February 2014 PMID 24519767

Contralateral mastectomy and survival after breast cancer in carriers of BRCA1 and BRCA2 mutations: retrospective analysis.

Kelly Metcalfe, Shelley Gershman, Parviz Ghadirian, Henry T Lynch, Carrie Snyder, Nadine Tung, Charmaine Kim-Sing, Andrea Eisen, William D Foulkes, Barry Rosen, Ping Sun, Steven A Narod

Mentions

41
Peak: 1 in Feb 2014
across 5 sources since Feb 2014

Extended reach

4,867
potential audience

Total likes

12

Video views

4,623

Mentions per month

Feb 2014 – Oct 2025

Where it's discussed

  • News34 articles
  • YouTube2 videos
  • Facebook2 posts
  • Blogs2 articles
  • X / Twitter1 posts

AI synopsis

What people are saying

The posts show a cautious yet interested tone, with mentions like 'Intriguing data' and the anticipation of seeing whether long-term outcomes align with prior studies, such as Kelly Metcalfe et al. (2014). The tone suggests curiosity and recognition of the study's potential influence without strong emotional or definitive language.

AgreementModerate agreement

There is a tentative agreement, with users expressing interest in long-term outcomes but also acknowledging the need for further evidence, indicating a moderate level of support.

InterestModerate interest

Discussions show genuine curiosity about the study's long-term results and implications, suggesting moderate to high interest.

EngagementModerate engagement

Posts include references to related research and future outcomes, reflecting a thoughtful and engaged approach, though not deeply technical.

ImpactModerate impact

Comments highlight the potential significance of the findings for patient decision-making and future research, signaling a modest impact.

Abstract in brief

  • The study aimed to compare survival rates between women with BRCA-related breast cancer who underwent either a bilateral mastectomy or a unilateral mastectomy.
  • Out of 390 women followed for up to 20 years, those who had a contralateral mastectomy had a significantly higher 20-year survival rate (88%) compared to those who had only unilateral mastectomy (66%).
  • While the initial analysis showed a 48% reduction in breast cancer death risk linked to contralateral mastectomy, further adjusted analysis did not find this association significant, suggesting that more research is needed.

Top posts

Most liked on X and Bluesky
Toronto Breast Surgery Collaborative
@TOBreastCO · X

@adwilliams5 @spshubeck @MPilewskie @MSKCancerCenter @AnnSurgOncol Intriguing data! It will be interesting to see if outcomes at 20 years will be similiar to those reported by Kelly Metcalfe et al. BMJ 2014: 348. https://t.co/Cv2pDGgUJM

May 25, 2022 · 2 likes · 245 followers View post →

All mentions

Toronto Breast Surgery Collaborative
@TOBreastCO · X

@adwilliams5 @spshubeck @MPilewskie @MSKCancerCenter @AnnSurgOncol Intriguing data! It will be interesting to see if outcomes at 20 years will be similiar to those reported by Kelly Metcalfe et al. BMJ 2014: 348. https://t.co/Cv2pDGgUJM

May 25, 2022 · 2 likes · 245 followers View post →