July 2013 PMID 23783199

Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective.

Dan W Grupe, Jack B Nitschke

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Mentions

276
Peak: 82 in May 2023
across 5 sources since Jan 2022

Extended reach

393,170
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AI synopsis

What people are saying

Many discussions reference key concepts from the article, such as the need to understand and manage uncertainty in anxiety. Phrases like 'take the first step' and 'minimize feelings of uncertainty' demonstrate a motivating tone that engages readers. The use of hashtags related to mental health and neuroscience contributes to the overall awareness and importance the community places on these topics.

AgreementModerate agreement

Most discussions show a general support for the importance of understanding anxiety and its neurobiological aspects.

InterestHigh interest

Posts indicate a high level of curiosity and relevance regarding the study and its findings.

EngagementModerate engagement

There are several thoughtful responses that analyze the implications of the research, suggesting deeper consideration of its methodology.

ImpactHigh impact

Participants express belief that the publication can significantly influence approaches to diagnosing and treating anxiety.

Abstract in brief

  • Uncertainty about future threats can lead to increased anxiety, affecting our ability to handle or mitigate these threats effectively.
  • The paper identifies five key neurobiological processes that help us respond adaptively to anticipated threats, highlighting their importance in managing anxiety.
  • By understanding how these processes can become dysfunctional in individuals with anxiety disorders, this research aims to improve approaches for diagnosing and treating clinical anxiety.

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CLaE
@leafs_s · X

Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective https://t.co/quRmuyCJLy

May 6, 2023 · 323 likes · 97 shares · 28,145 followers View post →
Hugo Chrost
@chrost_hugo · X

@DeFreitasGB @Nature https://t.co/3mUD7ra5JV

Nov 19, 2022 · 15 likes · 5 shares · 43,379 followers View post →
Leonhard Schilbach
@leoschilbach · X

Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective | Nature Reviews Neuroscience https://t.co/pFnonSQySA

Nov 6, 2023 · 8 likes · 6 shares · 6,743 followers View post →
Hugo Chrost
@chrost_hugo · X

@DrFernandoVF @Nature https://t.co/3mUD7ra5JV

Nov 19, 2022 · 5 likes · 43,379 followers View post →
ปราง Self-Growth
@Maprangself · X

ที่มา: Grupe, D. W., & Nitschke, J. B. (2013). "Uncertainty and anticipation in anxiety: An integrated neurobiological and psychological perspective." Nature Reviews Neuroscience.

Jan 20, 2025 · 5 likes · 8,156 followers View post →
ปราง Self-Growth
@Maprangself · X

ที่มา: Grupe, D. W., & Nitschke, J. B. (2013). "Uncertainty and anticipation in anxiety: An integrated neurobiological and psychological perspective." Nature Reviews Neuroscience.

Jan 21, 2025 · 4 likes · 8,156 followers View post →

All mentions

Anima.help
@Anima_help · X

Uncertainty doesn’t have to rule your life. Take the first step — complete the test at https://t.co/9uWHWsyj4o and get personalized guidance to support yourself. #mentalhealth #anxiety #neuroscience #Anima Source: https://t.co/uXlUWkXabC https://t.co/Ytu4Uc3Aqv

Aug 5, 2025 · 2 likes · 8 followers View post →
احمد الملحم
@a7md_ · X

يتفاعل الدماغ مع الخوف من حدث ما كما يتفاعل وقت حدوثه الفعلي. https://t.co/b0LXNncXmw https://t.co/stXQXxICPK

Feb 4, 2025 · 2 likes · 7,427 followers View post →
ปราง Self-Growth
@Maprangself · X

ที่มา: Grupe, D. W., & Nitschke, J. B. (2013). "Uncertainty and anticipation in anxiety: An integrated neurobiological and psychological perspective." Nature Reviews Neuroscience.

Jan 21, 2025 · 4 likes · 8,156 followers View post →
ปราง Self-Growth
@Maprangself · X

ที่มา: Grupe, D. W., & Nitschke, J. B. (2013). "Uncertainty and anticipation in anxiety: An integrated neurobiological and psychological perspective." Nature Reviews Neuroscience.

Jan 20, 2025 · 5 likes · 8,156 followers View post →
Rino LIX
@LixRino · X

RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

Apr 30, 2024 · 97 shares · 33 followers View post →
José Luis García-Hernández
@JosLuisGarHer · X

RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

Nov 20, 2023 · 97 shares · 223 followers View post →
Francisco J. Martínez | Psicólogo Biomédico
@Francisco_JMR9 · X

RT @leoschilbach: Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective | Nature Reviews Neu…

Nov 8, 2023 · 6 shares · 114 followers View post →
Vivek Misra
@iVivekMisra · X

RT @leoschilbach: Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective | Nature Reviews Neu…

Nov 7, 2023 · 6 shares · 2,966 followers View post →
Jess Ramos-Sanchez
@JessRamos93 · X

RT @leoschilbach: Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective | Nature Reviews Neu…

