@MKTetra @Theholisticpsyc Although I agree, the current thinking in medicine is that there is a large genetic component - a "super sensitivity" to interpersonal dynamics: https://t.co/ukbPb52xDo
Genetics of borderline personality disorder: systematic review and proposal of an integrative model.
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May 2020 – Oct 2024Where it's discussed
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X / Twitter5 posts
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YouTube4 videos
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News3 articles
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What people are saying
Discussions demonstrate a strong curiosity about the genetic underpinnings of BPD, with comments emphasizing the 40% heritability and debates about the role of gene-environment interactions, showing that readers are critically engaging with the research and contemplating its broader implications.
Most discussions acknowledge the importance of genetics in BPD, citing the roughly 40% heritability and emphasizing biological factors as key contributors.
There is a high interest in the topic, with participants engaging in discussions about gene-environment interactions and the implications of the findings.
Posts are detailed, referencing specific aspects of the study like heritability estimates and the distinction between vulnerability and causal genes, indicating deep engagement.
While the conversations highlight the significance of genetic research in understanding BPD, some express cautious optimism rather than revolutionary change, suggesting moderate perceived impact.
Abstract in brief
- The systematic review highlights that borderline personality disorder (BPD) has a strong genetic component, with studies estimating about 40% of heritability, mainly supported by familial and twin research.
- Despite some evidence for gene-environment interactions, direct association studies have been limited and show no consistent links with common genes like the serotonin transporter, TPH1, or 5-HT1B receptor.
- The authors suggest shifting from focusing solely on vulnerability genes to considering plasticity genes, which influence how environmental factors affect the development of BPD, accounting for the high heritability but inconsistent genetic findings.]
Top posts
Most liked on X and BlueskyEsquizofrenia sendo hereditária: https://t.co/ioi7yesrhn. Borderline: https://t.co/TAYiTbZbd7 A lista continua, só TDI que é inconclusivo os estudos
@autisticdoc @CowsgomooGW2 @BlackshepSusan @emmarattenbury_ I did not say genes ‘cause’ abuse. The nature/nurture interaction is in relation to “nurture” (abuse) which is linked to higher likelihood of PTSD&BPD.Genetic influence is about incr RISK/vulnerability. Not CAUSAL. Risk v cause is v different Some papers https://t.co/STIREnXDzm
@AllenFrancesMD About 40% of BPD is due to heritability. This leaves about 60% as being due to environmental or other causes, but we cannot overlook biology as a primary factor. https://t.co/RRvoVbz7hD
All mentions
Understanding the Genetics and Complexity of Borderline Personality Disorder
Borderline personality disorder has a strong genetic component, with about 40% heritability. The research highlights the need to focus on plasticity genes, which influence how environment impacts the development of BPD…
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This educational video explores borderline personality disorder (BPD), highlighting its symptoms, individual experiences, and treatment options like therapy and medication. It emphasizes the importance of mental health…
Understanding Cluster B Personality Disorders and Genetic Factors
Explore the emotional and relational impacts of Emotional Intensity Disorder and Borderline Personality Disorder. This episode investigates clinical criteria, treatment options like DBT, and the strong genetic…
Understanding Borderline Personality Disorder and Its Genetic Foundations
Explore the emotional impact of Borderline Personality Disorder through personal stories, clinical insights, and treatment options like Dialectical Behavior Therapy, highlighting that it affects diverse populations and…
Esquizofrenia sendo hereditária: https://t.co/ioi7yesrhn. Borderline: https://t.co/TAYiTbZbd7 A lista continua, só TDI que é inconclusivo os estudos
@AllenFrancesMD About 40% of BPD is due to heritability. This leaves about 60% as being due to environmental or other causes, but we cannot overlook biology as a primary factor. https://t.co/RRvoVbz7hD
@vioverdu Sí, sí hay. https://t.co/JF4AApJCQu
@MKTetra @Theholisticpsyc Although I agree, the current thinking in medicine is that there is a large genetic component - a "super sensitivity" to interpersonal dynamics: https://t.co/ukbPb52xDo
@autisticdoc @CowsgomooGW2 @BlackshepSusan @emmarattenbury_ I did not say genes ‘cause’ abuse. The nature/nurture interaction is in relation to “nurture” (abuse) which is linked to higher likelihood of PTSD&BPD.Genetic influence is about incr RISK/vulnerability. Not CAUSAL. Risk v cause is v different Some papers https://t.co/STIREnXDzm