Arterioscler Thromb Vasc Biol March 2014 PMID 24554606

Smoking and cardiovascular disease: mechanisms of endothelial dysfunction and early atherogenesis.

Barbara Messner, David Bernhard

Mentions

32
Peak: 5 in Dec 2023
across 3 sources since Jul 2019

Extended reach

167,023
potential audience

Total likes

164

Video views

3,461

Mentions per month

Jul 2019 – Oct 2025

Where it's discussed

  • X / Twitter16 posts
  • News14 articles
  • YouTube2 videos

AI synopsis

What people are saying

Discussions reflect strong agreement and high interest, with users mentioning specific mechanisms such as decreased nitric oxide and increased thrombogenic processes, illustrating their deep engagement. The tone and choice of words, like 'most harmful' or 'key risk factor,' emphasize the perceived importance and potential impact of the research findings on public health awareness.

AgreementStrong agreement

Most discussions strongly align with the article’s message, emphasizing the harmful effects of smoking on endothelial function and cardiovascular risk, with statements like 'smoking reduces NO' and 'smoking is the most influential risk factor.'

InterestHigh interest

The discussions show high interest, with users exploring mechanisms, sharing related scientific insights, and referencing scientific studies, indicating curiosity about detailed processes.

EngagementHigh engagement

Comments include scientific explanations, references to research, and calls to consider implications, demonstrating deep engagement and active participation.

ImpactHigh impact

The conversations highlight the significant influence of the publication, as many recognize smoking as a crucial modifiable factor in cardiovascular health and discuss strategies and scientific evidence supporting this impact.

Abstract in brief

  • Smoking is a major preventable risk factor for atherosclerosis, primarily affecting the endothelium (inner lining of blood vessels) by reducing nitric oxide and increasing adhesion molecules, leading to vascular dysfunction.
  • Smoking promotes a pro-inflammatory and pro-thrombotic environment through increased platelet and macrophage adherence, oxidative modification of lipoproteins, and formation of foam cells, all contributing to early atherogenesis.
  • While there are gaps in understanding the full impact of smoking on cardiovascular health, quitting smoking is the most effective way to reverse existing damage and lower the risk of serious heart-related diseases.]

Top posts

Most liked on X and Bluesky
Dr. Deniz GÖKSEDEF
@dgoksedef · X

(7) Sigara damarın iç tabakasını en fazla olumsuz etkileyen risk faktörüdür. Bir diğer özelliği de VAZGEÇİLEBİLİR olmasıdır. Buna ait klasik kabul edilebilecek bilimsel makaleyi de buraya bırakayım. https://t.co/0E3UOvhzNY

Apr 26, 2020 · 15 likes · 4 shares · 17,722 followers View post →
Tigress
@tigresseleanor · X

You must all smoke to gain immunity to smoking ? "In response to smoke exposure, endothelial cells are known to release inflammatory and proatherogenic cytokines. All these processes lead to endothelial dysfunction." https://t.co/0wIv0TUrjO.

Dec 26, 2023 · 5 likes · 1 share · 6,089 followers View post →
Clint O'Meley
@Clint_OMeley · X

@PeterJAnderson_ @KetoCyclist @dan_soffer @JohnKastelein @WillBrink @pabeda1 @drpablocorral @lipo_fan @Drlipid @alavallecobo @BNordestgaard @realDaveFeldman A good review on AHA re smoking and ASCVD: https://t.co/wtRagroGz2

Jun 18, 2023 · 2 likes · 103 followers View post →
lisa grant
@lisagra74368244 · X

Smoking and Cardiovascular Disease | Arteriosclerosis, Thrombosis, and Vascular Biology https://t.co/VAu8mUjsbK

Jul 25, 2019 · 2 likes · 4 followers View post →
Sama Hoole
@SamaHoole · X

@JimmySm58405905 @rorntv Hell of a day! I want to get off this wild ride. https://t.co/XH6mIJERo0

Oct 5, 2022 · 1 like · 47,081 followers View post →
Melaleuca #NoWar #NoNukes #NoHate StopExploitation
@mama_melaleuca · X

タバコに対する免疫を獲得するために 皆,喫煙しなければならないのか? タバコの煙への曝露に応答して 内皮細胞は炎症誘発性サイトカインや 動脈硬化を促進するサイトカインを放つことが知られている これら全ての過程が内皮機能障害を引起こす https://t.co/Lz6lX0NEnV 2/ https://t.co/aziJzE1LN9

Dec 29, 2023 · 1 like · 1 share · 1,588 followers View post →

All mentions

SION|産業保健理学療法士
@sion_sangyo_ · X

喫煙→内皮機能破壊 高血圧→血管への機械的ストレス 高コレステロール→炎症反応亢進 これらが「内皮機能不全」という共通経路で相乗効果を発揮。単純な足し算ではなく、指数関数的にリスクが急上昇! 科学的根拠に基づく予防が重要です。 https://t.co/9dqVYykERD #血管内皮 #動脈硬化 #理学療法

Jul 29, 2025 · 11 followers View post →
Melaleuca #NoWar #NoNukes #NoHate StopExploitation
@mama_melaleuca · X