Nov 7, 2023 · 6 shares · 545 followers View post →
Sara Nicolau
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RT @leoschilbach: Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective | Nature Reviews Neu…

Nov 7, 2023 · 6 shares · 2,674 followers View post →
Clara H. Whyte
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RT @leoschilbach: Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective | Nature Reviews Neu…

Nov 7, 2023 · 6 shares · 935 followers View post →
Johanna Luise Mayer
@JohannaLuiseM · X

RT @leoschilbach: Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective | Nature Reviews Neu…

Nov 7, 2023 · 6 shares · 102 followers View post →
Leonhard Schilbach
@leoschilbach · X

Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective | Nature Reviews Neuroscience https://t.co/pFnonSQySA

Nov 6, 2023 · 8 likes · 6 shares · 6,743 followers View post →
leafs
@leafs_s_jp · X

Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective https://t.co/IOhGfCy9ev

Nov 5, 2023 · 4 likes · 203 followers View post →
José Luis García-Hernández
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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

Sep 16, 2023 · 97 shares · 223 followers View post →
Tintin Castro
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Jun 27, 2023 · 97 shares · 158 followers View post →
Mariana Fernández
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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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Amir Zuhdi
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Nazareth Castellanos
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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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Alexandra Davis
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Juan Daniel Gómez
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Guoda K
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Nature Mental Health
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Ritwik Niyogi
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Soiza-Reilly Lab
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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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Dr Valentina Mosienko (she/her)
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Jeong-Kyu Han
@jayhan97 · X

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dipanjanr
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May 8, 2023 · 97 shares · 899 followers View post →
CLaE
@leafs_s · X

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DJ Bolger
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최성규
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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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Mario Dulay, PhD
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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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Bryan Priego MD, PhD
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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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Professor Matthew C. Kiernan AM Nerve Centrals
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DiegoNeurociencias
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Li-Ming Hsu
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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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William Amaral
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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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Edwin Roberto Ramírez Benítez
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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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Taylor Guthrie
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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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Felipe Reis, PhD
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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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Agnes Ayton
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Kanat Chanthongdee
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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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Estefanía Conde-Blanco
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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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Clara H. Whyte
@ClaraHWhyte · X

RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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Dr Karolina Farrell
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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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Yoshie Udagawa 宇田川 淑恵
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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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Carlos Rebolleda
@RebolledaGil · X

RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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Mya
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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

May 7, 2023 · 97 shares · 568 followers View post →
Iván Padrón González
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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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Rodrigo Arzate-Mejía
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RT @leafs_s: Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspect…

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CLaE
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Nature Reviews Neuroscience Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective https://t.co/quRmuyCJLy

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PsiquiatriaIntegral
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Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective - Nature Reviews Neuroscience https://t.co/goqKIZjyKX https://t.co/cfl39ZaWXm

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Carlos Rebolleda
@RebolledaGil · X

@babidibuu Grupe, D. W., & Nitschke, J. B. (2013). Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective. Nature Reviews Neuroscience, 14(7), 488-501.

Apr 21, 2023 · 1 like · 7,754 followers View post →
Dyz̶er Nihil ψ
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RT @chrost_hugo: @______NickP @NatureNeuro You can access the study here: https://t.co/3mUD7raDzt

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Hugo Chrost
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@______NickP @NatureNeuro You can access the study here: https://t.co/3mUD7raDzt

Feb 18, 2023 · 3 likes · 1 share · 43,379 followers View post →
Josh Rodefer
@rodefer · X

@wooyoungahn @chrost_hugo @leoschilbach @NatureNeuro here it is Grupe, D., Nitschke, J. Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective. Nat Rev Neurosci 14, 488–501 (2013). https://t.co/qQ1nb6tE0F

Feb 18, 2023 · 2 likes · 447 followers View post →
john morley
@drjohnmorley · X

Grupe, D., Nitschke, J. Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective. Nat Rev Neurosci 14, 488–501 (2013). https://t.co/Z8dQhwD2SC

Jan 10, 2023 · 1 like · 8,319 followers View post →
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Shigekazu Ishihara
@shigekzishihara · X

RT @chrost_hugo: @DeFreitasGB @Nature https://t.co/3mUD7ra5JV

Nov 19, 2022 · 5 shares · 7,060 followers View post →
Hugo Chrost
@chrost_hugo · X

@DeFreitasGB @Nature https://t.co/3mUD7ra5JV

Nov 19, 2022 · 15 likes · 5 shares · 43,379 followers View post →
Hugo Chrost
@chrost_hugo · X

@DrFernandoVF @Nature https://t.co/3mUD7ra5JV

Nov 19, 2022 · 5 likes · 43,379 followers View post →
Abbasi 
@MohammedAbbasi · X

But if we can learn to minimise feelings of uncertainty, and push ourselves to encounter uncertain environments (https://t.co/p4H1At5mGD) more often, we can make ourselves better able to deal with them.

Jan 19, 2022 · 4,271 followers View post →