Haematologica July 2013 PMID 23813646

Recognizing nodal marginal zone lymphoma: recent advances and pitfalls. A systematic review.

Michiel van den Brand, J Han J M van Krieken

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Mentions

Peak: 3 in Feb 2022

across 3 sources since Jun 2020

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2,824

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435

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Jun 2020 – Feb 2022

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AI synopsis

What people are saying

The discussions highlight the importance of recent advances such as immunohistochemical markers and gene expression studies, with posts referencing specific cases, like Case 12, and questions about diagnostic challenges, which reflect a nuanced interest and recognition of the article's relevance in ongoing research and clinical practice.

AgreementModerate agreement

The discussions show a moderate level of support or acknowledgment of the importance of the article, recognizing advances in diagnosis, but also noting challenges remain.

InterestHigh interest

Participants seem highly interested, especially in the diagnostic complexities, as seen in references to case presentations and diagnostic techniques.

EngagementNeutral engagement

Posts are somewhat engaged, discussing specific cases and diagnostic details but lack deep analysis or broader implications.

ImpactModerate impact

The discussions suggest a recognition that the article influences diagnostic practices, but they do not express a sense of major paradigm shifts.

Abstract in brief

The diagnosis of nodal marginal zone lymphoma (NMZL) is challenging because there are no specific positive markers, making it often a diagnosis of exclusion and difficult to distinguish from other low-grade B-cell lymphomas.
Recent advances include the development of new immunohistochemical markers and gene expression studies that provide insights into its pathogenesis, particularly involving the nuclear factor kappa B pathway.
Despite these advances, NMZL remains poorly understood, but current data suggest it is a distinct entity separate from splenic, extranodal, and lymphoplasmacytic lymphomas, highlighting the need for further research for accurate diagnosis and targeted treatment.

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All mentions

Recognizing Nodal Marginal Zone Lymphoma: Advances and Challenges

Diagnosing nodal marginal zone lymphoma is complex due to a lack of specific markers. Recent developments include new immunohistochemical and gene expression techniques, but understanding remains limited. Further…

Pathologists Online · Jun 26, 2020 435 views

Image Pathology Robot

@ImageRoboPath · X

RT @PathologxOnline: Case 12. Alessandro Gambella MD (@AllyGambella), from @unito (Torino, Italy), presents a "double negative" diagnosis c…

Feb 20, 2022 · 2 shares · 844 followers View post →

Alessandro Gambella

@AllyGambella · X

RT @PathologxOnline: Case 12. Alessandro Gambella MD (@AllyGambella), from @unito (Torino, Italy), presents a "double negative" diagnosis c…

Feb 14, 2022 · 2 shares · 694 followers View post →

Pathologists Online

@PathologxOnline · X

Case 12. Alessandro Gambella MD (@AllyGambella), from @unito (Torino, Italy), presents a "double negative" diagnosis case. What is wrong with this 77 y ♂?

Feb 13, 2022 · 3 likes · 2 shares · 839 followers View post →