PLoS One September 2013 PMID 23382817

Intermittent fasting dietary restriction regimen negatively influences reproduction in young rats: a study of hypothalamo-hypophysial-gonadal axis.

Sushil Kumar, Gurcharan Kaur

Download social card

Mentions

Peak: 1 in Oct 2019

across 5 sources since Oct 2019

Extended reach

74,945

potential audience

Total likes

1,101

Video views

49,689

Mentions per month

Oct 2019 – Nov 2022

Where it's discussed

News21 articles
X / Twitter4 posts
Facebook3 posts
Blogs3 articles
YouTube2 videos

AI synopsis

What people are saying

The discussions reflect curiosity about the biological mechanisms mentioned in the article, such as the effects on the hypothalamus and microbiome, with comments emphasizing the importance of caution given the limited research on humans. The tone varies from scientific curiosity to concern, with phrases like 'negative effects on reproductive abilities' and noting the need for further research, illustrating both interest and careful consideration of the study's implications.

AgreementModerate agreement

Most discussions acknowledge the study's findings that fasting can negatively impact reproductive health, especially in female rats, suggesting a general agreement with the publication's conclusions.

InterestHigh interest

The discussions show high interest due to mentions of new research topics like hypothalamus and microbiome effects, as well as concerns about human applications.

EngagementModerate engagement

Participants delve into specific biological mechanisms, such as hormonal disruptions and neuropeptide roles, indicating moderate to high engagement.

ImpactModerate impact

While some recognize potential implications for human health and fertility, there’s caution about current limitations, making the perceived impact moderate.

Abstract in brief

The study found that intermittent fasting dietary restriction (IFDR) negatively affects reproductive health in young rats by disrupting their hypothalamus-pituitary-gonadal (HPG) axis, leading to changes in body weight, blood glucose, hormonal levels, and estrous cycles.
It suggests that alterations in metabolic hormones like leptin, along with neuropeptides such as kisspeptin and NPY, play a key role in suppressing reproductive functions under IFDR by affecting neuronal structures and signaling in the hypothalamus.
These findings provide insight into how insufficient energy intake can impair fertility, highlighting potential cellular and molecular mechanisms underlying nutritional infertility, which may have implications for women experiencing conditions like anorexia nervosa.]

Read the full abstract

All mentions

Effects of Intermittent Fasting on Women's Hormonal Health and Reproduction

Intermittent Fasting affects women's hormones and reproductive health. Consult a healthcare provider before practicing IF, and ensure adequate calorie intake within your eating window. The study explores hormonal…

Holly Dolke · Oct 8, 2019 46,122 views

Fasted Training Benefits and Health Impacts Explained

Fasted training and calorie restriction are linked to health benefits like improved metabolism and increased lifespan. Fasting triggers cellular stress response, autophagy, and hormonal changes, contributing to its…

Raw Mad Strength · Dec 7, 2019 3,567 views

Jose Carreras

@JoseCar95237383 · X

@zafar_heer97 @AlejAvilaG https://t.co/UVZin93VFA There's a few, e.g. this one.

Nov 6, 2022 · 2 likes · 236 followers View post →

MotherOfCats

@MotherDeCats · X

@elepfff Aquí tienes la segunda: https://t.co/YCqIMQ4y9m

Sep 8, 2022 · 365 followers View post →

@Yozla_ · X

Mar 23, 2022 · 1 like · 5,180 followers View post →

Celestine

@CelestineBee · X

Dec 25, 2020 · 1 like · 19,475 followers View post →