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The discussions predominantly support the idea that energy deficits, rather than high protein intake, drive decreases in hormones like testosterone and IGF-1, with some explicit references to scientific studies and hormonal mechanisms. The tone remains analytical and evidence-based, reflecting a scientific interest and moderate engagement while emphasizing that managing caloric intake is more impactful than adjusting protein levels.
Most discussions concur that high protein diets do not influence testosterone or IGF-1 levels during energy deficits, emphasizing the role of calorie intake over protein consumption.
Participants show moderate interest, focusing on technical details about hormonal responses rather than broader implications.
Posts reference specific studies and discuss biological mechanisms, indicating a reasonable level of engagement beyond surface-level opinions.
The consensus underscores the importance of caloric balance over protein intake in hormonal regulation, indicating moderate practical relevance for dietary strategies.
@DrAseemMalhotra High protein diets do not impact testosterone in humans, not even in an energy deficit https://t.co/cQRigdSdaB
@ScepticalDoctor Higher protein diets do not appear to stimulate IGF1 in humans when in energy deficit. Just don’t overeat https://t.co/cQRigdSdaB
@Alecsplaining @nick_krontiris @TheBhupiThakur @JohnSpeakman4 @SamueleMarcora @drmatthewnagra @NutritionMadeS3 @AlexJLeaf @TheAlanAragon @The_Nutrivore @MattMadore576 Sure, but in humans, every deficit and exercise both help attenuate igf1. It may be that the effects are due to igf1 resistance as a result of chronic over feeding, to include protein. https://t.co/cQRigdSdaB
@TheAlanAragon @shunyata2000 @tednaiman @JohnSpeakman4 @CaloriesProper @The_Nutrivore @TheBhupiThakur @nick_krontiris @SamueleMarcora @drmatthewnagra @NutritionMadeS3 @AlexJLeaf @MattMadore576 Right, in humans, igf1 decrements are not attenuated by dietary protein if in an energy deficit. My bias is eat an energy appropriate diet, in this case, a deficit, and then eat optimal protein to preserve lean body mass https://t.co/cQRigdSdaB
@toughpeoplelast Also, in humans, eating more protein within the confines of an energy deficit does not increase IGF1 The energy deficit/CR is the key https://t.co/cQRigdSdaB
@Stock_Zen Sure, although, many people speculate that it’s reduced igf1 from less meat that matter, but in an energy deficit, in humans, higher protein doesn’t elevate igf1 Meaning, it’s likely the deficit more so than the foods they do or don’t eat https://t.co/cQRigdSdaB
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@Camsbackupacct @sethweathers @nurseliz78 @elonmusk @KanekoaTheGreat No. Shawn Baker and these other carnivore gurus work out constantly and their testosterone was lower than an elderly woman's testosterone. High protein doesn't increase testosterone, stop falling for marketing bs. https://t.co/qaVF1KvIJu
@ScepticalDoctor Higher protein diets do not appear to stimulate IGF1 in humans when in energy deficit. Just don’t overeat https://t.co/cQRigdSdaB
@Plant_proof @kevinnbass @LuigiFontana22 Agreed. Plus exercise selectively activates mtor Imin brain and skeletal muscle while giving igf1 a beneficial target. Also, in humans, within the confines of an energy deficit, increased protein doesn’t seem to attenuate igf 1 decrements https://t.co/cQRigdSdaB
@toughpeoplelast Also, in humans, eating more protein within the confines of an energy deficit does not increase IGF1 The energy deficit/CR is the key https://t.co/cQRigdSdaB
@TheAlanAragon @shunyata2000 @tednaiman @JohnSpeakman4 @CaloriesProper @The_Nutrivore @TheBhupiThakur @nick_krontiris @SamueleMarcora @drmatthewnagra @NutritionMadeS3 @AlexJLeaf @MattMadore576 Right, in humans, igf1 decrements are not attenuated by dietary protein if in an energy deficit. My bias is eat an energy appropriate diet, in this case, a deficit, and then eat optimal protein to preserve lean body mass https://t.co/cQRigdSdaB
@DrAseemMalhotra High protein diets do not impact testosterone in humans, not even in an energy deficit https://t.co/cQRigdSdaB
@Stock_Zen Sure, although, many people speculate that it’s reduced igf1 from less meat that matter, but in an energy deficit, in humans, higher protein doesn’t elevate igf1 Meaning, it’s likely the deficit more so than the foods they do or don’t eat https://t.co/cQRigdSdaB
@Alecsplaining @nick_krontiris @TheBhupiThakur @JohnSpeakman4 @SamueleMarcora @drmatthewnagra @NutritionMadeS3 @AlexJLeaf @TheAlanAragon @The_Nutrivore @MattMadore576 Sure, but in humans, every deficit and exercise both help attenuate igf1. It may be that the effects are due to igf1 resistance as a result of chronic over feeding, to include protein. https://t.co/cQRigdSdaB
@303 It’s energy deficit in general, doent matter if you fast. If you IF but at the end of the day eat to maintenance then you won’t have a deficit in energy so you won’t have a diet induced reduction https://t.co/cQRigdSdaB
@HeyLougle There is an decrement to anabolic hormone production in response to energy deficit. Fasting in a net energy deficit doesn’t get around this https://t.co/cQRigdSdaB
@Paotle3 @JTMarlin77 @geoffreywoo In humans, igf1 is not elevated by increased protein within the confines of an energy deficit. The energy deficit alone appears to be the driver. It’s likely when you are in energy surplus that excess protein may matter https://t.co/cQRigdSdaB
@MountainVisions @vincentninja68 Igf signaling isn’t increased by higher protein diets in humans unless they are in caloric surplus The best course of action for humans is likely to not overeat in totally while eating enough protein to build and maintain muscle mass https://t.co/cQRigdSdaB
@gooch_steven Humans have much better cancer surveillance than rats so protein would be even less of a concern for humans. If you are still worried about IGF1/mTOR from protein here is a human study showing higher protein doesn’t increase igf1 in an energy deficit https://t.co/cQRigdSdaB
Human study showing high protein within the confines of caloric restriction not raising igf1/ testosterone https://t.co/cQRigdSdaB
RT @jerryteixeira: @vhfinn @MuscleScience Increasing protein doesn’t seem to impact igf1 in humans in an energy deficit. Spending time in a…
@BobKerner3 In addition, in humans, increasing protein intake does not elevate igf1 in an energy deficit. They key is to not overeat dietary energy, and make sure to get adequate protein. I shoot for .8g per lb bodyweight. I don’t see a point to going higher https://t.co/cQRigdSdaB
@LittleNonsuch Although, as long as you are in a net energy deficit protein has no effects on anabolic hormone production (test and igf1) so I think it’s a much greater concern in energy surplus https://t.co/cQRigdSdaB
@MonicaRicci @TestosteroneTri @JoseAntonioPhD @mackinprof Most likely, in humans increasing protein within the confines of an energy deficit has no effect on anabolic hormones https://t.co/cQRigdSdaB
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