Br J Pharmacol June 2014 PMID 24467410

Cannabinoids inhibit cholinergic contraction in human airways through prejunctional CB1 receptors.

S Grassin-Delyle, E Naline, A Buenestado, C Faisy, J-C Alvarez, H Salvator, C Abrial, C Advenier, L Zemoura, P Devillier

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Mentions

53
Peak: 4 in May 2023
across 4 sources since Feb 2016

Extended reach

60,171
potential audience

Total likes

1,168

Video views

58,082

Mentions per month

Feb 2016 – Oct 2025

Where it's discussed

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AI synopsis

What people are saying

The discussions reflect a cautiously optimistic tone, citing the research's findings that cannabinoids, such as THC, act as bronchodilators via CB1 receptors, exemplified by phrases like 'may significantly impact asthma treatment' and 'could be a game-changer,' which demonstrate a recognition of the study's significance and relevance to healthcare and societal debates on medical cannabis.

AgreementModerate agreement

Most posts acknowledge the potential benefits of cannabinoids in treating asthma, with some highlighting specific research findings and clinical relevance.

InterestModerate interest

Discussions show moderate curiosity, especially around the therapeutic implications and societal perceptions of cannabis use for respiratory issues.

EngagementModerate engagement

Posts include references to scientific studies, personal opinions, and calls to consider the medical potential, indicating a fair level of thoughtful engagement.

ImpactModerate impact

The conversation suggests that the research could influence perspectives on cannabis as a viable treatment option, hinting at moderate-to-high potential impact.

Abstract in brief

  • This study found that certain cannabinoids, including THC and synthetic compounds like WIN552122 and CP55940, can reduce cholinergic contractions in human airways through activation of prejunctional CB1 receptors.
  • The effects were specific to CB1 receptors, as they were blocked by CB1 antagonists, while CB2-specific antagonists did not influence the response.
  • These findings suggest that activation of CB1 receptors inhibits airway contractions, which may explain the bronchodilation observed in marijuana smokers, providing insight into how cannabinoids could affect asthma and airway management.

Top posts

Most liked on X and Bluesky
C o l o r b l i n dㅤㅤㅤㅤㅤㅤㅤㅤㅤ
@ColorBlind0 · X

Cannabinoids inhibit cholinergic contraction in human airways through prejunctional CB1 receptors https://t.co/4ZHd77f8Bo Beneficial effects of cannabinoids (CB) in a murine model of allergen-induced airway inflammation: Role of CB1/CB2 receptors https://t.co/3GWIkGxS00

Feb 24, 2019 · 1 like · 471 followers View post →
Miguel Dias
@studios_believe · X

Can Cannabis Help Asthma - THC a Bronchodilator https://t.co/wR2Jx1TllA via @YouTube All Asthma suffers please must hear Dr. Thomas. It might safe your life.

May 26, 2023 · 1,207 followers View post →
SuckPoppit
@SuckPoppit · X

https://t.co/y2JTxe5yDZ https://t.co/h9bpCbk9Ze

Dec 21, 2024 · 169 followers View post →
VJRadRick
@VJRadRick · X

https://t.co/hpqqavhOya

Oct 4, 2025 · 111 followers View post →
VJRadRick
@VJRadRick · X

https://t.co/pthXDf3I7v

Oct 4, 2025 · 111 followers View post →
tad
@tetra9100 · X

Can Cannabis Help Asthma - THC a Bronchodilator https://t.co/aBelUMptGv @YouTubeより

May 13, 2023 · 8 followers View post →

All mentions

VJRadRick
@VJRadRick · X

https://t.co/hpqqavhOya

Oct 4, 2025 · 111 followers View post →
VJRadRick
@VJRadRick · X

https://t.co/pthXDf3I7v

Oct 4, 2025 · 111 followers View post →
SuckPoppit
@SuckPoppit · X

https://t.co/y2JTxe5yDZ https://t.co/h9bpCbk9Ze

Dec 21, 2024 · 169 followers View post →
Miguel Dias
@studios_believe · X

Can Cannabis Help Asthma - THC a Bronchodilator https://t.co/wR2Jx1TllA via @YouTube All Asthma suffers please must hear Dr. Thomas. It might safe your life.

May 26, 2023 · 1,207 followers View post →
Austin Reese
@r82471751 · X

@FBI @FBIWFO https://t.co/ZeW77kpPG3

May 20, 2023 · 6 followers View post →
Austin Reese
@r82471751 · X

https://t.co/ZeW77kpPG3

May 20, 2023 · 6 followers View post →
tad
@tetra9100 · X

Can Cannabis Help Asthma - THC a Bronchodilator https://t.co/aBelUMptGv @YouTubeより

May 13, 2023 · 8 followers View post →
Doctor Thomas
@MedicalDrThomas · X

Evidence-based research on Cannabis and Asthma. Bronchodilator? #cannabiseducation #cannabisnews #cannabisismedicine https://t.co/6aeE2CtdfZ

Mar 15, 2023 · 1 followers View post →
C o l o r b l i n dㅤㅤㅤㅤㅤㅤㅤㅤㅤ
@ColorBlind0 · X

Cannabinoids inhibit cholinergic contraction in human airways through prejunctional CB1 receptors https://t.co/4ZHd77f8Bo Beneficial effects of cannabinoids (CB) in a murine model of allergen-induced airway inflammation: Role of CB1/CB2 receptors https://t.co/3GWIkGxS00

Feb 24, 2019 · 1 like · 471 followers View post →