Synopsis of Social media discussions

Discussions reveal a strong interest in the possibility that metformin could extend lifespan, exemplified by users mentioning specific studies like Bannister et al. (2014) and the TAME trial, and expressing curiosity about its broader health effects, with a tone that balances skepticism and optimism that signals meaningful engagement and recognition of impact.

A
Agreement
Moderate agreement

Most discussions support the idea that metformin may promote longevity, referencing studies like Bannister et al. (2014) and the TAME trial, though some express skepticism about the extrapolation to non-diabetics.

I
Interest
High level of interest

Posts show high curiosity, with many referencing videos explaining metformin's potential, and users actively engaging with study details and implications.

E
Engagement
High engagement

Participants analyze the study's findings, question causation versus correlation, and discuss potential benefits beyond diabetes management, indicating deep engagement.

I
Impact
Moderate level of impact

While some see the findings as potentially transformative, especially given the cost-effectiveness of the drug, others remain cautious, reflecting moderate perceived impact before definitive proof.

Social Mentions

YouTube

7 Videos

Bluesky

1 Posts

Facebook

18 Posts

Twitter

97 Posts

Blogs

17 Articles

News

59 Articles

Reddit

2 Posts

Metrics

Video Views

1,728,954

Total Likes

40,825

Extended Reach

2,940,926

Social Features

201

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

Exploring Metformin: Anti-Aging Potential and Current Research

Exploring Metformin: Anti-Aging Potential and Current Research

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August 31, 2023

152,060 views


Exploring Aging Pathways: Lifestyle, Diet, and Autophagy Insights

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Recent research has advanced our understanding of aging mechanisms and their effects on longevity. This video examines multiple strategies, including lifestyle and diet, that could enhance healthspan by interacting with autophagy and other pathways. Discover insights backed by 36 studies.

July 25, 2020

114,522 views


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December 6, 2023

74,072 views


Metformin and Sulphonylurea Impact on Mortality and Longevity

Metformin and Sulphonylurea Impact on Mortality and Longevity

The study investigates whether increased cardiovascular risk and mortality in diabetes patients are due to sulphonylureas or benefits of metformin. Data shows metformin users have better survival rates than non-diabetics, while sulphonylurea users have reduced survival. Learn more about these effects.

June 26, 2024

49,656 views


Metformin's Impact on Longevity in Type 2 Diabetes Patients

Metformin's Impact on Longevity in Type 2 Diabetes Patients

This study compares mortality rates of type 2 diabetes patients treated with metformin or sulphonylureas to non-diabetic controls, highlighting potential benefits of metformin for longevity and the risks associated with sulphonylureas.

December 28, 2023

15,677 views


Understanding Aging: Biological, Systemic, and Statistical Perspectives

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This video explores the question why we age at four levels of complexity using stories, biology, statistics, and systems biology to provide a comprehensive understanding of aging.

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215 views


  • Adam Galas
    @adamgalas.bsky.social (Bluesky)

    youtu.be/sFbghkE0WYo?... This is one of the cheapest and most effective drugs on Earth but of course there is no magic pill.
    view full post

    August 21, 2025

    1

  • Chuck Frasher
    @ChuckFrasher (Twitter)

    @davidasinclair David Sinclair https://t.co/vmbdCFyeCN https://t.co/VN6ibzEpKv https://t.co/U0BkU1irZP https://t.co/44NfnvGi3Z https://t.co/Jp5fOjhBcb https://t.co/XjhwQ2ELzi https://t.co/eZ8m3IO72D
    view full post

    July 18, 2025

  • Chuck Frasher
    @ChuckFrasher (Twitter)

    @siimland @davidasinclair https://t.co/vmbdCFyeCN https://t.co/VN6ibzEpKv https://t.co/U0BkU1irZP https://t.co/44NfnvGi3Z https://t.co/Jp5fOjhBcb https://t.co/XjhwQ2ELzi https://t.co/eZ8m3IO72D
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    July 18, 2025

  • Hopehood.org
    @dotails (Twitter)

