Thyroid January 2014 PMID 23902316

Moderate weight loss is sufficient to affect thyroid hormone homeostasis and inhibit its peripheral conversion.

Ritesh V Agnihothri, Amber B Courville, Joyce D Linderman, Sheila Smith, Robert Brychta, Alan Remaley, Kong Y Chen, Louis Simchowitz, Francesco S Celi

Mentions

15
Peak: 2 in May 2024
across 5 sources since Feb 2014

Extended reach

29,694
potential audience

Total likes

524

Video views

13,917

Mentions per month

Feb 2014 – Dec 2025

Where it's discussed

  • News7 articles
  • X / Twitter3 posts
  • YouTube2 videos
  • Reddit2 posts
  • Facebook1 posts

AI synopsis

What people are saying

The discussions reflect a moderate engagement with the article, citing specific findings like T3 decreases related to weight loss and its minimal impact on other hormones. Words like 'correlates,' 'inhibits,' and questions about TSH levels show analytical interest without extreme enthusiasm, indicating recognition of scientific significance but limited perception of immediate impact.

AgreementModerate agreement

Most discussions acknowledge and accept the findings that modest weight loss can influence thyroid hormone levels, as seen in comments supporting the research's conclusions.

InterestModerate interest

Participants show moderate interest as they reference specific details like T3 levels and nutritional status, but do not delve deeply into broader implications.

EngagementModerate engagement

Users engage with the content by referencing related questions, such as the effects of weight loss on TSH, indicating a moderate level of thoughtful discussion.

ImpactModerate impact

The discussions suggest the research could influence weight management and endocrinology, but the overall tone remains cautious rather than transformative.

Abstract in brief

  • Moderate weight loss can influence thyroid hormone balance, primarily by reducing the peripheral conversion of T4 to the active hormone T3, even without significant changes in TSH or free T4 levels.
  • In a 12-month study with overweight individuals, those who lost about 5-6 kg showed a significant decrease in T3 levels, which was closely linked to the amount of weight lost and their nutritional status.
  • The findings suggest that moderate dieting and weight loss mainly lead to a decrease in T3, reflecting an adaptation in thyroid hormone regulation related to changes in energy expenditure and nutritional state.

Top posts

Most liked on X and Bluesky
junglehoney
@KruseYouri · X

T3 concentration closely correlates with individual nutritional status, and moderate weight loss results in a decrease in T3 with minimal changes in other thyroid hormone homeostasis parameters." https://t.co/Gp2LuOFeAE

Dec 7, 2022 · 6 likes · 13,357 followers View post →
Mikki Williden PhD
@MikkiWilliden · X

Moderate Weight Loss Is Sufficient to Affect Thyroid Hormone Homeostasis and Inhibit Its Peripheral Conversion https://t.co/Cc3Q1g1s3S

Aug 7, 2024 · 2,233 followers View post →

All mentions

Mikki Williden PhD
@MikkiWilliden · X

Moderate Weight Loss Is Sufficient to Affect Thyroid Hormone Homeostasis and Inhibit Its Peripheral Conversion https://t.co/Cc3Q1g1s3S

Aug 7, 2024 · 2,233 followers View post →
junglehoney
@KruseYouri · X

T3 concentration closely correlates with individual nutritional status, and moderate weight loss results in a decrease in T3 with minimal changes in other thyroid hormone homeostasis parameters." https://t.co/Gp2LuOFeAE

Dec 7, 2022 · 6 likes · 13,357 followers View post →
Natural Healthy 365
@July03317075 · X

Moderate weight loss is sufficient to affect thyroid hormone homeostasis and inhibit its peripheral conversion – PubMed@|can weight loss lower tsh levels@|https://t.co/cw4GGtStZc https://t.co/gOWCtK5TbL

Sep 18, 2021 · 88 followers View post →
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