May 2014 PMID 24838074

Ultraviolet radiation, aging and the skin: prevention of damage by topical cAMP manipulation.

Alexandra Amaro-Ortiz, Betty Yan, John A D'Orazio

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Mentions

16
Peak: 2 in Dec 2020
across 4 sources since Jul 2019

Extended reach

18,506
potential audience

Total likes

54

Video views

1,194

Mentions per month

Jul 2019 – Apr 2025

Where it's discussed

  • News9 articles
  • X / Twitter3 posts
  • YouTube2 videos
  • Instagram2 posts

AI synopsis

What people are saying

The discussions highlight the importance of UV protection and the potential of topical cAMP manipulation, with examples like references to forskolin's traditional uses and its role in enhancing pigmentation, demonstrating a keen interest and engagement with the scientific implications and future applications of the research.

AgreementModerate agreement

Most discussions acknowledge the significance of the research, emphasizing the potential of cAMP manipulation and natural compounds like forskolin in protecting against UV-induced skin damage.

InterestHigh interest

The discussions demonstrate high interest by referencing specific mechanisms, such as pigmentation and skin aging, and citing the publication directly.

EngagementModerate engagement

Participants engage with the topic by referencing the study, mentioning traditional medicinal uses, and analyzing potential practical applications, indicating moderate to deep engagement.

ImpactModerate impact

The discussions suggest that the publication could influence future research and skin protection strategies, though the impact appears to be in early stages of influence.

Abstract in brief

  • Ultraviolet (UV) radiation causes skin damage through inflammation, DNA impairment, and increased risk of aging and skin cancer such as melanoma, which is particularly prevalent in individuals over 55.
  • The review explores natural protective mechanisms against UV damage, including the potential use of forskolin, a plant-derived compound, to enhance melanin production and reduce UV injury when applied topically.
  • Forskolin, obtained from the Plectranthus barbatus plant, has traditional medicinal uses and is considered for preventing photoaging and skin cancer by upregulating protective responses like increased pigmentation.

Top posts

Most liked on X and Bluesky
fée de la skincare
@HOELANl · X

8- Amaro-Ortiz A, Yan B, D'Orazio JA. Ultraviolet radiation, aging and the skin: prevention of damage by topical cAMP manipulation. Molecules. 2014;19(5):6202-6219. Published 2014 May 15. doi:10.3390/molecules19056202

Jul 25, 2022 · 11 likes · 1 share · 14,132 followers View post →
Le PSG me rend heureuse
@UmmuLayan · X

RT @HOELANl: 8- Amaro-Ortiz A, Yan B, D'Orazio JA. Ultraviolet radiation, aging and the skin: prevention of damage by topical cAMP manipula…

Jul 26, 2022 · 1 share · 2,678 followers View post →

All mentions

Le PSG me rend heureuse
@UmmuLayan · X

RT @HOELANl: 8- Amaro-Ortiz A, Yan B, D'Orazio JA. Ultraviolet radiation, aging and the skin: prevention of damage by topical cAMP manipula…

Jul 26, 2022 · 1 share · 2,678 followers View post →
fée de la skincare
@HOELANl · X

8- Amaro-Ortiz A, Yan B, D'Orazio JA. Ultraviolet radiation, aging and the skin: prevention of damage by topical cAMP manipulation. Molecules. 2014;19(5):6202-6219. Published 2014 May 15. doi:10.3390/molecules19056202

Jul 25, 2022 · 11 likes · 1 share · 14,132 followers View post →
jelly
@jellybal · X

"Ultraviolet Radiation, Aging and the Skin: Prevention of Damage by Topical cAMP Manipulation" (2014) https://t.co/ojdLo2WF0r

Jul 1, 2019 · 388 followers View post →
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(2014). New insights in photoaging, UVA induced damage and skin types. (5), 6202–6219. doi:10.3390/molecules19056202 Exp. Dermatol.

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