    ## Immortality Theater Nobody knows what works best for your body, but we can't let anything keep us from trying our best. Here's some ideas about health I've found. https://t.co/abmxIr13f4
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    May 22, 2025


  • @teel0ck (Twitter)

    Metformin, the Big New "Anti-Aging" Drug, Explained https://t.co/Ik5kcNlqRw via @YouTube
    view full post

    April 30, 2025

  • 赤い炊飯ジャー(shin1_s)
    @shin1_s (Twitter)

    Can people with type 2 diabetes live longer than those without? https://t.co/ljTM5jyM0A
    view full post

    April 21, 2025

  • waz
    @_waztra (Twitter)

    https://t.co/eiY0ued5YL
    view full post

    January 8, 2025

  • Hopehood.org
    @dotails (Twitter)

    ## Immortality Theater Nobody knows what works best for your body, but we can't let anything keep us from trying our best. Here's some ideas about health I've found. https://t.co/abmxIr13f4
    view full post

    October 24, 2024

  • luis hernan graffe
    @hernangraffe (Twitter)

    https://t.co/PvVTXOFPUC
    view full post

    October 22, 2024

  • Health on a Budget
    @healthonabudget (Twitter)

    Is metformin the new anti-aging drug? https://t.co/1wpnf7YCna
    view full post

    October 20, 2024

  • DANVZLA
    @danvzla (Twitter)

    Metformin, the Big New "Anti-Aging" Drug, Explained https://t.co/VBaiykRYRE via @YouTube
    view full post

    October 3, 2024

  • Brian Goodman
    @BrianGo11111623 (Twitter)

    https://t.co/Kcbzik6jVG
    view full post

    September 16, 2024

  • BillOckham
    @BillOccham0 (Twitter)

    @Madam_Mito That’s NOT a trial but observational data 2nd It’s not true as shown here: https://t.co/UDMtnSbSge And least but MOST important - plenty of life extended signalling paths https://t.co/EiJaxjqooA
    view full post

    September 13, 2024

  • Hopehood.org
    @dotails (Twitter)

    ## Immortality Theater Nobody knows what works best for your body, but we can't let anything keep us from trying our best. Here's some ideas about health I've found. https://t.co/abmxIr13f4
    view full post

    July 18, 2024

  • luis hernan graffe
    @hernangraffe (Twitter)

    https://t.co/EyIRVweOq1
    view full post

    June 7, 2024

  • Jordan Curl
    @JordanCurlMD (Twitter)

    TAME Trial https://t.co/AfsfwUflKc Keys et al. (2022) https://t.co/9qy2Lhqvvw Bannister et al. (2014) https://t.co/GPw4bEfasD
    view full post

    May 21, 2024

    1

  • Pee Baa
    @Pee_Baaa (Twitter)

    @OkieLibSherry @EvolaVonValor @_celia_bedelia_ I guess type 2 diabetes must be healthy since they live longer if on metformin than no diabetics lol. Jfc it’s almost like medical interventions work lol.
    view full post

    December 24, 2023

  • Mind Your Science!
    @MindYourSci (Twitter)

    RT @agingdoc1: Can people with type 2 diabetes live longer than those without? A comparison of mortality in people initiated with metformin…
    view full post

    December 15, 2023

    3

  • frank
    @frankwikson (Twitter)

    RT @agingdoc1: Can people with type 2 diabetes live longer than those without? A comparison of mortality in people initiated with metformin…
    view full post

    December 14, 2023

    3

  • Agingdoc
    @agingdoc1 (Twitter)

    Can people with type 2 diabetes live longer than those without? A comparison of mortality in people initiated with metformin or sulphonylurea monotherapy and matched, non-diabetic controls (2014) https://t.co/wu0eCQfOIr
    view full post

    December 14, 2023

    3

    3

  • Yuji Marutani Planning Director
    @YujiMarutani (Twitter)

    Can people with type 2 diabetes live longer than those without? A comparison of mortality in people initiated with metformin or sulphonylurea monotherapy and matched, non‐diabetic controls - Bannister - 2014 - Diabetes, Obesity and Metabolism - Wiley https://t.co/8SeCyQOHDE
    view full post

