PubHawk
October 2014 PMID 24615175

Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer.

A M Poff, C Ari, P Arnold, T N Seyfried, D P D'Agostino

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Mentions

70
Peak: 12 in Sep 2020
across 6 sources since Apr 2016

Extended reach

164,352
potential audience

Total likes

245

Video views

5,157

Mentions per month

Apr 2016 – Jul 2025

Where it's discussed

  • Facebook33 posts
  • X / Twitter25 posts
  • YouTube4 videos
  • News3 articles
  • Blogs3 articles
  • Reddit2 posts

AI synopsis

What people are saying

The collective discussions express strong agreement with the study, with many posters emphasizing the potential therapeutic benefits of ketone supplementation and ketogenic diets, describing ketones as 'natural chemotherapy' and referencing their ability to inhibit cancer growth. The tone ranges from enthusiastic to cautiously optimistic, reflecting both scientific interest and debate about clinical applications.

AgreementModerate agreement

Most discussions show strong support for the article's findings, with many posts emphasizing the potential of ketone therapy as a cancer treatment.

InterestHigh interest

The topic clearly captures high interest, evidenced by the use of enthusiastic language and references to exciting potential medical developments.

EngagementHigh engagement

Participants often reference specific mechanisms, like ketones acting as natural chemotherapy and the benefits of ketogenic diets, indicating deep engagement.

ImpactModerate impact

While some post highlight significant implications, the overall excitement and potential for new treatments suggest a moderate impact, though some skepticism remains.

Abstract in brief

  • Ketone supplementation reduces tumor cell growth and increases survival in mice with metastatic cancer, functioning independently of glucose levels or calorie restriction.
  • In vitro studies show that ketones decrease the proliferation and viability of metastatic cancer cells, even in high glucose conditions.
  • The research suggests that using ketone precursors as a potential cancer therapy warrants further investigation for future clinical application.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Nick Norwitz MD PhD
@nicknorwitz · X

Cancer & #Keto

Sep 19, 2020 · 37 likes · 9 shares · 109,680 followers View post →
KetoScience
@KetoScience · X

Ketone administration elicited anticancer effects in vitro and in vivo independent of glucose levels or calorie restriction. #cancer #keto #science https://t.co/3t1DeHiLnZ

May 28, 2019 · 6 likes · 1 share · 668 followers View post →
Dr. Websternator
@Chris_Lavina · X

@GarrettIsVibin Like I said, works on a lot not all. But considering we can create organs factories with perfectly matching DNA if not for bs "ethics" yeah my statement stands. https://t.co/9cwW8CLWWE https://t.co/b5TLamjxas https://t.co/pvA1dZffH0 https://t.co/Bd3kIGg1C2

Aug 2, 2020 · 4 likes · 495 followers View post →
MorozkoForge
@MorozkoForge · X

@jurodivi @sgcarney @seagertp @Iceman_Hof @bengreenfield @GritCoachMd @dietsloseweight @UpTalkPodcast Ketones are natural chemotherapy -- e.g., metastatic cancers inhibited. https://t.co/sMy5ueuNGN Deliberate cold exposure clears glucose from blood, starving cancer cells, and shifts metabolism to ketone production, killing tumors. Cold = double whammy for cancer.

Jan 29, 2020 · 3 likes · 2,360 followers View post →
MorozkoForge
@MorozkoForge · X

@Mangan150 Moreover, the ketones produced by his brown fat metabolism are toxic to metastasizing cancer cells. https://t.co/sMy5uedcPf Ketones are your body's natural chemotherapy, so activation of brown fat both starves cancer cells AND poisons them. @Mangan150

Dec 20, 2019 · 3 likes · 1 share · 2,360 followers View post →
KetoScience
@KetoScience · X

Ketone administration elicited anticancer effects in vitro and in vivo independent of glucose levels or calorie restriction. #cancer #keto #science https://t.co/3t1DeHiLnZ

Feb 28, 2019 · 2 likes · 1 share · 668 followers View post →

All mentions

CapiTwan
@CousinTonyIII · X

@ProfDuckDuckGo @DocDeezWhat @anthony_chaffee @SBakerMD @DrRobKiltz Source: Poff, A. M., et al. (2014). “Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer.” International Journal of Cancer, 135(7), 1711–1720. Source: Weber, D. D., et al. (2021). “Ketogenic diet in the treatment of cancer –

Jul 22, 2025 · 900 followers View post →
tune
@keisuke4713 · X

高圧酸素療法(HBOT) 低酸素は悪性腫瘍の重要な特徴,細胞生存,血管新生,解糖,glutamin分解代謝,転移⬆️関係 単独でも併用でも強力な抗腫瘍活性 特ケトン代謝療法(KMT)と組み合わせた場合に腫瘍⬇️ https://t.co/H9NJgfRaCX KE

Jan 15, 2025 · 3,734 followers View post →
thalesnemo
@thalesnemo · X

@DavidInFlalala @SamaHoole @BillAckman MORE BULL SHIT — VEGAN ! OMG you are SO BRAIN DAMAGED— AND UTTERLY FACTUALLY WRONG — as to be COMICAL! Dr Potato Head died as a NUTTER ! Dr Twiggy is a NUTTER https://t.co/We1tgTTxFP https://t.co/m8Q0RNJAcb https://t.co/Rhnf5HeLMf https://t.co/hsXWB34CPo https://t.co/lkNvr2Sd5B

