Trends Mol Med March 2013 PMID 23348042

Estrogen synthesis and signaling pathways during aging: from periphery to brain.

Jie Cui, Yong Shen, Rena Li

Mentions

10
Peak: 5 in Apr 2024
across 3 sources since Mar 2023

Extended reach

2,294
potential audience

Total likes

19

Video views

1,398

Mentions per month

Mar 2023 – Apr 2024

Where it's discussed

  • YouTube5 videos
  • News4 articles
  • X / Twitter1 posts

AI synopsis

What people are saying

The discussions emphasize the critical role of tissue-specific estrogen production, with participants referencing how the article addresses estrogen's influence on health issues like endometriosis and neurodegenerative diseases, using phrases such as 'truly understanding' to underscore the article's importance. The tone reflects a balanced appreciation of the research's relevance and a desire to deepen understanding, leading to moderate scores across all dimensions.

AgreementModerate agreement

Most discussions recognize the importance of localized estrogen production, reflecting a general consensus on the article's relevance.

InterestModerate interest

Participants show moderate curiosity, with mentions of how tissue-specific estrogen impacts health conditions like endometriosis and neurological health, indicating engagement with the topic.

EngagementModerate engagement

Comments include brief reflections and calls to understand estrogen pathways, but lack in-depth analysis or detailed debate.

ImpactModerate impact

The discussions suggest an awareness of the significance of estrogen signaling in aging and disease, hinting at a meaningful, though not transformative, influence on understanding these processes.

Abstract in brief

  • Estrogens are key female hormones involved in both reproductive and nonreproductive systems, produced not only in the ovaries but also in tissues like the liver, heart, muscle, bone, and brain, which leads to diverse functions.
  • The article discusses how estrogen synthesis, receptor distribution, and signaling pathways vary across different tissues, influencing their specific roles and impacts on health and disease.
  • Estrogens are linked to important functions and disorders such as cardiovascular health, osteoporosis, Alzheimer's disease, and Parkinson's disease, and understanding tissue-specific estrogen actions can help improve disease treatments.]

Top posts

Most liked on X and Bluesky
Diane
@Semiotics_Omnia · X

@Menstrual_H_P @BeYouPeriod @BattleWithEndo That means truly understanding why this local oestrogen production is critical. Cui J, Shen Y, Li R. Estrogen synthesis and signaling pathways during aging: from periphery to brain. https://t.co/V1TyZV1dcZ

Mar 25, 2023 · 2 likes · 897 followers View post →

All mentions

Understanding SERMs in Breast Cancer Hormone Therapy

This video explains breast cancer hormone therapy, covering receptor blockade, estrogen synthesis inhibition, and estrogen secretion suppression using SERMs like Tamoxifen, Raloxifene, aromatase inhibitors, and LHRH…

StudyMed · Apr 27, 2024 273 views
Diane
@Semiotics_Omnia · X

@Menstrual_H_P @BeYouPeriod @BattleWithEndo That means truly understanding why this local oestrogen production is critical. Cui J, Shen Y, Li R. Estrogen synthesis and signaling pathways during aging: from periphery to brain. https://t.co/V1TyZV1dcZ

Mar 25, 2023 · 2 likes · 897 followers View post →