    December 6, 2023

  • alinthemind
    @alinthemind (Twitter)

    https://t.co/clTUy2Mjv1
    view full post

    November 29, 2023

  • Alessiana
    @Alessiana (Twitter)

    RT @DavidRoweWTL: "Conclusions: Patients with type 2 diabetes initiated with metformin monotherapy had longer survival than did matched, n…
    view full post

    September 11, 2023

    1

  • DavidRowe ⧖ - Caution, you may encounter nuance.
    @DavidRoweWTL (Twitter)

    "Conclusions: Patients with type 2 diabetes initiated with metformin monotherapy had longer survival than did matched, non-diabetic controls." {From a total censored follow-up period of 503,384 years.} (Big Study). https://t.co/Mjh92gnWPT
    view full post

    September 11, 2023

    1

  • ParshPolit
    @ParshPolit (Twitter)

    @RealCandaceO I’m loving Shot in the Dark and I’m wondering what do you think about Metformin? I watched this video on it: https://t.co/x1gQfjuVTO
    view full post

    July 5, 2023

  • VAUBAN Sébastien Le Prestre
    @Vauban059 (Twitter)

    RT @AlexSamTG: La publi décrite dans le docu, c'est celle-ci : https://t.co/dTSEtaJ2C2 Elle a pratiqué un ajustement pour atteindre non pas…
    view full post

    June 1, 2023

    3

  • Sixers
    @sixers2772 (Twitter)

    @Outdoctrination
    view full post

    May 23, 2023

    1

  • Laszlo Levay Trump best president
    @levis3331 (Twitter)

    https://t.co/Yrz9HH1YGD https://t.co/Y8qLRnXQL2
    view full post

    May 15, 2023

  • Esam Shahlol, MD
    @EsamShahlol (Twitter)

    @AMCGME11 @DrAlkhodairy في الحقيقة مرضى السكر من النوع الثاني الذين يأخذون جلوكوفاج (ميتفورمين) يعيشون حياة صحية مثل أو أطول من غير المصابين بالسكر. ألمصدر: https://t.co/45LTS9zfph
    view full post

    February 24, 2023

    1

  • Genetic Health Systems
    @GeneHealthSys (Twitter)

    RT @DrBDrugDoc: Type 2 Diabetics taking Metformin lived longer than those who were not T2D. https://t.co/6R1PdWcqCO
    view full post

    February 20, 2023

    1

  • Brad Carper
    @BradPharm (Twitter)

    @ElieJarrougeMD I found this study incredible. T2D taking Metformin lived longer than those who were not T2D. https://t.co/6R1PdWcqCO
    view full post

    February 20, 2023

  • Brad Carper
    @BradPharm (Twitter)

    Type 2 Diabetics taking Metformin lived longer than those who were not T2D. https://t.co/6R1PdWcqCO
    view full post

    February 20, 2023

    1

    1


  • @HemskVampyr (Twitter)

    Hacking the 3 Pathways of Aging https://t.co/SIOH8ztLfQ via @YouTube
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    February 20, 2023

  • luis hernan graffe
    @hernangraffe (Twitter)

    RT @BradStanfieldMD: References: https://t.co/XsVPJGFAbp https://t.co/CsSaw7YzQY https://t.co/PnWNp9Z4vC https://t.co/vFVUftHdtj https://t.…
    view full post

    January 30, 2023

    4

  • Sonia Jardón V
    @sjardon_gdl (Twitter)

    RT @BradStanfieldMD: References: https://t.co/XsVPJGFAbp https://t.co/CsSaw7YzQY https://t.co/PnWNp9Z4vC https://t.co/vFVUftHdtj https://t.…
    view full post

    January 12, 2023

    4

  • John Best
    @noobestjohn (Twitter)

    RT @BradStanfieldMD: References: https://t.co/XsVPJGFAbp https://t.co/CsSaw7YzQY https://t.co/PnWNp9Z4vC https://t.co/vFVUftHdtj https://t.…
    view full post

