July 2013 PMID 23818100

Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol.

Ed Day, Peter W Bentham, Rhiannon Callaghan, Tarun Kuruvilla, Sanju George

Mentions

69
Peak: 6 in Dec 2025
across 5 sources since Mar 2017

Extended reach

15,133
potential audience

Total likes

21

Video views

690

Mentions per month

Mar 2017 – Jan 2026

Where it's discussed

  • Facebook50 posts
  • News12 articles
  • X / Twitter4 posts
  • YouTube2 videos
  • Blogs1 articles

AI synopsis

What people are saying

These discussions reflect a generally supportive stance towards the article, with many posts emphasizing the importance of appropriate thiamine dosing, such as the mention of 2250mg daily, and concerns about treatment protocols like refeeding syndrome, which indicates moderate but meaningful engagement on the clinical implications and need for further research.

AgreementModerate agreement

Most discussions acknowledge the importance of thiamine treatment for Wernicke-Korsakoff syndrome, showing general agreement with the article's emphasis on its clinical relevance.

InterestModerate interest

Posts express moderate interest by referencing dosage details and highlighting the ongoing uncertainty in optimal treatment, indicating engagement with the subject matter.

EngagementModerate engagement

Some comments delve into specifics such as dosing recommendations (e.g., 2250mg), refeeding concerns, and treatment protocols, reflecting a moderate level of detailed engagement.

ImpactModerate impact

Discussions highlight the significance of proper thiamine management for patient outcomes, suggesting these insights could influence clinical practices and future research directions.

Abstract in brief

  • Wernicke-Korsakoff Syndrome (WKS) is common among individuals who abuse alcohol, and thiamine has been used as the primary treatment for over 50 years, but optimal dosage and treatment duration are still unclear.
  • The review analyzed multiple databases, identified two relevant studies, and found limited data—only one study provided enough information for detailed analysis—highlighting the need for more research on effective thiamine dosing strategies.
  • The existing evidence suggests that different doses of intramuscular thiamine have varying effects, but definitive conclusions about the best dose, form, and treatment length require further studies.

Top posts

Most liked on X and Bluesky
バン@内科医のジレンマ
@lostphysicianYB · X

Wernicke脳症はコクランレビュー置いときます。 https://t.co/YXOqNVJxdB あんまり以降のエビデンス集積がない領域。 予防にしてもチアミン量いらないんじゃないかとか。糖との順番とかもね。 Refeeding症候群については、Antaa slideに詳しくまとめたので参照してください。 #セルトレスペース

Jul 19, 2023 · 3 likes · 4,469 followers View post →
Catherine Collins
@RD_Catherine · X

No dispute that B1 nec to treat Wernicke's encephalopathy in patients with alcoholism https://t.co/EII7PVcqY6 But 9 pairs of Pabrinex I+II recommended in BNF = 2250mg thiamine/d at higher dose

Jan 8, 2022 · 2 likes · 7,722 followers View post →
たけちゃん
@nitrotake · X

Thiamine for prevention and treatment of Wernicke‐Korsakoff Syndrome in people who abuse alcohol - Day, E - 2013 | Cochrane Library https://t.co/4vnZmYDT73

Feb 20, 2023 · 1,441 followers View post →
pharmacist
@pharmacistKAMO · X

Thiamine for prevention and treatment of Wernicke‐Korsakoff Syndrome in people who abuse alcohol - Day, E - 2013 | Cochrane Library https://t.co/kpPTd2mQb5

Jul 12, 2021 · 182 followers View post →

All mentions

バン@内科医のジレンマ
@lostphysicianYB · X

Wernicke脳症はコクランレビュー置いときます。 https://t.co/YXOqNVJxdB あんまり以降のエビデンス集積がない領域。 予防にしてもチアミン量いらないんじゃないかとか。糖との順番とかもね。 Refeeding症候群については、Antaa slideに詳しくまとめたので参照してください。 #セルトレスペース

Jul 19, 2023 · 3 likes · 4,469 followers View post →
たけちゃん
@nitrotake · X

Thiamine for prevention and treatment of Wernicke‐Korsakoff Syndrome in people who abuse alcohol - Day, E - 2013 | Cochrane Library https://t.co/4vnZmYDT73

Feb 20, 2023 · 1,441 followers View post →
Catherine Collins
@RD_Catherine · X

No dispute that B1 nec to treat Wernicke's encephalopathy in patients with alcoholism https://t.co/EII7PVcqY6 But 9 pairs of Pabrinex I+II recommended in BNF = 2250mg thiamine/d at higher dose

Jan 8, 2022 · 2 likes · 7,722 followers View post →
pharmacist
@pharmacistKAMO · X

Thiamine for prevention and treatment of Wernicke‐Korsakoff Syndrome in people who abuse alcohol - Day, E - 2013 | Cochrane Library https://t.co/kpPTd2mQb5

Jul 12, 2021 · 182 followers View post →
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No.: CD004033. DOI: 10.1002/14651858.CD004033.pub3. ผู้แต่ง. Day E; Bentham PW; Callaghan R; Kuruvilla T; George S. ตีพิมพ์เมื่อ. 1 กรกฎาคม 2013.

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