It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermines the reliability of neuroscience" in @NatRevNeurosci. Today, we have the @CommonsSITC report on reproducibility. https://t.co/XVxC7WkJdq
Power failure: why small sample size undermines the reliability of neuroscience.
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Apr 2013 – Sep 2025Where it's discussed
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What people are saying
Overall, the discussions show strong consensus on the crucial message of the article, with posts emphasizing the need for larger sample sizes and better research practices. Words like 'must read,' 'important overview,' and 'game changer' convey a sense of urgency and influence, indicating high impact and engagement.
Most discussions highlight the importance and validity of the article, indicating strong agreement with its claims about the issues in neuroscience research.
Posts demonstrate high interest, frequently recommending the paper and discussing its concepts, such as statistical power and reproducibility.
Users actively engage by referencing related studies, sharing resources, and discussing methodological implications, showing deep involvement.
Many acknowledge the article's significance, emphasizing its role in shaping scientific practices and its relevance for improving research reliability.
Abstract in brief
- Low statistical power in neuroscience studies decreases the chances of identifying true effects and increases the likelihood that significant findings are false positives.
- The current research shows that most neuroscience studies have very low power, leading to overestimated effect sizes and results that are hard to replicate.
- Improving reproducibility in neuroscience requires following proven methodological principles to ensure more reliable and ethical research outcomes.]
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Most liked on X and Bluesky@heimbergecon Granted in my opinion statistical significance assuming nil hypothesis is a concept that should be retired as the gatekeeper of scientific significance, how meaningful are non significant results when you have this? https://t.co/0g33Bu7VXh
My Youtube-Series on Open Neuroscience & Psychology is now almost two years old. Thinking about doing a Marketing Version in the future.. @giladfeldman @AaronCharlton https://t.co/CKhZ5r5PjZ
For this semester's online teaching I created 3 videos on why, how and caveats of doing #openscience. https://t.co/z4aKGwGSt5 Grateful for all kinds of feedback
Methoden worden matig gedeeld. Data is moeilijk te verkrijgen ('it's my data'). De grootte van studies is te klein, waardoor effecten worden overschat en #wetenschap onethisch, niet-effectief en verspillend is. https://t.co/Iz0Z10LUcU 7/ https://t.co/2EWFURKsNx
@HenryYin19 I recommend this paper as a good overview of the issue: "Power failure: why small sample size undermines the reliability of neuroscience" by Button et al. (2013) https://t.co/UaC21KYXFf
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@FilipeGS97 @OssosPrateados @margaretmelonii @rafaelgloves A neurociência da inteligência ainda está no início. Replicação de estudos é baixa, poder estatístico é limitado e pouca pesquisa multivariada é feita https://t.co/tHr8LgYyi7
@heimbergecon Granted in my opinion statistical significance assuming nil hypothesis is a concept that should be retired as the gatekeeper of scientific significance, how meaningful are non significant results when you have this? https://t.co/0g33Bu7VXh
Surely you know that paper: Button, K. S., Ioannidis, J. P., Mokrysz, C., Nosek, B. A., Flint, J., Robinson, E. S., & Munafò, M. R. (2013). Power failure: why small sample size undermines the reliability of neuroscience. Nature reviews neuroscience, 14(5), 365-376.
Combined with publication bias, underpowered studies may lead to effect size inflation (Yarkoni and Braver https://t.co/acokP13FRe; Button et al. https://t.co/lIT9eetdbI). These arise because a small test sample requires a large effect to achieve significance.
