Editor’s top pick from the last decade of @stemcellreports: Breast cancer stem cells transition between epithelial and mesenchymal states reflective of their normal counterparts @ISSCR @martinperaJAX @WichaLab https://t.co/qpjdrt0Hsy https://t.co/vQj89w8uxl
Breast cancer stem cells transition between epithelial and mesenchymal states reflective of their normal counterparts.
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Dec 2022 – Nov 2023Where it's discussed
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What people are saying
The discussions reflect a balanced interest in the article's focus on cell state transitions, with phrases like 'important step forward' and 'potential for new therapies' suggesting recognition of its significance. The tone indicates genuine curiosity and acknowledgment of how understanding cellular plasticity could influence cancer treatment strategies.
Most discussions acknowledge the significance of the research findings, with some emphasizing the importance of cell plasticity in cancer progression.
People show moderate interest, noting the fascinating nature of cells transitioning states and the potential implications for treatment.
The conversations include references to the broader context of breast cancer research and cellular behavior, indicating a moderate depth of engagement.
Participants generally perceive the research as impactful, highlighting its relevance to understanding metastasis and resistance in breast cancer.
Abstract in brief
- Previous studies suggest breast cancer stem cells (BCSCs) are involved in metastasis, resistant to treatment, and contribute to cancer relapse.
- This research identifies two distinct states of BCSCs: mesenchymal-like (quiescent, found at the tumor's invasive edge) and epithelial-like (proliferative, located more centrally).
- Both BCSC types share similar gene-expression profiles across various breast cancer subtypes, indicating their plasticity enables them to switch states, which may aid in tissue invasion and spread of cancer.
Top posts
Most liked on X and BlueskyRT @CellPressNews: Editor’s top pick from the last decade of @stemcellreports: Breast cancer stem cells transition between epithelial and…
RT @CellPressNews: Editor’s top pick from the last decade of @stemcellreports: Breast cancer stem cells transition between epithelial and…
RT @CellPressNews: Editor’s top pick from the last decade of @stemcellreports: Breast cancer stem cells transition between epithelial and…
RT @CellPressNews: Editor’s top pick from the last decade of @stemcellreports: Breast cancer stem cells transition between epithelial and…
RT @CellPressNews: Editor’s top pick from the last decade of @stemcellreports: Breast cancer stem cells transition between epithelial and…
All mentions
Breast Cancer Stem Cells Transition between Epithelial and Mesenchymal States
Breast cancer stem cells are involved in metastasis, treatment resistance, and relapse. This study identifies two BCSC states—mesenchymal-like at the tumor edge and epithelial-like centrally—highlighting their…
Breast Cancer Stem Cells Transition Between Epithelial and Mesenchymal States
This study explores how breast cancer stem cells switch between epithelial and mesenchymal states, aiding in metastasis and treatment resistance. Understanding these transitions offers insights into cancer progression…
Breast Cancer Stem Cells Transition Between Epithelial and Mesenchymal States
Breast cancer stem cells transition between epithelial and mesenchymal states, reflecting their normal counterparts. This plasticity enables tissue invasion and cancer spread, contributing to metastasis, treatment…
Breast Cancer Stem Cells Transition Between Epithelial and Mesenchymal States
Breast cancer stem cells exhibit plasticity, switching between mesenchymal-like and epithelial-like states, which may facilitate tumor invasion, metastasis, and treatment resistance. This research highlights the…
Breast Cancer Stem Cell State Transition and Its Role in Metastasis
Breast cancer stem cells transition between epithelial and mesenchymal states, reflecting their normal counterparts, which influences metastasis and treatment resistance.
RT @CellPressNews: Editor’s top pick from the last decade of @stemcellreports: Breast cancer stem cells transition between epithelial and…
RT @CellPressNews: Editor’s top pick from the last decade of @stemcellreports: Breast cancer stem cells transition between epithelial and…
RT @CellPressNews: Editor’s top pick from the last decade of @stemcellreports: Breast cancer stem cells transition between epithelial and…
RT @CellPressNews: Editor’s top pick from the last decade of @stemcellreports: Breast cancer stem cells transition between epithelial and…
RT @CellPressNews: Editor’s top pick from the last decade of @stemcellreports: Breast cancer stem cells transition between epithelial and…
Editor’s top pick from the last decade of @stemcellreports: Breast cancer stem cells transition between epithelial and mesenchymal states reflective of their normal counterparts @ISSCR @martinperaJAX @WichaLab https://t.co/qpjdrt0Hsy https://t.co/vQj89w8uxl