    January 12, 2023

    4

  • Dr Brad Stanfield
    @BradStanfieldMD (Twitter)

    References: https://t.co/XsVPJGFAbp https://t.co/CsSaw7YzQY https://t.co/PnWNp9Z4vC https://t.co/vFVUftHdtj https://t.co/Vc9y4ShTTD https://t.co/lfBKrHNAO4 https://t.co/HWl72VwLiQ https://t.co/1u1oIOJ0NR
    view full post

    January 12, 2023

    33

    4

  • Peekaboo
    @PaPeekaboo (Twitter)

    RT @AlexSamTG: La publi décrite dans le docu, c'est celle-ci : https://t.co/dTSEtaJ2C2 Elle a pratiqué un ajustement pour atteindre non pas…
    view full post

    December 17, 2022

    3

  • Aude Smith
    @AudeSmith5 (Twitter)

    RT @AlexSamTG: La publi décrite dans le docu, c'est celle-ci : https://t.co/dTSEtaJ2C2 Elle a pratiqué un ajustement pour atteindre non pas…
    view full post

    December 17, 2022

    3

  • Alexander Samuel
    @AlexSamTG (Twitter)

    La publi décrite dans le docu, c'est celle-ci : https://t.co/dTSEtaJ2C2 Elle a pratiqué un ajustement pour atteindre non pas "17%" mais "15%", et c'est pas super fiable pour plein de limitations évoquées... Résultats contredits ici : https://t.co/Y0k49un93U ⬇️ https://t.co/X4Wweuz6u3
    view full post

    December 17, 2022

    30

    3

  • David Stănete
    @stanete (Twitter)

    I love Cleo Abram's idea of genuine optimism. In a world (specially on Twitter) where I see a lot of pessimism, this way of looking at technology brings fresh air. https://t.co/zn4koQqyWt
    view full post

    December 13, 2022

  • goufpeera
    @goufpeera2 (Twitter)

    https://t.co/y0ga5qu7QG
    view full post

    November 22, 2022


  • @kedarus (Twitter)

    @CJ_NFA @Openskies13 @DoctorJack16 I started to read about https://t.co/7gbDiA7A5k
    view full post

    October 17, 2022

    1

  • BATMAN
    @ChamaraVFX (Twitter)

    https://t.co/E5Unq81u3E
    view full post

    October 7, 2022


  • @Orlando_uy (Twitter)

    RT @JBlivik: Reduction of high insulin (increases linearly with obesity & exposure to diabetes care) prolongs life, halves the risk of dyin…
    view full post

    July 13, 2022

    1

  • John Blivik
    @JBlivik (Twitter)

    Reduction of high insulin (increases linearly with obesity & exposure to diabetes care) prolongs life, halves the risk of dying, & helps with weight loss (along with physical activity immediately after eating, reduced intake of animal fat & fast carbs). https://t.co/ZeNC7IleGA
    view full post

    July 13, 2022

    2

    1

  • a
    @nhxpost (Twitter)

    @llamacorn888 @VitalikButerin https://t.co/cTgEE6vc0B diabetics taking metformin live longer than healthy non-diabetics not taking it apparently
    view full post

    June 20, 2022

    1

  • Giuseppe Maltese
    @docmaltese (Twitter)

    RT @docmaltese: Can people with type 2 diabetes live longer than those without? “Patients with type 2 diabetes initiated with metformin mo…
    view full post

    May 3, 2022

    1

  • Chuck Frasher
    @ChuckFrasher (Twitter)

    @CharlesMBrenner https://t.co/VN6ibzEpKv. https://t.co/vmbdCFyeCN
    view full post

    May 1, 2022

  • Prajit
    @docprajit (Twitter)

    Correlation or Causation? Is Metformin, the big new "anti-aging" or rather prevent effects of aging drug? https://t.co/URIGg94oWo via @YouTube
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    April 24, 2022

  • Annie
    @fullinhalfout (Twitter)

    @hankgreen @cleoabram My fave one recently: https://t.co/s45r8khsSp
    view full post