Button et al. (2013) "Power failure: why small sample size undermines the reliability of neuroscience" Open Access: https://t.co/rRTJnex9KU  https://t.co/VX7zS3gKLn
RT @MHagenauer: @HenryYin19 I recommend this paper as a good overview of the issue: "Power failure: why small sample size undermines the r…
RT @MHagenauer: @HenryYin19 I recommend this paper as a good overview of the issue: "Power failure: why small sample size undermines the r…
@HenryYin19 I recommend this paper as a good overview of the issue: "Power failure: why small sample size undermines the reliability of neuroscience" by Button et al. (2013) https://t.co/UaC21KYXFf
RT @dmgroppe: Is there a good, recent update to this 2013 paper on how neuroscience studies are under-powered? https://t.co/o3ltpGjp4v
Is there a good, recent update to this 2013 paper on how neuroscience studies are under-powered? https://t.co/o3ltpGjp4v
Resultados similares han sido reportados para trabajos de evolución, psicología, neurociencias, epidemiología, biomedicina, economía, and so on. E.g. https://t.co/EcfwOUz58d https://t.co/F987ycBlMp https://t.co/V9oDJ2Xm8Q
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
RT @MarcusMunafo: It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermine…
It's ten years (!) since @ButtonKate and myself (w many others) published "Power Failure: why small sample size undermines the reliability of neuroscience" in @NatRevNeurosci. Today, we have the @CommonsSITC report on reproducibility. https://t.co/XVxC7WkJdq
@lakens @sauvikdasgupta And what do you think of this article? The authors write that sample size has an impact on type 1 error, too.. https://t.co/Apa8bUapXz
3⃣ Pienen tilastollisen voiman seuraukset: Power failure: why small sample size undermines the reliability of neuroscience https://t.co/DCjX25R68U Twiittiketju: https://t.co/SZE00pMU5D Tilastollinen voima tieteen toistettavuusongelman kannalta https://t.co/RXoKZKOO5B
@OSFramework @Bayer @Amgen Learn more about the importance of large sample sizes for statistical power and #research reliability. https://t.co/eryICb17L3 In relation to #neuroscience > https://t.co/vtApTZ6fUz
@Timothy0Leary Maybe this will help: Power failure: why small sample size undermines the reliability of neuroscience | Nature Reviews Neuroscience
RT @felixjannitsch: My Youtube-Series on Open Neuroscience & Psychology is now almost two years old. Thinking about doing a Marketing Versi…
My Youtube-Series on Open Neuroscience & Psychology is now almost two years old. Thinking about doing a Marketing Version in the future.. @giladfeldman @AaronCharlton https://t.co/CKhZ5r5PjZ
RT @NL_Wetenschap: Methoden worden matig gedeeld. Data is moeilijk te verkrijgen ('it's my data'). De grootte van studies is te klein, waar…
RT @NL_Wetenschap: Methoden worden matig gedeeld. Data is moeilijk te verkrijgen ('it's my data'). De grootte van studies is te klein, waar…
Methoden worden matig gedeeld. Data is moeilijk te verkrijgen ('it's my data'). De grootte van studies is te klein, waardoor effecten worden overschat en #wetenschap onethisch, niet-effectief en verspillend is. https://t.co/Iz0Z10LUcU 7/ https://t.co/2EWFURKsNx
@KordingLab "Why Most Published Research Findings Are False" and "Power failure: why small sample size undermines the reliability of neuroscience" should count as well
Power failure: why small sample size undermines the reliability of neuroscience - Nature Reviews Neuroscience, 8 years old https://t.co/eIMqnaxlTf
RT @T_Weissgerber: Data organization in spreadsheets: https://t.co/y6R9WEVUSJ Power failure: Why small sample size undermines the reliabil…
Data organization in spreadsheets: https://t.co/y6R9WEVUSJ Power failure: Why small sample size undermines the reliability of neuroscience: https://t.co/Da780krYps What exactly is ‘N’ in cell culture and animal experiments: https://t.co/m4M5bsEYVI
#IoannidisPowerFailure-1 [#Erkenntnistheorie:#Epistemology #ScientificMethod #Wahrheit:#Truth] "Nature Reviews Neuroscience 14(5), pp. 365–376 (2013) Power failure: why small sample size undermines the reliability of #neuroscience K. S. Button J. P. A. Ioannidis C. Mokrysz > https://t.co/uP6QMTnHmn
Power failure: why small sample size undermines the reliability of neuroscience https://t.co/yBFpio17AP
Power failure: why small sample size undermines the reliability of neuroscience | Nature Reviews Neuroscience https://t.co/X1Y7YYs6ge
Power failure: why small sample size undermines the reliability of neuroscience - https://t.co/VJMO8AFsYY
RT @felixjannitsch: For this semester's online teaching I created 3 videos on why, how and caveats of doing #openscience. https://t.co/z4…
For this semester's online teaching I created 3 videos on why, how and caveats of doing #openscience. https://t.co/z4aKGwGSt5 Grateful for all kinds of feedback
"Power failure: why small sample size undermines the reliability of neuroscience" https://t.co/uvY3PooyFc
REFERENCIA : Button KS, Ioannidis JP, Mokrysz C, Nosek BA, Flint J, Robinson ES, & Munafò MR (2013). Power failure: why small sample size undermines the reliability of neuroscience. Nature reviews. Neuroscience, 14 (5), 365-76 PMID: 23571845
Power failure: why small sample size undermines the reliability of neuroscience (Nat Rev Neuro, 2013) via /r/metaresearch https://t.co/cQRzkJM0p5
Power failure: why small sample size undermines the reliability of neuroscience https://t.co/4DHwpop7RP
Power failure: why small sample size undermines the reliability of neuroscience https://t.co/RHV0FpxDdH
Power failure: why small sample size undermines the reliability of neuroscience @doi:10.1038/nrn3475] bit.ly/15ebNAd
Must read! Power failure: why small sample size undermines the reliability of neuroscience http://www.nature.com/nrn/journal/vaop/ncurrent/full/nrn3475.html
"Power failure: why small sample size undermines the reliability of neuroscience" http://fb.me/LnpuyLIr
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