February 2015 PMID 24603693

Metabolic signature of sun exposed skin suggests catabolic pathway overweighs anabolic pathway.

Manpreet Randhawa, Vineet Sangar, Samantha Tucker-Samaras, Michael Southall

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Mentions

3
Peak: 1 in Jul 2019
across 2 sources since Jul 2019

Extended reach

6,069
potential audience

Total likes

30

Video views

531

Mentions per month

Jul 2019 – Nov 2023

Where it's discussed

  • X / Twitter2 posts
  • YouTube1 videos

AI synopsis

What people are saying

The discussions highlight the metabolic processes involved in sun-induced skin damage, mentioning 'oxidative state' and 'metabolomic signature,' which demonstrates engagement with the scientific content. The tone emphasizes the importance of understanding how UV exposure affects skin biology, reflecting curiosity and concern about skin health and aging.

AgreementModerate agreement

The posts express agreement with the idea that UV exposure causes skin damage through oxidative and metabolic pathways, supporting the study's findings.

InterestHigh interest

The discussions show high interest, focusing on the mechanisms behind sun damage and photoaging, which are relevant to skin health and aging research.

EngagementModerate engagement

Comments engage with scientific concepts like 'metabolomic signature,' indicating a moderate level of participation and understanding.

ImpactModerate impact

The emphasis on skin damage and photoaging suggests these discussions could influence public awareness or future research directions.

Abstract in brief

  • Sun-exposed skin shows phenotypic changes due to photoaging, with metabolomic data indicating increased oxidative stress and a preference for catabolic over anabolic processes.
  • The study analyzed metabolites from sun-exposed and protected skin in 25 people, revealing that sun exposure promotes pathways that break down molecules (catabolism) and generate reactive oxygen species.
  • These molecular changes suggest that sun-exposed skin experiences a cycle where oxidative stress and catabolic pathways reinforce each other, impacting skin biology and aging.]

Top posts

Most liked on X and Bluesky
Metabolon, Inc.
@Metabolon · X

Why does UV exposure lead to sun-damaged skin? Read more on the metabolomic signature of sun-exposed skin contributing to a more oxidative state in the skin resulting in photoaging: https://t.co/xQJbeD4Uz0 #metabolomics #skin #research #uvsafetymonth

Jul 8, 2020 · 3 likes · 1 share · 2,768 followers View post →
Metabolon, Inc.
@Metabolon · X

UV exposure leads to sun-damaged skin -- but why? Read more on the metabolomic signature of sun-exposed skin contributing to a more oxidative state in the skin that results in photoaging: https://t.co/dcDML3RP1i #metabolomics #skin #research #uvsafetymonth https://t.co/pmUguWo8FK

Jul 1, 2019 · 2 likes · 2,768 followers View post →

All mentions

Metabolon, Inc.
@Metabolon · X

Why does UV exposure lead to sun-damaged skin? Read more on the metabolomic signature of sun-exposed skin contributing to a more oxidative state in the skin resulting in photoaging: https://t.co/xQJbeD4Uz0 #metabolomics #skin #research #uvsafetymonth

Jul 8, 2020 · 3 likes · 1 share · 2,768 followers View post →
Metabolon, Inc.
@Metabolon · X

UV exposure leads to sun-damaged skin -- but why? Read more on the metabolomic signature of sun-exposed skin contributing to a more oxidative state in the skin that results in photoaging: https://t.co/dcDML3RP1i #metabolomics #skin #research #uvsafetymonth https://t.co/pmUguWo8FK

Jul 1, 2019 · 2 likes · 2,768 followers View post →