September 2012 PMID 22943444

Systematic review with meta-analysis of the epidemiological evidence in the 1900s relating smoking to lung cancer.

Peter N Lee, Barbara A Forey, Katharine J Coombs

Download social card

Mentions

46
Peak: 4 in Mar 2024
across 5 sources since Jan 2019

Extended reach

211,558
potential audience

Total likes

942

Video views

25,479

Mentions per month

Jan 2019 – Apr 2025

Where it's discussed

  • X / Twitter31 posts
  • News9 articles
  • YouTube2 videos
  • Facebook2 posts
  • Blogs2 articles

AI synopsis

What people are saying

The discussions reflect strong agreement, with posts emphasizing the consistency of the meta-analysis findings about smoking and lung cancer, using words like 'robust' and 'strong association.' The tone is analytical and cites specific research, demonstrating deep engagement and recognition of the review's impact, despite some disagreements over methodological details and interpretation of statistical significance.

AgreementModerate agreement

Most discussions acknowledge the strong link between smoking and lung cancer, emphasizing the robustness of the meta-analysis findings.

InterestHigh interest

Posts display high interest by referencing specific studies, data, and methodological details, showing engagement with the topic.

EngagementModerate engagement

The discussions involve detailed arguments about study designs, causality, and statistical validity, indicating active engagement.

ImpactModerate impact

Participants recognize the significance of systematic reviews in shaping understanding of smoking-related cancer risks, though some debates suggest varying interpretations.

Abstract in brief

  • This systematic review and meta-analysis examined the relationship between smoking and lung cancer in studies published before 2000, analyzing data from 287 epidemiological studies to quantify risk differences among various smoking types, histological lung cancer subtypes, and demographic groups.
  • The findings showed that smoking significantly increases lung cancer risk, with the strongest effects observed in current smokers, particularly for squamous cell carcinoma, and slightly higher risks in males and in North America, while the risk was lower in Asian populations; the risk estimates varied depending on study design and other factors but consistently indicated a clear association.
  • Interestingly, the review found no increased lung cancer risk for smokers who only smoked pipes or cigars and noted that risks did not differ based on mentholation, although risk levels were generally higher for studies with larger samples or those initiated later, emphasizing a robust link between smoking and lung cancer across different contexts.]

Top posts

Most liked on X and Bluesky
John Gillespie
@DrGillespie_GP · X

@Pl4ntbased According to @realDaveFeldman 's logic- does that mean he thinks the existance of some studies that do not show a significant association of Lung Ca with smoking therefore means that there is no causal relationship? https://t.co/OWzB4dThYJ https://t.co/T5WEMuAnBj

Apr 27, 2025 · 21 likes · 4 shares · 1,067 followers View post →
John Gillespie
@DrGillespie_GP · X

@Gearoidmuar @ScepticalDoctor Imagine if one were to cherrypick Daveys' study from the 1930s to claim that its odd that smoking appeared not to have a significant effect on lung cancer. That would obviously be a nonsensical argument given the results of other studies. https://t.co/PpS60aEB5T https://t.co/OhDLOpuLfh

Feb 26, 2022 · 14 likes · 2 shares · 1,067 followers View post →
چوہدری محبوب اوجلہ
@oldpakistani310 · X

@DrMohammadFaro4 پھر وہی بات ۔ میں نے لٹریچر مانگا ہے۔ ذاتی راۓ نہیں میں systematic review with meta analysis شئیر کر رہا ہوں۔ اگر سمجھ آ جاۓ تو ٹھیک ہے ورنہ پلیز اپنی ذاتی راۓ جو سائینس کا نام نہ دیں۔ شکریہ https://t.co/myDJmoKgE9

Mar 25, 2024 · 4 likes · 3 shares · 7,356 followers View post →
MOOKIE ⌨️
@amir966sam · X

https://t.co/9EfbDiGmjw https://t.co/VLsfVkH52j

Apr 8, 2023 · 4 likes · 355 followers View post →
Atomsk's Sanakan
@AtomsksSanakan · X

