
Multidisciplinary inpatient rehabilitation for older adults with COVID-19: a systematic review and meta-analysis of clinical and process outcomes. BMC Geriatr 2023 2/5
Systematic review and meta-analysis of clinical trials of the effects of low carbohydrate diets on cardiovascular risk factors https://t.co/piFqMvnzMj https://t.co/SKEwI3VflW
@LMiliu @Yo_soy_JulyR Por ejemplo? https://t.co/911rp3uxIi
@TomaszLaszcz @Kamil_Paprotny @DrKermitHouse ale jakie to ma znaczenie, jaki bedzie LDL (choc są badania, ktore mowią, że nie podnosi), skoro z badan wynika, że diety niskoweglowodanowe nie zwiekszaja ryzyka chorbo sercowo-naczyniowych, a wręcz przeciwnie? https://t.co/xTlh2O8pmv
@JuhaniKnuuti Ja koska olet mahdollisesti niin boomer, ettet vain tajua, niin tässä vielä kerran. https://t.co/gv7SBig2rv
@JuhaniKnuuti Systematic review and meta-analysis of clinical trials of the effects of low carbohydrate diets on cardiovascular risk factors. Katso tuo aiempi, vai etkö osaa käyttää edes twitteriä
@JuhaniKnuuti Mikä siinä on niin vaikeaa? https://t.co/gv7SBig2rv
@MnicaOl66576715 Referencias: https://t.co/AYO5ooILzZ https://t.co/Gnxw3a408S https://t.co/V0vrkEnsF6 https://t.co/Ungvpil14n https://t.co/v82ohQTq5S https://t.co/2LE1SKQTyt https://t.co/lAMDr4vjxb https://t.co/XIUDC3T8ed https://t.co/30WkXJVgLP
@DenilsonFAraujo Referencias: https://t.co/AYO5ooILzZ https://t.co/Gnxw3a408S https://t.co/V0vrkEnsF6 https://t.co/Ungvpil14n https://t.co/v82ohQTq5S https://t.co/2LE1SKQTyt https://t.co/lAMDr4vjxb https://t.co/XIUDC3T8ed https://t.co/30WkXJVgLP
@MaxBearzi Referencias: https://t.co/AYO5ooILzZ https://t.co/Gnxw3a408S https://t.co/V0vrkEnsF6 https://t.co/Ungvpil14n https://t.co/v82ohQTq5S https://t.co/2LE1SKQTyt https://t.co/lAMDr4vjxb https://t.co/XIUDC3T8ed https://t.co/30WkXJVgLP
Referencias: https://t.co/VAuzW6MQQg https://t.co/VJLl0UF9tu https://t.co/fU5AJqOOJO https://t.co/mGF7SdiMdV https://t.co/xNqtpQnirj https://t.co/oZHp1EKU1C https://t.co/lAMDr4vjxb https://t.co/DQeMsjP0oH https://t.co/pdw0C4m9mL
F L Santos et al. Obes Rev. 2012 Systematic review and meta-analysis of clinical trials of the effects of low carbohydrate diets on cardiovascular risk factors
@engwaiong @ScepticalDoctor @dr_cois https://t.co/OeHWlhuVZa
@Malelo2711 @mauriciomezomo @lsdefraga @TaschnerNatalia @hungryeyebrows @AJKowaltowski Sim, o texto (não é dela) está factualmente errado: https://t.co/1czVqKLFh0 Mas veja, ñ era esse o ponto do tweet. O ponto dela eram os graves efeitos deletérios sobre autoestima dos adolescentes causados p/ esses influenciadores digitais - o Instagram, de fato, faz mal à saúde
@theproof @DominicDAgosti2 ▪️ though a number of RCTs do show increased LDL-c with LC, which may be due to #LMHR or it may indeed be ⬆️ risk for ASVD. We don't know. Also, here's a systematic review & meta-analysis of 17 RCTs - image below shows the benefits of LC compared to LF
@Uri85_ @_Punhal_ Además mejoran el control de glucosa. https://t.co/iVP06yXqjJ El síndrome metabólico: https://t.co/YvraUkCIAd Los triglicéridos: https://t.co/XX4R3fnngQ Etc etc etc.
RT @DiscoStew66: Low carb diets reduce body weight, body mass index, abdominal circumference, blood pressure, triglycerides, fasting plasma…
Low carb diets reduce body weight, body mass index, abdominal circumference, blood pressure, triglycerides, fasting plasma glucose, glycated haemoglobin, plasma insulin, plasma C-reactive protein, and increase HDL
Effect of Coffee Consumption on Renal Outcome: A Systematic Review and Meta-Analysis of Clinical Studies https://www.jrnjournal.org/article/S1051-2276(20)30209-0/fulltext#.YDF1fzEb5lt.twitter
RT @phantaszjia: Systematic review and meta‐analysis of clinical trials of the effects of low carbohydrate diets on cardiovascular risk fac…
Systematic review and meta‐analysis of clinical trials of the effects of low carbohydrate diets on cardiovascular risk factors https://t.co/IAhiQbxqbH
@TheEsteemedFox @AndreaLynnLewis https://t.co/AL4n6ESNKC
https://t.co/g0z2q33Ckd
@moreyraortho https://t.co/o9QCgGXeMp
@NutritionMadeS3 @EAllen0417 @smac121 This meta-analysis of LCHF appears to show reductions in cardiovascular risk factors https://t.co/25HeZEVLEF And here, as an effective treatment of diabetes https://t.co/Aih0WPnZPb What might be the criticisms of such points of evidence that would rule them out as advisable?
Santos FL, et al. Systematic review and meta-analysis of clinical trials of the effects of low carbohydrate diets on cardiovascular risk factors. Obes Rev. 2012;13(11):1048-66.