Nov 28, 2024 · 1,110 followers View post →
健康ノート
@JuStADOcToR_Jp · X

Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer https://t.co/BsefeWv9Os

May 11, 2022 · 110 followers View post →
Shared Nutrition ❣️
@sharednutrition · X

RT @nicknorwitz: Cancer & #Keto

Sep 20, 2020 · 9 shares · 102 followers View post →
Tim Overlin
@TimOverlin · X

RT @nicknorwitz: Cancer & #Keto

Sep 19, 2020 · 9 shares · 750 followers View post →
Dawn K.
@dawn_kalsbeek · X

RT @nicknorwitz: Cancer & #Keto

Sep 19, 2020 · 9 shares · 633 followers View post →
ely martinez
@nelke47 · X

RT @nicknorwitz: Cancer & #Keto

Sep 19, 2020 · 9 shares · 513 followers View post →
CarnivoreKeto
@CarnivoreKeto · X

RT @nicknorwitz: Cancer & #Keto

Sep 19, 2020 · 9 shares · 18,661 followers View post →
Alexander
@Alexand09896703 · X

癌症与#Keto

Sep 19, 2020 · 106 followers View post →
@circadianRX
@annavwellness · X

RT @nicknorwitz: Cancer & #Keto

Sep 19, 2020 · 9 shares · 3,309 followers View post →
Mary
@mbrown7311 · X

RT @nicknorwitz: Cancer & #Keto

Sep 19, 2020 · 9 shares · 296 followers View post →
nkonstas
@nkonstas · X

RT @nicknorwitz: Cancer & #Keto

Sep 19, 2020 · 9 shares · 267 followers View post →
Pixapins
@Pixapins_Docker · X

RT @nicknorwitz: Cancer & #Keto

Sep 19, 2020 · 9 shares · 1,241 followers View post →
Nick Norwitz MD PhD
@nicknorwitz · X

Cancer & #Keto

Sep 19, 2020 · 37 likes · 9 shares · 109,680 followers View post →
Dr. Websternator
@Chris_Lavina · X

@ronjdaugherty29 @GarrettIsVibin https://t.co/9cwW8CLWWE https://t.co/b5TLamjxas https://t.co/pvA1dZffH0 https://t.co/w5yuhCs4gj https://t.co/4kfDzwkqEl https://t.co/UZpLNMqLib

Aug 2, 2020 · 495 followers View post →
Dr. Websternator
@Chris_Lavina · X

@GarrettIsVibin Like I said, works on a lot not all. But considering we can create organs factories with perfectly matching DNA if not for bs "ethics" yeah my statement stands. https://t.co/9cwW8CLWWE https://t.co/b5TLamjxas https://t.co/pvA1dZffH0 https://t.co/Bd3kIGg1C2

Aug 2, 2020 · 4 likes · 495 followers View post →
MorozkoForge
@MorozkoForge · X

@jurodivi @sgcarney @seagertp @Iceman_Hof @bengreenfield @GritCoachMd @dietsloseweight @UpTalkPodcast Ketones are natural chemotherapy -- e.g., metastatic cancers inhibited. https://t.co/sMy5ueuNGN Deliberate cold exposure clears glucose from blood, starving cancer cells, and shifts metabolism to ketone production, killing tumors. Cold = double whammy for cancer.

Jan 29, 2020 · 3 likes · 2,360 followers View post →
MorozkoForge
@MorozkoForge · X

@Mangan150 Moreover, the ketones produced by his brown fat metabolism are toxic to metastasizing cancer cells. https://t.co/sMy5uedcPf Ketones are your body's natural chemotherapy, so activation of brown fat both starves cancer cells AND poisons them. @Mangan150

Dec 20, 2019 · 3 likes · 1 share · 2,360 followers View post →
AKA_Sadrien
@AKA_Sadrien · X

@IamBreastCancer https://t.co/EhddZa5Ge7 "The Ketogenic Diet Is an Effective Adjuvant to Radiation Therapy for the Treatment of Malignant Glioma " https://t.co/1xRaukCB9F Ketone supplementation reduces tumor cell viability and prolongs survival in a mouse model of metastatic cancer.

Sep 24, 2019 · 1 like · 792 followers View post →
Petra Sartor
@northstar730 · X

RT @KetoScience: Ketone administration elicited anticancer effects in vitro and in vivo independent of glucose levels or calorie restrictio…

May 28, 2019 · 1 share · 571 followers View post →
KetoScience
@KetoScience · X

Ketone administration elicited anticancer effects in vitro and in vivo independent of glucose levels or calorie restriction. #cancer #keto #science https://t.co/3t1DeHiLnZ

May 28, 2019 · 6 likes · 1 share · 668 followers View post →
Ruben Murcia Prieto
@RubenMurciaPrie · X

Poff AM et al. Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer. Abdelwahab MG et al. The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma.

Apr 2, 2019 · 8,878 followers View post →
C.R.S.
@IndependentText · X

RT @KetoScience: Ketone administration elicited anticancer effects in vitro and in vivo independent of glucose levels or calorie restrictio…

Feb 28, 2019 · 1 share · 307 followers View post →
KetoScience
@KetoScience · X

Ketone administration elicited anticancer effects in vitro and in vivo independent of glucose levels or calorie restriction. #cancer #keto #science https://t.co/3t1DeHiLnZ

Feb 28, 2019 · 2 likes · 1 share · 668 followers View post →