Am J Physiol Endocrinol Metab February 2014 PMID 24326421

Musculoskeletal and prostate effects of combined testosterone and finasteride administration in older hypogonadal men: a randomized, controlled trial.

Stephen E Borst, Joshua F Yarrow, Christine F Conover, Unyime Nseyo, John R Meuleman, Judyta A Lipinska, Randy W Braith, Darren T Beck, Jeffrey S Martin, Matthew Morrow, Shirley Roessner, Luke A Beggs, Sean C McCoy, Darryl F Cannady, Jonathan J Shuster

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Mentions

Peak: 3 in May 2024

across 3 sources since Jan 2023

Extended reach

39,879

potential audience

Total likes

997

Video views

39,573

Mentions per month

Jan 2023 – Aug 2025

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AI synopsis

What people are saying

This post demonstrates mild agreement by referencing the study to address concerns about DHT's role in performance and hair loss, using casual language and personal opinions, which reflects a moderate level of interest and engagement, but does not delve into detailed scientific discussion or broader implications.

AgreementModerate agreement

The discussion references the study to support the idea that blocking DHT can prevent prostate enlargement without compromising athletic performance, showing moderate agreement with the article's findings.

InterestModerate interest

The post indicates some curiosity about the implications of DHT blocking, but mainly in the context of performance and hair loss rather than deep scientific engagement.

EngagementNeutral engagement

The comment is somewhat superficial, mainly sharing a personal interpretation and additional suggestions without detailed analysis.

ImpactNeutral impact

While it mentions the study's accessible nature and potential strategies like combining finasteride with dutasteride, it does not seem to influence broader clinical or scientific practices significantly.

Abstract in brief

The study investigated whether giving older men testosterone along with finasteride (which stops DHT production) could improve muscle strength and bone density without causing prostate enlargement.
Results showed that testosterone increased muscle strength, bone density, and reduced body fat, and these benefits were not affected by finasteride, which indicates DHT is not essential for these effects.
However, testosterone alone increased prostate size, but this enlargement was prevented when finasteride was given, suggesting DHT plays a key role in prostate growth but is not necessary for muscle or bone benefits.]

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