    April 12, 2022

    1

  • ShibaTatsuya
    @ShibaTa50325300 (Twitter)

    @ilyassahinMD https://t.co/YW8co5YPx2 Sayın İlyas hocam, bazen benim de kullanasım gelmiyor değil.
    view full post

    April 6, 2022

  • Tomasz
    @perlyswietlne (Twitter)

    Metformin i inne leki (potencjalnie!) opóźniające starzenie się.
    view full post

    April 3, 2022

  • Philosophy And Math
    @philosophy_math (Twitter)

    Liked on YouTube: Metformin, the big new "anti-aging" drug, explained https://t.co/Ni5czf2rLE
    view full post

    April 3, 2022

  • 曾嘉俊 Zeng Jiajun
    @zengjiajun_eth (Twitter)

    Metformin, the big new "anti-aging" drug, explained https://t.co/qou0XJ0eEZ via @YouTube
    view full post

    March 21, 2022

    1

  • ProjectOneWorldLearn
    @OneWorldSchool1 (Twitter)

    Metformin, the big new "anti-aging" drug, explained https://t.co/mCMkqn6EHr via @YouTube
    view full post

    March 21, 2022

  • Pelayo Prieto
    @PelayoPrieto (Twitter)

    ¿Y si un fármaco barato, conocido desde hace años para tratar la diabetes pudiera retrasar nuestro envejecimiento? Más importante aún : ¿Y si nos permitiera pasar más tiempo con los que más queremos? https://t.co/MvLWnM5JvA vía @cleoabram
    view full post

    March 15, 2022

  • SortaRican
    @vaughnp (Twitter)

    The new way billionaires try to live longer https://t.co/xaXlfuPxMX via @YouTube
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    February 5, 2022

  • MediaREDEF
    @MediaREDEF (Twitter)

    The new way billionaires try to live longer (@cleoabram) https://t.co/4hG5hXLzNH
    view full post

    February 4, 2022


  • @teel0ck (Twitter)

    The new way #billionaires try to live longer https://t.co/tr2biBmlH2 via @YouTube
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    February 4, 2022

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    @SachinMourya6 (Twitter)

    RT @cleoabram: To try to live longer, billionaires are taking a pill that costs pennies. So, uh… does it work?
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    February 4, 2022

    10

  • How to Change Your Self
    @iamdeandwyer (Twitter)

    RT @cleoabram: To try to live longer, billionaires are taking a pill that costs pennies. So, uh… does it work?
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    February 4, 2022

    10

  • Show Me Strength
    @ShowMeStrength (Twitter)

    The mainstream finally catching up to what @JayCampbell333 has been saying for years https://t.co/qV1JG6aWxa
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    February 4, 2022

  • HouseOfOchii
    @OchiiOgango (Twitter)

    RT @cleoabram: To try to live longer, billionaires are taking a pill that costs pennies. So, uh… does it work?
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    February 4, 2022

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  • Abhishek Patil
    @oldtrafford007 (Twitter)

    The new way billionaires try to live longer https://t.co/vJC5Nmhcu4 via @YouTube
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    February 4, 2022

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  • wachira
    @__wchr (Twitter)

    Great video by @cleoabram to end the week https://t.co/WPUFJOIZW9
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    February 4, 2022

  • RiskReversal Media
    @RiskReversal (Twitter)

    RT @cleoabram: To try to live longer, billionaires are taking a pill that costs pennies. So, uh… does it work?
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    February 3, 2022

    10

  • ricardosharing
    @ricardosharing (Twitter)

    The cheap drug rich people take to live longer https://t.co/P5U081zfdo
    view full post

    February 2, 2022

  • Nestor Lagos Borda
    @DxNESTORxD (Twitter)

    RT @cleoabram: To try to live longer, billionaires are taking a pill that costs pennies. So, uh… does it work?
    view full post

    February 2, 2022

    10

  • Rob Schutz
    @rob (Twitter)

    RT @cleoabram: To try to live longer, billionaires are taking a pill that costs pennies. So, uh… does it work?
    view full post

