FEBS Lett July 2013 PMID 23735697

High glucose modulates IL-6 mediated immune homeostasis through impeding neutrophil extracellular trap formation.

Manjunath B Joshi, Apurva Lad, Alevoor S Bharath Prasad, Aswath Balakrishnan, Lingadakai Ramachandra, Kapaettu Satyamoorthy

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Peak: 26 in Apr 2020

across 3 sources since Dec 2016

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What people are saying

The discussions reflect a general interest in immune health, with many posts emphasizing practical ways to boost immunity, such as improving diet or lifestyle, rather than directly debating the study's scientific findings. The tone varies from informational to motivational, with some users sharing personal opinions or broader health advice, indicating engagement that extends past simple acknowledgment but stops short of deep scientific analysis.

AgreementNeither agree nor disagree

Most discussions acknowledge the study's findings but do not strongly endorse or oppose its conclusions.

InterestHigh interest

Many posts show high curiosity about immune health and microbiological research, indicating a strong interest in improving immune function.

EngagementModerate engagement

Several comments reference additional practices like diet, sun exposure, and exercise, demonstrating moderate engagement with the topic beyond surface-level comments.

ImpactModerate impact

The posts suggest the research has some influence in motivating health-related behaviors, but few discuss systemic or long-term implications.

Abstract in brief

Neutrophils are key players in innate immunity, producing neutrophil extracellular traps (NETs) to fight pathogens, but high blood sugar levels (hyperglycemia) can impair this function.
The study finds that IL6, a cytokine involved in immune responses, strongly promotes NET formation requiring energy, highlighting its role in immune regulation.
Chronic high glucose levels mimic a persistent inflammatory state in neutrophils, which reduces their ability to respond to infections, explaining why diabetics are more prone to infections.]

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Enhancing Immune Function in 3 Days Through Diet and Insights on High Blood Sugar Impact

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Veritas Vos Liberabit

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Government still just checking boxes and no mention of the responsibility of individuals to improve their own immune function by proper nutrition, spending time outdoors in the sun, and exercise. https://t.co/YzicnxU3Nu https://t.co/9xy7wejAd6

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@NightingaleKen · X

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Sep 6, 2020 · 4 shares · 645 followers View post →

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Linda

@ChefLippincott · X

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Sep 6, 2020 · 4 shares · 1,930 followers View post →

Al the wop

@Cat25Mom · X

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Ken D Berry MD

@KenDBerryMD · X

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Sep 6, 2020 · 13 likes · 4 shares · 301,020 followers View post →

Dunamis

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Patricia del Pino

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Barry Pearson

@BarryCPearson · X

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Al the wop

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Apr 16, 2020 · 33 likes · 10 shares · 301,020 followers View post →

Paul Joannides, PsyD

@PaulJoannides · X

@DrCastellanos @becomingaforce The word “diet” is not mentioned once in this study. https://t.co/dvfwvYU8aU Nor is it mentioned in this study: https://t.co/68M0HdY8R4 Nor is it mentioned even once in this study: https://t.co/AjN2UykSo5

Jul 25, 2019 · 694 followers View post →

MadeleineCastellanos

@DrCastellanos · X

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Tara Moriarty

@moriartylab.bsky.social · Bluesky

High glucose modulates IL-6 mediated immune homeostasis through impeding neutrophil extracellular trap formation http://onlinelibrary.wiley.com/doi/10.1016/j.febslet.2013.05.053/full

Dec 18, 2016 View post →

High glucose modulates IL-6 mediated immune homeostasis through impeding neutrophil extracellular trap formation.

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Abstract in brief

Top posts

All mentions

Enhancing Immune Function in 3 Days Through Diet and Insights on High Blood Sugar Impact

Impact of Orange Juice Sugar on Immune Function and High Glucose Effects