@gjbangar @kmpClimate @JaggerMickOZ @badmoonrising11 @StormSignalSA @PolAnimalAus @RoyPentland @Elizabe90736128 @jamieswilson @KCTaz @MLBinWA @EddyKurrents @miked194765 @priscian @seancunnion @HughAbercrombi3 @ag4slip @novakglobal @riktheozfrog @EngineerEarth @RegimeChangeBC @NotLineker @doctorjackpine @ejwwest @SylviaD32911201 @FraserMacLeod5 @craigthomler @Tokyo_Tom @ClimatismBlog @RJinBaltimore @JdavisWx @sueytonius @brandonrgates @JWSpry @Conserv00301750 @lyndoes @txtrue @munungus @caerbannog666 @maralago_ @msroberts0619 @PoeBrianL @flyonthewall182 @BradSchrag @Tangomitteckel @realiwasframed @JamesDe34061167 @Schmoop0521 @try2golf @Pandeism Re: "No one uses 2 sigma as a valid statistical result." You're either willfully ignorant or dishonest. Either way, it's quite telling that you resorted to such a blatantly false claim to justify your willful evasion of evidence. https://t.co/5Z

Jan 16, 2019 · 2 likes · 3,360 followers View post →
АминаЗина
@2204Za · X

@jinnieakgay @Mighty_Lich @milleniumgray Мета-анализ о курении и риске рака легких: https://t.co/ZkaLhnad2o То же, но по раку груди: https://t.co/8qxdjmEOFf Курение и рак полости рта: https://t.co/HdVC18a5kD Везде значительное увеличение рисков. Гуглится на раз-два. Не транслируйте опасные заблуждения

Jan 21, 2024 · 2 likes · 44 followers View post →

All mentions

Rx Readmore Livemore
@SopitaSirirata1 · X

RT @DrGillespie_GP: @Pl4ntbased According to @realDaveFeldman 's logic- does that mean he thinks the existance of some studies that do no…

Apr 28, 2025 · 4 shares · 178 followers View post →
Stevey
@Steveyof3IR3 · X

RT @DrGillespie_GP: @Pl4ntbased According to @realDaveFeldman 's logic- does that mean he thinks the existance of some studies that do no…

Apr 27, 2025 · 4 shares · 1,230 followers View post →
Veganella
@Veganella_ · X

RT @DrGillespie_GP: @Pl4ntbased According to @realDaveFeldman 's logic- does that mean he thinks the existance of some studies that do no…

Apr 27, 2025 · 4 shares · 58,454 followers View post →
John Gillespie
@DrGillespie_GP · X

@Pl4ntbased According to @realDaveFeldman 's logic- does that mean he thinks the existance of some studies that do not show a significant association of Lung Ca with smoking therefore means that there is no causal relationship? https://t.co/OWzB4dThYJ https://t.co/T5WEMuAnBj

Apr 27, 2025 · 21 likes · 4 shares · 1,067 followers View post →
Aaron Lepeska
@AaronLepeska · X

@upRootNutrition @_eleanorina @dylanarmbruste3 Or even worse, they’re unadjusted case-control studies…I have this meta in my cloud drive that’s mostly CC studies with a few poorly-adjusted cohort studies, yet it’s probably among the best evidence we have https://t.co/emSFU6G2KQ https://t.co/L755KKnjTn

Jan 19, 2025 · 1 like · 189 followers View post →
Mambo Number 6
@withered_haze · X

@tommyspianocor1 @saraheeberry The smoking example does speak for itself. When you look at meta analyses, for example this one, they say “the association of lung cancer with smoking is strong”. So, by your logic the causality isn’t proven, yes? https://t.co/EmypGroW5m

Jul 27, 2024 · 68 followers View post →
Shilisad
@Shilisad1 · X

@JulieRei @BobWhencer Put the following in Google. Systematic review with meta-analysis of the epidemiological evidence in the 1900s relating smoking to lung cancer Peter N Lee et al. BMC Cancer. 2012

Apr 12, 2024 · 1,169 followers View post →
Shilisad
@Shilisad1 · X

@JulieRei @BobWhencer Systematic review with meta-analysis of the epidemiological evidence in the 1900s relating smoking to lung cancer Peter N Lee et al. BMC Cancer. 2012.