RT @mama_melaleuca: タバコに対する免疫を獲得するために 皆,喫煙しなければならないのか? タバコの煙への曝露に応答して 内皮細胞は炎症誘発性サイトカインや 動脈硬化を促進するサイトカインを放つことが知られている これら全ての過程が内皮機能障害を引起こす h…

Mar 19, 2024 · 1 share · 1,588 followers View post →
Melaleuca #NoWar #NoNukes #NoHate StopExploitation
@mama_melaleuca · X

タバコに対する免疫を獲得するために 皆,喫煙しなければならないのか? タバコの煙への曝露に応答して 内皮細胞は炎症誘発性サイトカインや 動脈硬化を促進するサイトカインを放つことが知られている これら全ての過程が内皮機能障害を引起こす https://t.co/Lz6lX0NEnV 2/ https://t.co/aziJzE1LN9

Dec 29, 2023 · 1 like · 1 share · 1,588 followers View post →
ず
@zu2 · X

RT @tigresseleanor: You must all smoke to gain immunity to smoking ? "In response to smoke exposure, endothelial cells are known to release…

Dec 27, 2023 · 1 share · 3,230 followers View post →
Tigress
@tigresseleanor · X

You must all smoke to gain immunity to smoking ? "In response to smoke exposure, endothelial cells are known to release inflammatory and proatherogenic cytokines. All these processes lead to endothelial dysfunction." https://t.co/0wIv0TUrjO.

Dec 26, 2023 · 5 likes · 1 share · 6,089 followers View post →
Architect Neo
@Neo1Architect · X

▶️Το κάπνισμα μειώνει δραματικά το μονοξείδιο του αζώτου (ΝΟ) που παράγει ο οργανισμός μας. Ένα τσιγάρο πυροδοτεί άμεσα τουλάχιστον δύο θρομβογόνες διεργασίες για παράδειγμα. ΚΟΨΤΕ ΤΟ ΤΣΙΓΑΡΟ για το καλό της καρδιάς σας, των αγγείων σας ευρύτερα.. https://t.co/SxcWT0yMto

Dec 26, 2023 · 616 followers View post →
Architect Neo
@Neo1Architect · X

@KetoPhilosophy @CentroPrawo @robertlufkinmd Smoking reduces NO. One cigarette instantly triggers at least two thrombogenic processes as an example: https://t.co/SxcWT0yMto

Dec 26, 2023 · 1 like · 616 followers View post →
Clint O'Meley
@Clint_OMeley · X

@PeterJAnderson_ @KetoCyclist @dan_soffer @JohnKastelein @WillBrink @pabeda1 @drpablocorral @lipo_fan @Drlipid @alavallecobo @BNordestgaard @realDaveFeldman A good review on AHA re smoking and ASCVD: https://t.co/wtRagroGz2

Jun 18, 2023 · 2 likes · 103 followers View post →
The Ancestral Doc
@j_t_2390 · X

@JohnnyScott234 @MasalaFry69 @kevtharris @FusionProgGuy @ElieJarrougeMD @Dr__Guess @NutritionMadeS3 https://t.co/AdnEDFdAGJ

Mar 16, 2023 · 208 followers View post →
Sama Hoole
@SamaHoole · X

@JimmySm58405905 @rorntv Hell of a day! I want to get off this wild ride. https://t.co/XH6mIJERo0

Oct 5, 2022 · 1 like · 47,081 followers View post →
ramazan çağlar
@bayrota · X

RT @DenizGoksedef: (7) Sigara damarın iç tabakasını en fazla olumsuz etkileyen risk faktörüdür. Bir diğer özelliği de VAZGEÇİLEBİLİR olmas…

Apr 27, 2020 · 4 shares · 19 followers View post →
Risus Tamara
@RisusT · X

RT @DenizGoksedef: (7) Sigara damarın iç tabakasını en fazla olumsuz etkileyen risk faktörüdür. Bir diğer özelliği de VAZGEÇİLEBİLİR olmas…

Apr 26, 2020 · 4 shares · 298 followers View post →
Prof Dr. Nebahat BULUT
@BulutGulcuN · X

RT @DenizGoksedef: (7) Sigara damarın iç tabakasını en fazla olumsuz etkileyen risk faktörüdür. Bir diğer özelliği de VAZGEÇİLEBİLİR olmas…

Apr 26, 2020 · 4 shares · 84,305 followers View post →
Dr. Deniz GÖKSEDEF
@dgoksedef · X

(7) Sigara damarın iç tabakasını en fazla olumsuz etkileyen risk faktörüdür. Bir diğer özelliği de VAZGEÇİLEBİLİR olmasıdır. Buna ait klasik kabul edilebilecek bilimsel makaleyi de buraya bırakayım. https://t.co/0E3UOvhzNY

Apr 26, 2020 · 15 likes · 4 shares · 17,722 followers View post →
Not Very Good
@notverygoodnow · X

@slithrael @VeganLinked @drjkahn @SBakerMD https://t.co/lkRZdMWYtT

Feb 21, 2020 · 45 followers View post →
lisa grant
@lisagra74368244 · X

Smoking and Cardiovascular Disease | Arteriosclerosis, Thrombosis, and Vascular Biology https://t.co/VAu8mUjsbK

Jul 25, 2019 · 2 likes · 4 followers View post →