Forensic Sci Int July 2014 PMID 24769343

Xylazine intoxication in humans and its importance as an emerging adulterant in abused drugs: A comprehensive review of the literature.

Kazandra Ruiz-Colón, Carlos Chavez-Arias, José Eric Díaz-Alcalá, María A Martínez

Mentions

44
Peak: 2 in Jun 2023
across 4 sources since Sep 2021

Extended reach

138,847
potential audience

Total likes

13

Video views

813

Mentions per month

Sep 2021 – Apr 2024

Where it's discussed

  • News33 articles
  • X / Twitter5 posts
  • Blogs4 articles
  • YouTube2 videos

AI synopsis

What people are saying

The posts reflect a general acknowledgment of the article’s importance, with mentions of physical deterioration, skin ulcers, and the dangers of xylazine as a cutting agent. Words like 'important,' 'dangerous,' and references to its veterinary use convey a tone of concern and awareness, emphasizing the potential health impact, but the overall reaction remains relatively measured, indicating moderate engagement and interest.

AgreementNeither agree nor disagree

The posts recognize the importance of the article and acknowledge its relevance, but do not show strong consensus or disagreement.

InterestModerate interest

Most discussions indicate moderate interest, particularly around the health risks and the drug's adulteration as a concern.

EngagementModerate engagement

Participants discuss specific details, such as the health consequences and the drug's use in veterinary medicine, reflecting some depth of engagement.

ImpactModerate impact

The discussions highlight awareness of xylazine’s dangers and its rising prevalence, suggesting moderate perceived impact on public health and safety.

Abstract in brief

  • Xylazine, a veterinary sedative not controlled as a drug, can cause serious health issues in humans including central nervous system depression, respiratory depression, bradycardia, hypotension, and death, with 43 reported cases—about half fatal.
  • Recently, xylazine has increasingly been found as an adulterant in illicit drugs like heroin and cocaine, often contributing to physical deterioration and skin ulcers in users, and potentially increasing the risk of fatalities due to synergistic toxic effects.
  • A comprehensive review of nonfatal and fatal xylazine intoxication cases aims to raise awareness among forensic, law enforcement, and public health communities about its dangers as an adulterant and its harmful effects when combined with other drugs.

Top posts

Most liked on X and Bluesky
Samantha Adcock
@hope411adcock · X

@Nashkitty66 @secondchances09 @PhilipFDaniels1 @CContrarus @bluelilly40 @SarahSaysHi2U @RobertC94894966 @Vlynx5 @kris_lovaas @femme_phememe @EbCummings1 @SpicyPurritos @onnaroll66 @lakeparkcpl @Chronic_FLKeys @soofriends @chattyknana @HR4peopleinpain @NAbleism @Melothrien @EverydayAgony @Irishbrat1966 @aander1987 @ThomasKlineMD @Thinktank1979 @eullrich11 @JustWinks @StopBadDocs @headdock @KimmMathiesen @JSG_54 @NitaGhei @DebM01279692 @GEugenics @sky_dvr @dau1776 @OpioidHysteria @wittywax1 @ChadDKollas @process_x @ibdgirl76 @WriterMera @TheDarkGift_ @lockedoutofvenu @Deeenst @Canada_NV @maryann19711 @Royalacresrod @life_is_art___ @fightpaindaily It's only approved for use in animals. https://t.co/JC0R2qvZFW https://t.co/RDAdoOKq6o

Sep 17, 2021 · 5 likes · 1,858 followers View post →
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

@SiberianYog @BowTiedLoon Literally first result on Google https://t.co/fZIV3JqFdn “Its chronic use is reported to be associated with physical deterioration and skin ulceration.” Took two seconds.

Jun 15, 2023 · 2 likes · 133,502 followers View post →
Dr. Michael Schatman
@headdock · X

Ruiz-Colón K, Chavez-Arias C, Díaz-Alcalá JE, Martínez MA. Xylazine intoxication in humans and its importance as an emerging adulterant in abused drugs: A comprehensive review of the literature. Forensic Sci Int. 2014 Jul;240:1-8. https://t.co/Uq5TyWa2mg

Feb 14, 2023 · 2,254 followers View post →
ToneyDomPérignon
@Tenderoni_Toney · X

@BBMolasses Xylazine is marketed as a veterinary drug and used as a sedative, analgesic and muscle relaxant. In humans, it could cause central nervous system depression, respiratory depression, bradycardia, hypotension, and even death. https://t.co/xBJshlqgwx

Aug 10, 2022 · 324 followers View post →

All mentions

Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

@SiberianYog @BowTiedLoon Literally first result on Google https://t.co/fZIV3JqFdn “Its chronic use is reported to be associated with physical deterioration and skin ulceration.” Took two seconds.

Jun 15, 2023 · 2 likes · 133,502 followers View post →
yungblinkerfluid
@sleeze0333 · X

@licensetoshill @Alektsander @DailyLoud Here's even an article about xylazine before it was becoming "popular" in other drugs as a cutting agent. https://t.co/9P5s3I1eEj

May 16, 2023 · 97 followers View post →
Dr. Michael Schatman
@headdock · X

Ruiz-Colón K, Chavez-Arias C, Díaz-Alcalá JE, Martínez MA. Xylazine intoxication in humans and its importance as an emerging adulterant in abused drugs: A comprehensive review of the literature. Forensic Sci Int. 2014 Jul;240:1-8. https://t.co/Uq5TyWa2mg

Feb 14, 2023 · 2,254 followers View post →
ToneyDomPérignon
@Tenderoni_Toney · X

@BBMolasses Xylazine is marketed as a veterinary drug and used as a sedative, analgesic and muscle relaxant. In humans, it could cause central nervous system depression, respiratory depression, bradycardia, hypotension, and even death. https://t.co/xBJshlqgwx

Aug 10, 2022 · 324 followers View post →
Samantha Adcock
@hope411adcock · X

@Nashkitty66 @secondchances09 @PhilipFDaniels1 @CContrarus @bluelilly40 @SarahSaysHi2U @RobertC94894966 @Vlynx5 @kris_lovaas @femme_phememe @EbCummings1 @SpicyPurritos @onnaroll66 @lakeparkcpl @Chronic_FLKeys @soofriends @chattyknana @HR4peopleinpain @NAbleism @Melothrien @EverydayAgony @Irishbrat1966 @aander1987 @ThomasKlineMD @Thinktank1979 @eullrich11 @JustWinks @StopBadDocs @headdock @KimmMathiesen @JSG_54 @NitaGhei @DebM01279692 @GEugenics @sky_dvr @dau1776 @OpioidHysteria @wittywax1 @ChadDKollas @process_x @ibdgirl76 @WriterMera @TheDarkGift_ @lockedoutofvenu @Deeenst @Canada_NV @maryann19711 @Royalacresrod @life_is_art___ @fightpaindaily It's only approved for use in animals. https://t.co/JC0R2qvZFW https://t.co/RDAdoOKq6o

Sep 17, 2021 · 5 likes · 1,858 followers View post →