Apr 12, 2024 · 1 like · 1,169 followers View post →
BM worrier
@hussainabi15474 · X

RT @oldpakistani310: @DrMohammadFaro4 پھر وہی بات ۔ میں نے لٹریچر مانگا ہے۔ ذاتی راۓ نہیں میں systematic review with meta analysis شئیر کر…

Mar 25, 2024 · 3 shares · 575 followers View post →
Prime Pharmacy & Diagnostic
@PrimeFondation · X

RT @oldpakistani310: @DrMohammadFaro4 پھر وہی بات ۔ میں نے لٹریچر مانگا ہے۔ ذاتی راۓ نہیں میں systematic review with meta analysis شئیر کر…

Mar 25, 2024 · 3 shares · 315 followers View post →
Saima Umair
@Saimasartlounge · X

RT @oldpakistani310: @DrMohammadFaro4 پھر وہی بات ۔ میں نے لٹریچر مانگا ہے۔ ذاتی راۓ نہیں میں systematic review with meta analysis شئیر کر…

Mar 25, 2024 · 3 shares · 3,504 followers View post →
چوہدری محبوب اوجلہ
@oldpakistani310 · X

@DrMohammadFaro4 پھر وہی بات ۔ میں نے لٹریچر مانگا ہے۔ ذاتی راۓ نہیں میں systematic review with meta analysis شئیر کر رہا ہوں۔ اگر سمجھ آ جاۓ تو ٹھیک ہے ورنہ پلیز اپنی ذاتی راۓ جو سائینس کا نام نہ دیں۔ شکریہ https://t.co/myDJmoKgE9

Mar 25, 2024 · 4 likes · 3 shares · 7,356 followers View post →
АминаЗина
@2204Za · X

@jinnieakgay @Mighty_Lich @milleniumgray Мета-анализ о курении и риске рака легких: https://t.co/ZkaLhnad2o То же, но по раку груди: https://t.co/8qxdjmEOFf Курение и рак полости рта: https://t.co/HdVC18a5kD Везде значительное увеличение рисков. Гуглится на раз-два. Не транслируйте опасные заблуждения

Jan 21, 2024 · 2 likes · 44 followers View post →
Cardamomo
@Carda_momo_ · X

@Kaden_JRodgers @Aristos_Revenge @LetDaSinkIn That’s the point of meta analyses & systematic reviews. Any 1 paper can be fabricated, but for this systematic review to be a con, it would require a majority of the authors of the 287 included papers (over decades, in multiple countries) to be in on it. https://t.co/wijwZG6p7Q

Dec 20, 2023 · 224 followers View post →
MOOKIE ⌨️
@amir966sam · X

https://t.co/9EfbDiGmjw https://t.co/VLsfVkH52j

Apr 8, 2023 · 4 likes · 355 followers View post →
Tellit Likeitis
@Tellit007 · X

@vegansince96 @robthomas1377 @nutrition_facts Ok I'll bite. Show me anything close to this meta analysis on smoking and cancer with causal inference between meat or fish and cancer. https://t.co/FFFfrlWcEJ

Oct 11, 2022 · 156 followers View post →
A. River
@coalhoof · X

RT @JohnG_UK: @Gearoidmuar @ScepticalDoctor Imagine if one were to cherrypick Daveys' study from the 1930s to claim that its odd that smoki…

Feb 26, 2022 · 2 shares · 1,473 followers View post →
galaxysplain
@galaxysplain · X

RT @JohnG_UK: @Gearoidmuar @ScepticalDoctor Imagine if one were to cherrypick Daveys' study from the 1930s to claim that its odd that smoki…

Feb 26, 2022 · 2 shares · 490 followers View post →
John Gillespie
@DrGillespie_GP · X

@Gearoidmuar @ScepticalDoctor Imagine if one were to cherrypick Daveys' study from the 1930s to claim that its odd that smoking appeared not to have a significant effect on lung cancer. That would obviously be a nonsensical argument given the results of other studies. https://t.co/PpS60aEB5T https://t.co/OhDLOpuLfh

Feb 26, 2022 · 14 likes · 2 shares · 1,067 followers View post →
Jesper Kiehn
@JesperKiehn · X

@KlausKblog den bedste tilgængelige evidens. https://t.co/NhcFmAQmqx https://t.co/ld7KrPSmLy https://t.co/yPwSnWalRx Og selvfølgelig også masser af dyreforsøg med kontrolgrupper, der underbygger den i forvejen meget stærke tilgængelige evidens om årsagssammenhæng. https://t.co/z8ymEaIYOS

