PLoS One May 2015 PMID 25184294

The influence of work-related chronic stress on the regulation of emotion and on functional connectivity in the brain.

Armita Golkar, Emilia Johansson, Maki Kasahara, Walter Osika, Aleksander Perski, Ivanka Savic

Mentions

21
Peak: 4 in Jul 2022
across 8 sources since Nov 2020

Extended reach

274,939
potential audience

Total likes

7,357

Video views

267,303

Mentions per month

Nov 2020 – Aug 2025

Where it's discussed

  • X / Twitter6 posts
  • News5 articles
  • YouTube2 videos
  • Facebook2 posts
  • Instagram2 posts
  • Blogs2 articles
  • Bluesky1 posts
  • LinkedIn1 posts

AI synopsis

What people are saying

The discussions highlight the paper's focus on the impact of chronic work stress on emotion regulation and brain connectivity, with mentions of altered neural pathways and implications for mental health. Words like 'difficult to downregulate' and references to brain regions such as the amygdala and prefrontal cortex reflect a serious tone, emphasizing the importance and potential impact of the research findings.

AgreementModerate agreement

Most discussions acknowledge the findings about stress affecting emotional regulation and brain connectivity, indicating general agreement with the study's conclusions.

InterestModerate interest

Participants seem moderately interested, as they reference detailed research and suggest implications related to mental health and neuroscience.

EngagementModerate engagement

The comments demonstrate thoughtful engagement, with some posts citing specific brain regions and research details, showing deeper understanding.

ImpactModerate impact

The discussions indicate that the study may influence how we understand work-related stress, with some suggesting it could change current perceptions or practices.

Abstract in brief

  • The study investigates how chronic work-related stress (burnout) affects emotional regulation and brain connectivity, finding that stressed individuals struggle to downregulate negative emotions despite normal startle responses.
  • Brain imaging shows weakened functional connectivity between the amygdala (emotional processing center) and regions involved in regulation like the anterior cingulate cortex and dorsolateral prefrontal cortex in stressed subjects, indicating impaired emotional control.
  • Conversely, connectivity between the amygdala and areas like the cerebellum and insula is increased in stressed individuals, suggesting altered limbic network functioning that may facilitate ongoing stress and emotional dysregulation.]

Top posts

Most liked on X and Bluesky
SciComm Sadie
@Elzine21 · X

@egcartisano @AcademicChatter @CouragePhD [Functional connectivity only - No size comparisons] Golkar, Armita et al. “The influence of work-related chronic stress on the regulation of emotion and on functional connectivity in the brain.” PloS one vol. 9,9 e104550. 3 Sep. 2014, doi:10.1371/journal.pone.0104550

Jul 27, 2022 · 119 likes · 4 shares · 618 followers View post →
quantum hypescam zero
@hypescam · X

The popsci articles (eg. https://t.co/KWzHGns7dx ) cite each other, and repeat the same misreading of this paper: https://t.co/0R1cdoZ14q which doesn't measure amygdala volume and reports *decreased* functional connectivity between amygdala and PFC

Jul 27, 2022 · 1 like · 78 followers View post →
sciencenews
@Scieducation1 · X

RT @neurekaApp: Check out this paper that suggests that people exposed to #work-related chronic #stress find it more difficult to down-regu…

Nov 6, 2020 · 1 share · 5,129 followers View post →
Neureka
@neurekaApp · X

Check out this paper that suggests that people exposed to #work-related chronic #stress find it more difficult to down-regulate negative #Emotions. It may be due to altered connectivity between the amygdala and regions in frontal+limbic areas. https://t.co/9dHomQJm8V https://t.co/Mfe289s7It

Nov 6, 2020 · 1 share · 1,276 followers View post →
salma elhouri
@Selhouri · X

RT @Elzine21: @egcartisano @AcademicChatter @CouragePhD [Functional connectivity only - No size comparisons] Golkar, Armita et al. “The inf…

Jul 28, 2022 · 4 shares · 296 followers View post →
Emma
@Emma_c_smith_1 · X

RT @Elzine21: @egcartisano @AcademicChatter @CouragePhD [Functional connectivity only - No size comparisons] Golkar, Armita et al. “The inf…

Jul 28, 2022 · 4 shares · 90 followers View post →

All mentions

Parhelia
@cheetahprintcoat.bsky.social · Bluesky

anyways, if you've seen the burnout is brain damage post, here's some actual sources on what is being mentioned pubmed.ncbi.nlm.nih.gov/25184294/

Dec 16, 2024 · 1 share View post →
Emma
@Emma_c_smith_1 · X

RT @Elzine21: @egcartisano @AcademicChatter @CouragePhD [Functional connectivity only - No size comparisons] Golkar, Armita et al. “The inf…

Jul 28, 2022 · 4 shares · 90 followers View post →
salma elhouri
@Selhouri · X

RT @Elzine21: @egcartisano @AcademicChatter @CouragePhD [Functional connectivity only - No size comparisons] Golkar, Armita et al. “The inf…

