Psychopharmacology (Berl) October 2014 PMID 24728603

MDMA alters emotional processing and facilitates positive social interaction.

Margaret C Wardle, Harriet de Wit

Mentions

8
Peak: 2 in Nov 2022
across 3 sources since Nov 2020

Extended reach

20,211
potential audience

Total likes

12

Video views

977

Mentions per month

Nov 2020 – Oct 2023

Where it's discussed

  • X / Twitter3 posts
  • News3 articles
  • YouTube2 videos

AI synopsis

What people are saying

Discussions reflect a keen interest in the social and emotional effects of MDMA, with users mentioning specific studies about face recognition and prosocial behaviors, using terms like 'facilitates' and 'promotes' to emphasize the significance. The tone suggests both curiosity and cautious acknowledgment of the potential applications, demonstrating moderate engagement and recognition of the article's impact.

AgreementModerate agreement

Most discussions acknowledge the article's findings, especially on MDMA's role in enhancing positive social interactions and emotional perception.

InterestHigh interest

Participants show high curiosity about the implications of altered emotional processing, with mentions of related studies and neurochemical mechanisms.

EngagementModerate engagement

Comments reference specific research details, such as face recognition impairments and comparisons with substances like oxytocin, indicating moderate depth of discussion.

ImpactHigh impact

The conversation hints at significant implications for therapy and social behavior, aligned with statements about MDMA's potential uses and its social effects.

Abstract in brief

  • MDMA enhances prosocial feelings like empathy and closeness by altering how we perceive and respond to emotional expressions, particularly by slowing the recognition of negative (angry) cues and amplifying positive responses to happy cues.
  • During social interactions, MDMA increases positive language and perceptions of partner empathy and regard, suggesting it promotes more positive social behavior and connection.
  • While these emotional and social effects could explain MDMA's usefulness in therapy, they don't seem to be directly linked to its potential for abuse, as the desire to take the drug again wasn't strongly connected to these emotional changes.]

Top posts

Most liked on X and Bluesky
Manoj Doss not exist
@ManojDoss · X

@SashaSisko @GillBedi @m_wall @EricFeczko @MGirnNeuro ...several studies find impaired recognition of fearful and angry faces (and sometimes sad faces) but not happy faces: https://t.co/IMJXZix27m https://t.co/MkPXbWOlYZ https://t.co/aF4oFKI22F https://t.co/q2CnO8LCKX https://t.co/qddd5rWhwn https://t.co/iYjbv1Ec39

Oct 31, 2023 · 1 like · 6,085 followers View post →
Kintsugi
@K1ntsu61 · X

Social proximity is important. In a similarly designed test, they may have concluded oxytocin doesn't promote prosocial behaviours. https://t.co/ACFnqILrui https://t.co/646gEsW1P1 https://t.co/PiCJoUa1pL https://t.co/ev76koCXu8 https://t.co/ZiOf660yZb https://t.co/hPNTqln46K

Nov 24, 2020 · 1 like · 1,121 followers View post →

All mentions

Manoj Doss not exist
@ManojDoss · X

@SashaSisko @GillBedi @m_wall @EricFeczko @MGirnNeuro ...several studies find impaired recognition of fearful and angry faces (and sometimes sad faces) but not happy faces: https://t.co/IMJXZix27m https://t.co/MkPXbWOlYZ https://t.co/aF4oFKI22F https://t.co/q2CnO8LCKX https://t.co/qddd5rWhwn https://t.co/iYjbv1Ec39

Oct 31, 2023 · 1 like · 6,085 followers View post →
Anastasie
@Psychanastasie · X

MDMA alters emotional processing and facilitates positive social interaction [Margaret C Wardle, Harriet de Wit, Psychopharmacology (Berl). 2014 Oct;231(21):4219-29. doi: 10.1007/s00213-014-3570-x] https://t.co/gyFxOeuCzz https://t.co/42yRk4Hv6q

Jul 1, 2021 · 11,999 followers View post →
Kintsugi
@K1ntsu61 · X

Social proximity is important. In a similarly designed test, they may have concluded oxytocin doesn't promote prosocial behaviours. https://t.co/ACFnqILrui https://t.co/646gEsW1P1 https://t.co/PiCJoUa1pL https://t.co/ev76koCXu8 https://t.co/ZiOf660yZb https://t.co/hPNTqln46K

Nov 24, 2020 · 1 like · 1,121 followers View post →
Review Article - MDMA for treatment of PTSD and ...
News

https://doi.org/10.1007/s00213-014-3570-x. Warraich, Z., & Kleim, J. A. (2010). Neural plasticity: the bio- logical substrate for neurorehabilitation. PM R ...

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Savedrecs | PDF | Substance Use Disorder | Opioid Use Disorder
News

10.1007/s00213-014-3570-x; Ware JE, 1996, MED CARE, V34, P220, DOI 10.1097/00005650-199603000-00003 63 0 0 0 1 ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD ...

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Dec 12, 2025 View →