PubHawk
June 2014 PMID 24840803

Obsessive-compulsive disorder: an integrative genetic and neurobiological perspective.

David L Pauls, Amitai Abramovitch, Scott L Rauch, Daniel A Geller

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Mentions

61
Peak: 1 in Oct 2019
across 4 sources since Oct 2019

Extended reach

1,030,248
potential audience

Total likes

9,313

Video views

1,024,791

Mentions per month

Oct 2019 – Feb 2024

Where it's discussed

  • News53 articles
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  • YouTube2 videos
  • X / Twitter1 posts

AI synopsis

What people are saying

Discussions demonstrate strong interest and moderate agreement, with comments highlighting the significance of the neural circuits involved in OCD and the role of genetics, such as mentions of genes related to serotonin, dopamine, and glutamate systems. The tone is analytical yet optimistic about the article's potential to advance understanding, with phrases like ‘groundbreaking’ and ‘could reshape treatment strategies’ illustrating perceived impact.

AgreementModerate agreement

Most discussions express support or alignment with the publication's insights, emphasizing the importance of genetic and neurobiological perspectives.

InterestHigh interest

Posts show high interest, with many praising the comprehensive nature of the research and its implications for understanding OCD.

EngagementModerate engagement

Participants actively analyze the neurobiological mechanisms and potential therapeutic implications, indicating moderate deep engagement.

ImpactModerate impact

The discourse suggests that the article could influence future research directions and clinical approaches, but remains somewhat preliminary.

Abstract in brief

  • Obsessive-compulsive disorder (OCD) involves unwanted repetitive thoughts and behaviors, influenced by a combination of genetic, environmental, and neurobiological factors.
  • Neuroimaging highlights the cortico-striatothalamocortical circuit as key in OCD, with patients showing impairments in executive functions linked to this neural pathway, while genetic research points to genes related to serotonin, dopamine, and glutamate systems.
  • Environmental influences like trauma or adverse events can alter gene expression, potentially triggering OCD symptoms by affecting the brain's neurobiological pathways.]
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Top posts

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Debunking Denialism
@debunkdenialism · X

@CapitalistFraud Obsessive-compulsive disorder: an integrative genetic and neurobiological perspective https://t.co/no1hRhh8U4

Oct 3, 2019 · 5,457 followers View post →

All mentions

Debunking Denialism
@debunkdenialism · X

@CapitalistFraud Obsessive-compulsive disorder: an integrative genetic and neurobiological perspective https://t.co/no1hRhh8U4

Oct 3, 2019 · 5,457 followers View post →