Jul 28, 2022 · 4 shares · 296 followers View post →
quantum hypescam zero
@hypescam · X

The popsci articles (eg. https://t.co/KWzHGns7dx ) cite each other, and repeat the same misreading of this paper: https://t.co/0R1cdoZ14q which doesn't measure amygdala volume and reports *decreased* functional connectivity between amygdala and PFC

Jul 27, 2022 · 1 like · 78 followers View post →
SciComm Sadie
@Elzine21 · X

@egcartisano @AcademicChatter @CouragePhD [Functional connectivity only - No size comparisons] Golkar, Armita et al. “The influence of work-related chronic stress on the regulation of emotion and on functional connectivity in the brain.” PloS one vol. 9,9 e104550. 3 Sep. 2014, doi:10.1371/journal.pone.0104550

Jul 27, 2022 · 119 likes · 4 shares · 618 followers View post →
sciencenews
@Scieducation1 · X

RT @neurekaApp: Check out this paper that suggests that people exposed to #work-related chronic #stress find it more difficult to down-regu…

Nov 6, 2020 · 1 share · 5,129 followers View post →
Neureka
@neurekaApp · X

Check out this paper that suggests that people exposed to #work-related chronic #stress find it more difficult to down-regulate negative #Emotions. It may be due to altered connectivity between the amygdala and regions in frontal+limbic areas. https://t.co/9dHomQJm8V https://t.co/Mfe289s7It

Nov 6, 2020 · 1 share · 1,276 followers View post →
Verkuilen Et Al. (2020) | PDF
News

https://doi. S0140525X09991567 org/10.1371/journal.pone.0104550 16 Assessment 00(0). Halbesleben, J. R. B., & Demerouti, E. (2005). The construct validity Li ...

Dec 12, 2025 View →
Charles Stone - Holy Noticing - The Bible, Your Brain, and The ...
News

2014): e104550, https://doi.org/10.1371/journal.pone.0104550. 4. Kerry J. Ressler, “Amygdala Activity, Fear, and Anxiety: Modulation by Stress,” Biological

Dec 12, 2025 View →
Revista Universitara de Sociologie | PDF | Colonialism | Cameroon
News

https://doi.org/10.1371/journal.pone.0104550. 20. Griffin, M.L., Hogan, N.L., Lambert, E.G., Tucker-Gail, K.A., and Baker, D.N. (2009). Job Involvement, Job ...

Dec 12, 2025 View →
台大心理系系學會學術部| Taipei
Facebook

org/10.1371/journal.pone. 0104550 #工作倦怠 #你今天burnout了嗎 #台大心理系 ... International Journal of Dream Research, 10(2), 151–156. Goc, T., Krysta ...

Dec 12, 2025 View →
Tu cerebro no se quema. Se desconecta. El burnout no es solo ...
Instagram

409 likes, 119 comments - nicofernandezmiranda on August 4, 2025: "Tu cerebro no se quema. Se desconecta. El burnout no es solo cansancio…

Aug 4, 2025 View →
#brainhealth | World Health Organization | 86 comments
LinkedIn

doi:10.1371/journal.pone.0104550 #Burnout #BrainHealth #MentalHealth #WHO. Like · Reply · 15 Reactions 16 Reactions. Parkinson's Europe ...

Aug 23, 2024 View →
Want to Improve the Well-Being of Health Workers? The System ...
Blogs

https://doi.org/10.1371/journal.pone.0104550; Ridout, K.K., Ridout, S.J., et al . (2019) Physician-Training Stress and Accelerated Cellular ...

Dec 19, 2023 View →
Want To Improve The Well-Being of Health Workers - The System ...
News

https://doi.org/10.1371/journal.pone.0104550 17. Ridout, K.K., Ridout, S.J., et al . (2019) Physician-Training Stress and Accelerated ...

Dec 19, 2023 View →
This is Your Brain on Burnout — BrainPost | Easy-to-read ...
Blogs

... 10.1371/journal.pone.0104550. Jovanovic, H, Perki, A, Berglund, H, Savic, I (2011). Chronic stress is linked to 5-HT1A receptor changes in ...

Mar 28, 2023 View →
El síndrome de desgaste profesional o burnout es un estado de ...
Instagram

... Published 2014 Sep 3. doi:10.1371/journal.pone.0104550 #burnout #depre #md #medicine #reelvideo #reelviral #medicos".

Mar 10, 2023 View →
Integrating Organizational Actions Toward Patient Safety & Clinician ...
News

doi:10.1371/journal.pone.0104550. Ridout KK, Ridout SJ, et al. Physician Training Stress and Accelerated Cellular Aging. Biological ...

Jul 15, 2021 View →
文/ 維萱想必經歷過期中地獄的你各位都一定感受過全身心投注在課業 ...
Facebook

... 10.1371/journal.pone.0104550 ------------------------------ #工作倦怠#你今天burnout了嗎#台大心理系學術部#NTUPSYAD #睡死在旁編| Facebook. Log in ...

Dec 15, 2020 View →