    February 1, 2022

    10

  • Z Reitano
    @ZReitano (Twitter)

    RT @cleoabram: To try to live longer, billionaires are taking a pill that costs pennies. So, uh… does it work?
    view full post

    February 1, 2022

    10

  • ntapia
    @ntapia (Twitter)

    @JEverettLearned https://t.co/Lq9sfhBHEC
    view full post

    February 1, 2022

  • Louis Anslow
    @LouisAnslow (Twitter)

    RT @cleoabram: To try to live longer, billionaires are taking a pill that costs pennies. So, uh… does it work?
    view full post

    February 1, 2022

    10

  • Garry Tan
    @garrytan (Twitter)

    RT @cleoabram: To try to live longer, billionaires are taking a pill that costs pennies. So, uh… does it work?
    view full post

    February 1, 2022

    10

  • Louis Anslow
    @LouisAnslow (Twitter)

    RT @statto: Entertained to see that I got a (very tiny!) cameo in @cleoabram’s new video on anti-aging drug metformin! And it’s a great vi…
    view full post

    February 1, 2022

    2

  • Cleo Abram
    @cleoabram (Twitter)

    RT @statto: Entertained to see that I got a (very tiny!) cameo in @cleoabram’s new video on anti-aging drug metformin! And it’s a great vi…
    view full post

    February 1, 2022

    2

  • Andrew Steele
    @statto (Twitter)

    Entertained to see that I got a (very tiny!) cameo in @cleoabram’s new video on anti-aging drug metformin! And it’s a great video whose conclusion I completely agree with. I get asked about metformin all the time and this is basically what I say: https://t.co/SAsrIxuueb
    view full post

    February 1, 2022

    7

    2

  • Nicholas (Sedgewick) Thompson
    @niksthompson (Twitter)

    RT @cleoabram: To try to live longer, billionaires are taking a pill that costs pennies. So, uh… does it work?
    view full post

    February 1, 2022

    10

  • JULES
    @julesterpak (Twitter)

    RT @cleoabram: To try to live longer, billionaires are taking a pill that costs pennies. So, uh… does it work?
    view full post

    February 1, 2022

    10

  • Cleo Abram
    @cleoabram (Twitter)

    There is some evidence that metformin helps do this in people with diabetes. In the video, we walk through the study that got Dr. Barzilai interested. BUT it's not clear that the whole "dying less" thing applies equally to people without diabetes. https://t.co/QMVEDN6PjB
    view full post

    February 1, 2022

    5

  • Cleo Abram
    @cleoabram (Twitter)

    To try to live longer, billionaires are taking a pill that costs pennies. So, uh… does it work?
    view full post

    February 1, 2022

    111

    10

  • TY (タイ)
    @150made (Twitter)

    https://t.co/nUu0AVdwUv ①糖尿病患者でメタホルン摂取グループ VS ②糖尿病でなく、メタホルンも摂取していないグループ ②のグループは糖尿病でないにもかかわらず、ライフスパン(寿命)は①のグループに比べて15%も短かった https://t.co/cXv4QXo0gS
    view full post

    July 14, 2021

    20

  • Paul Benavidez
    @paulmbenavidez (Twitter)

    Hacking the 3 Pathways of Aging https://t.co/6TL8fLPafi via @YouTube
    view full post

    July 7, 2021

  • lisa champion
    @lm_champion (Twitter)

    @naplesdave I know taking meds is a pain but there is some interest atm about met having some healthful effects other than BGL control. I have attached the Bannister paper. And the study currently looking at understanding what is going on - the TAME study.https://t.co/kVmwWHdZOC
    view full post

    June 2, 2021

    1

  • DaRocDok.com®
    @DaRocDok (Twitter)

    Hacking the 3 Pathways of Aging https://t.co/kWbfo5OujD via @YouTube
    view full post

    April 24, 2021

  • Rohit Gupta
    @rohit_bmw (Twitter)

    RT @Daniilgor: This study (published 6 years ago) strongly suggested that metformin prolongs lives. No one gave a damn. But with #COVIDー19,…
    view full post

