Physiol Behav August 2013 PMID 23911805

Biological mechanisms that promote weight regain following weight loss in obese humans.

Christopher N Ochner, Dulce M Barrios, Clement D Lee, F Xavier Pi-Sunyer

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Mentions

29
Peak: 17 in Aug 2025
across 5 sources since Aug 2020

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32,351,407
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Aug 2020 – Aug 2025

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AI synopsis

What people are saying

The discussions reflect a consensus on the significance of biological factors in weight regain, with phrases like 'good paper' and hypotheses about 'biological disposition' supporting the idea that the research could influence future interventions. The tone indicates respect for the findings, and the emphasis on biological mechanisms underscores the potential for impactful advancements in obesity management.

AgreementStrong agreement

Most discussions acknowledge the importance and validity of the research, indicating strong agreement with its focus on biological factors influencing weight regain.

InterestModerate interest

There is moderate interest, as the discussions highlight key concepts like biological predispositions but do not delve deeply into details or applications.

EngagementModerate engagement

The posts show some engagement by referencing specific aspects of the publication, such as the emphasis on biological mechanisms and implications for long-term weight management.

ImpactHigh impact

Participants recognize that this research could shape future approaches to obesity treatment, suggesting it has considerable impact in the field.

Abstract in brief

  • Weight loss dieting is the primary method for treating obesity, but long-term success rates for maintaining weight loss are low due to unclear reasons for weight regain.
  • Research indicates several biological factors (like fat cell behavior and metabolism) might lead to weight regain after dieting, suggesting these issues arise from the dieting process itself rather than just from losing weight.
  • To achieve lasting weight loss, interventions need to target and reduce these biological mechanisms that fight against weight loss rather than solely focusing on behavioral changes.

Top posts

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@barrydeutsch · X

Biological Mechanisms that Promote Weight Regain Following Weight Loss in Obese Humans https://t.co/lNcO7XhHlP https://t.co/Pur3PJ2XcP

Aug 18, 2020 · 5 likes · 2 shares · 7,887 followers View post →
Julianne Taylor, Nutritionist
@juliannejtaylor · X

Biological Mechanisms that Promote Weight Regain Following Weight Loss in Obese Humans - good paper https://t.co/oeoRu10XEj

Dec 28, 2020 · 2 likes · 5,315 followers View post →

All mentions

Jhe'stil
@jhestil · X

“It is hypothesized that these factors may combine to create a biological disposition that fosters the maintenance of high body weight and works to restore the highest body weight, thus precluding the long-term success of behavioral weight loss.” https://t.co/aAgOW0d8ft /10

Aug 22, 2022 · 1 like · 321 followers View post →
Julianne Taylor, Nutritionist
@juliannejtaylor · X

Biological Mechanisms that Promote Weight Regain Following Weight Loss in Obese Humans - good paper https://t.co/oeoRu10XEj

Dec 28, 2020 · 2 likes · 5,315 followers View post →
Find me at http://barrydeutsch.bsky.social
@barrydeutsch · X

Biological Mechanisms that Promote Weight Regain Following Weight Loss in Obese Humans https://t.co/lNcO7XhHlP https://t.co/Pur3PJ2XcP

Aug 18, 2020 · 5 likes · 2 shares · 7,887 followers View post →