June 1990 PMID 2395092

Relationship between contact time of applied dose and percutaneous absorption of minoxidil from a topical solution.

J J Ferry, J H Shepard, G J Szpunar

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Mentions

5
Peak: 1 in Mar 2023
across 3 sources since Mar 2023

Extended reach

117,274
potential audience

Total likes

2,412

Video views

116,112

Mentions per month

Mar 2023 – Oct 2025

Where it's discussed

  • YouTube2 videos
  • News2 articles
  • X / Twitter1 posts

AI synopsis

What people are saying

The social discussions highlight interest in how contact time affects absorption, with comments referencing the rapid absorption within the first hours and noting that the 1990 data may differ from newer formulations. The tone balances curiosity with cautious acknowledgment of the study's historical context, showing both respect for its findings and awareness of ongoing research.

AgreementModerate agreement

Most discussions acknowledge the findings, with some expressing agreement that absorption rates are rapid and implications for topical treatments are significant.

InterestHigh interest

Posts show high curiosity about the study, especially regarding how contact time influences drug absorption, reflecting strong engagement with the topic.

EngagementModerate engagement

Several posts reference specific aspects like absorption percentages and historical context, indicating a moderate depth of discussion.

ImpactModerate impact

The discussions suggest the research could influence future applications or formulations, though some see it as preliminary data from an older study.

Abstract in brief

  • The study involved 22 healthy men who applied minoxidil solution to their scalp and had varying contact times (1, 2, 4, and 115 hours) to see how much was absorbed.
  • Results showed that most of the drug was absorbed quickly, within the first few hours, with about 50% absorbed after 1 hour and over 75% after 4 hours, indicating rapid initial absorption.
  • The amount of minoxidil excreted in urine increased disproportionately with longer contact times, and the absorption process was nonlinear, while the body's elimination depended on a steady rate of diffusion from skin holding a reservoir of the drug.]

Top posts

Most liked on X and Bluesky
✨️Ultra-Woke Yaoi Mind Virus✨️
@Gender0ffender · X

@cisnistr Here's some more info about absorbtion rates, please note it's from 1990, so maybe new formulations absorb at different rates https://t.co/VRzo3ifA6R

Oct 27, 2025 · 4 likes · 1,162 followers View post →

All mentions

✨️Ultra-Woke Yaoi Mind Virus✨️
@Gender0ffender · X

@cisnistr Here's some more info about absorbtion rates, please note it's from 1990, so maybe new formulations absorb at different rates https://t.co/VRzo3ifA6R

Oct 27, 2025 · 4 likes · 1,162 followers View post →