    December 29, 2020

    1

  • Daniil Gorbatenko
    @Daniilgor (Twitter)

    This study (published 6 years ago) strongly suggested that metformin prolongs lives. No one gave a damn. But with #COVIDー19, saving the elderly suddenly became a religion. Politics is fundamentally irrational. https://t.co/BpTt3HOaG3
    view full post

    December 28, 2020

    2

    1

  • Bruno.N
    @BrunoN29428943 (Twitter)

    @drjkahn @davidasinclair Thanks for the interesting research. Mic has these notes to consider: https://t.co/ESmB4nqDJU (Includes some vegetables that naturally contain NMN).
    view full post

    December 6, 2020

    1

  • Republican-Justicialist (He/Him/The God Of F*ck)
    @JRClark14591150 (Twitter)

    https://t.co/2lH3NvvNWq
    view full post

    September 8, 2020

  • Matthew Lake
    @Matthew_Lake182 (Twitter)

    @HanCardiomd @DBelardoMD Here's the study: https://t.co/SMbbRGfCRC
    view full post

    August 27, 2020

    2

  • Matthew Lake
    @Matthew_Lake182 (Twitter)

    @und3rgrounder @DBelardoMD "Patients with type 2 diabetes initiated with metformin monotherapy had longer survival than did matched, non-diabetic controls. Those treated with sulphonylurea had markedly reduced survival" https://t.co/SMbbRGfCRC
    view full post

    August 27, 2020

  • Matthew Lake
    @Matthew_Lake182 (Twitter)

    @DBelardoMD @SteveH35081752 "Patients with T2D initiated with metformin monotherapy had longer survival than did matched, non-diabetic controls. Those treated with sulphonylurea had markedly reduced survival compared with both matched controls and....." https://t.co/SMbbRGfCRC
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    August 27, 2020

  • د هيثم السيف
    @57ksu (Twitter)

    Can people with type 2 diabetes live longer than those without? A comparison of mortality in people initiated with metformin or sulphonylurea monotherapy and matched, non‐diabetic controls https://t.co/2acmvx2SUr
    view full post

    July 27, 2020

  • ᵀᵒⁿᵉ
    @ToneLives (Twitter)

    Hacking the 3 Pathways of Aging https://t.co/bpOcwN0M4f
    view full post

    July 25, 2020

  • ~Journey P.Ⓥ︎
    @SouLJOo0oOurney (Twitter)

    Hacking the 3 Pathways of Aging https://t.co/WtyopJoBGb via @YouTube
    view full post

    July 24, 2020

  • lisa champion
    @lm_champion (Twitter)

    @bigpurpleduck @TheRhodri Metformin might help you with smoothing out the IR due to hormone stuff. It is relatively cheap and has been around for about 60 years. Also may have other protective benefits ?? (see Bannister study 2014 https://t.co/Bi6f4elpLR or TAME studyl currently going on).
    view full post

    July 2, 2020

  • Staffan
    @StaffanOlsson13 (Twitter)

    Ska metformin skrivas ut till äldre utan diabetes typ 2? https://t.co/7UxfMlKaf0
    view full post

    February 29, 2020

  • Matt Baggott
    @mattbagg (Twitter)

    @StevenSalzberg1 @EverydayFinance There is very limited evidence in diabetics, leading to efforts to study it in adults without diabetes. https://t.co/DxqBPmkfwT
    view full post

    September 17, 2019

    1

Abstract Synopsis

  • The study aimed to determine whether increased cardiovascular risk and mortality in diabetes patients was due to harmful effects of sulphonylureas or beneficial effects of metformin by comparing all-cause mortality in patients treated with either drug.
  • Researchers analyzed data from the UK Clinical Practice Research Datalink, comparing 78,241 patients on metformin, 12,222 on sulphonylureas, and 90,463 matched non-diabetic individuals over a total follow-up period of 503,384 years.
  • Findings indicated that patients on metformin had better survival rates than matched non-diabetic controls, while those on sulphonylureas faced a significant reduction in survival compared to both metformin patients and non-diabetic individuals.