Jan 1, 2022 · 11 followers View post →
Nick
@upRootNutrition · X

@thalesnemo @OlivePufa @LDLSkeptic @ethanjweiss @ZKForTre @deirdre_tobias @realDaveFeldman Those appear to be odds ratios from case-control studies, not relative risk ratios. In the aggregate, the relative risk of lung cancer from smoking is 5.5 in the prospective data. https://t.co/39eUjSllO7

Dec 25, 2021 · 9,516 followers View post →
P. Jeffrey Ungar, PhD
@pjungar · X

@The_Nutrivore @DiscoStew66 Apparently the "Systematic review with meta-analysis of the epidemiological evidence in the 1900s relating smoking to lung cancer" you favored didn't address the relevant question of what's happening *this* century.

May 28, 2021 · 1,836 followers View post →
Nick
@upRootNutrition · X

@pjungar @DiscoStew66 The aggregated relative risk of lung cancer from smoking is 5.5, brah. https://t.co/WyX9eoR0hr https://t.co/JWcZOulAtR

May 27, 2021 · 9,516 followers View post →
Bhopender Thakur
@TheBhupiThakur · X

RT @The_Nutrivore: @ketofan1000 https://t.co/39eUjS3Kpx

Apr 14, 2021 · 2 shares · 1,401 followers View post →
Bhopender Thakur
@TheBhupiThakur · X

RT @The_Nutrivore: @ketofan1000 https://t.co/39eUjS3Kpx

Dec 5, 2020 · 2 shares · 1,401 followers View post →
Klaus K
@KlausKblog · X

@PeterThinggaard @SaselineS @KVarming Lung cancer: https://t.co/ZUDM1MMlWv

Oct 28, 2020 · 1 like · 9,854 followers View post →
filippo masini
@filimasini · X

Systematic review with meta-analysis of the epidemiological evidence in the 1900s relating smoking to lung cancer ... https://t.co/TW2OKR1xjT

Dec 2, 2019 · 770 followers View post →
Medical Axioms
@medicalaxioms · X

@drdevireddy @Sixkadaanhigh @PNASNews Too many crayon colors. RR of 1-2 is often considered irrelevant. Anything with CI crossing 1 is irrelevant. I do love nuts. In contrast, smoking has RR for lung cancer of 4-100. https://t.co/BGpRkcAReK https://t.co/UhQYekvRez

Oct 31, 2019 · 65,125 followers View post →
filippo masini
@filimasini · X

Systematic review with meta-analysis of the epidemiological evidence in the 1900s relating smoking to lung cancer ... https://t.co/TW2OKR1xjT

Jun 4, 2019 · 770 followers View post →
Atomsk's Sanakan
@AtomsksSanakan · X

@gjbangar Re: "You wouldn’t be able to spread BS about mixing datasets if 2 sigma was acceptable"

Jan 16, 2019 · 3,360 followers View post →
Atomsk's Sanakan
@AtomsksSanakan · X

@gjbangar @kmpClimate @JaggerMickOZ @badmoonrising11 @StormSignalSA @PolAnimalAus @RoyPentland @Elizabe90736128 @jamieswilson @KCTaz @MLBinWA @EddyKurrents @miked194765 @priscian @seancunnion @HughAbercrombi3 @ag4slip @novakglobal @riktheozfrog @EngineerEarth @RegimeChangeBC @NotLineker @doctorjackpine @ejwwest @SylviaD32911201 @FraserMacLeod5 @craigthomler @Tokyo_Tom @ClimatismBlog @RJinBaltimore @JdavisWx @sueytonius @brandonrgates @JWSpry @Conserv00301750 @lyndoes @txtrue @munungus @caerbannog666 @maralago_ @msroberts0619 @PoeBrianL @flyonthewall182 @BradSchrag @Tangomitteckel @realiwasframed @JamesDe34061167 @Schmoop0521 @try2golf @Pandeism Re: "No one uses 2 sigma as a valid statistical result." You're either willfully ignorant or dishonest. Either way, it's quite telling that you resorted to such a blatantly false claim to justify your willful evasion of evidence. https://t.co/5Z

Jan 16, 2019 · 2 likes · 3,360 followers View post →