PubHawk
JACC Heart Fail December 2014 PMID 25282031

The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.

Svend A Mortensen, Franklin Rosenfeldt, Adarsh Kumar, Peter Dolliner, Krzysztof J Filipiak, Daniel Pella, Urban Alehagen, Günter Steurer, Gian P Littarru

Download social card

Mentions

76
Peak: 5 in Aug 2025
across 7 sources since Aug 2020

Extended reach

188,379
potential audience

Total likes

836

Video views

32,832

Mentions per month

Aug 2020 – Aug 2025

Where it's discussed

  • News26 articles
  • Facebook21 posts
  • X / Twitter18 posts
  • Blogs6 articles
  • YouTube2 videos
  • Reddit2 posts
  • Bluesky1 posts

AI synopsis

What people are saying

The overall tone demonstrates strong support for the study's findings, with users highlighting impressive statistics such as a 42.3% reduction in major cardiovascular events and mentioning the drug's potential to influence treatment standards. Words like 'proven,' 'effective,' and questions like 'why don't all doctors prescribe CoQ10' reflect high interest and a belief in its significance, indicating these discussions could impact future medical approaches.

AgreementModerate agreement

Most discussions endorse the positive findings of the study, highlighting significant reductions in cardiovascular events and mortality, which shows general support for the results.

InterestHigh interest

Many posts delve into detailed results, mentioning specific percentages and the potential of CoQ10 as an effective treatment, reflecting high curiosity and interest.

EngagementHigh engagement

Conversations include references to scientific studies, comparisons, and questions about clinical practices, indicating deep involvement with the topic.

ImpactHigh impact

Posts suggest the study could influence medical practice and future research, emphasizing that CoQ10 might be undervalued or overlooked despite promising evidence.

Abstract in brief

  • This study investigated whether adding coenzyme Q10 (CoQ10) to standard treatment helps people with chronic heart failure (HF).
  • The results showed that long-term CoQ10 use reduced major heart-related problems and deaths, improved symptoms, and was safe over two years.
  • However, short-term improvements were not significant, but patients taking CoQ10 had notably fewer hospital visits and lower rates of death from cardiovascular issues and overall causes.]
Read the full abstract

Top posts

Most liked on X and Bluesky
L ❤ V E
@drkohilathas · X

CoQ10 has also been shown to help patients with chronic heart failure, improving symptoms and reducing major cardiovascular events. https://t.co/M6h9nszUTg

Mar 27, 2023 · 35 likes · 5 shares · 47,921 followers View post →
Greg Mushen
@gregmushen · X

Here is one for starters: - Major adverse cardiovascular events: 42.3% reduction (26% to 15%) - Cardiovascular mortality: 43.8% reduction (16% to 9%) - All-cause mortality: 44.4% reduction (18% to 10%). https://t.co/EYkBgrf3ra https://t.co/Q1madzyxzz

Jul 4, 2024 · 15 likes · 1 share · 30,377 followers View post →
KagawaECG
@KagawaECG · X

▶️ 慢性心不全とCoenzyme Q10について 二重盲検のランダム化比較試験 Fig2にサブグループ解析も載っていました _φ(･_･ The Effect of Coenzyme Q10 on Morbidity and Mortality in Chronic Heart... https://t.co/u5ibYhy3eF

Feb 23, 2024 · 13 likes · 1 share · 12,469 followers View post →
Reiner 
@erlesen · X

The Effect of Coenzyme Q10 on Morbidity and Mortality in Chronic Heart Failure (2014) https://t.co/jiZHMNtXEu Patients with moderate to severe HF were randomly assigned in a 2-year prospective trial to either CoQ10 100 mg 3 times daily or placebo, in addition to standard therapy

Aug 3, 2025 · 4 likes · 2 shares · 7,856 followers View post →
Will Watson
@DrWillWatson · X

@drjohnm Thanks for the RT! Time will tell; there are basic science links between ketones and cardiac fibrosis https://t.co/kiCXz7bozD ...and don't forget that the only proven metabolic treatment, Coenzyme-Q10, failed to enter mainstream despite a positive study https://t.co/QtWjMUx72u

Mar 27, 2024 · 3 likes · 3,316 followers View post →
sales_un
@sales_un · X

@masonbrown1788 @mirandadevine Why don't all doctors prescribe CO-Q10 for heart failure? It is the most effective medication according to this trial https://t.co/ldQvv1xVWV

Aug 11, 2020 · 2 likes · 646 followers View post →

All mentions

Reiner 
@erlesen · X

RT @erlesen: The Effect of Coenzyme Q10 on Morbidity and Mortality in Chronic Heart Failure (2014) https://t.co/jiZHMNtXEu Patients with mo…

Aug 5, 2025 · 2 shares · 7,856 followers View post →
Dr Richard Palmquist
@DrRPalmquist · X

RT @erlesen: The Effect of Coenzyme Q10 on Morbidity and Mortality in Chronic Heart Failure (2014) https://t.co/jiZHMNtXEu Patients with mo…

Aug 3, 2025 · 2 shares · 4,743 followers View post →
Reiner
@erlangen.bsky.social · Bluesky

The Effect of Coenzyme Q10 on Morbidity and Mortality in Chronic Heart Failure (2014) www.sciencedirect.com/science/arti... Patients with moderate to severe HF were randomly assigned in a 2-year prospective trial to either CoQ10 100 mg 3 times daily or placebo, in addition to standard therapy

Aug 3, 2025 · 1 like View post →
Reiner 
@erlesen · X

The Effect of Coenzyme Q10 on Morbidity and Mortality in Chronic Heart Failure (2014) https://t.co/jiZHMNtXEu Patients with moderate to severe HF were randomly assigned in a 2-year prospective trial to either CoQ10 100 mg 3 times daily or placebo, in addition to standard therapy

Aug 3, 2025 · 4 likes · 2 shares · 7,856 followers View post →
Richard
@PGC1a_RB · X

RT @gregmushen: Here is one for starters: - Major adverse cardiovascular events: 42.3% reduction (26% to 15%) - Cardiovascular mortality:…

Jul 4, 2024 · 1 share · 14,945 followers View post →
Greg Mushen
@gregmushen · X

Here is one for starters: - Major adverse cardiovascular events: 42.3% reduction (26% to 15%) - Cardiovascular mortality: 43.8% reduction (16% to 9%) - All-cause mortality: 44.4% reduction (18% to 10%). https://t.co/EYkBgrf3ra https://t.co/Q1madzyxzz

Jul 4, 2024 · 15 likes · 1 share · 30,377 followers View post →
Will Watson
@DrWillWatson · X

@drjohnm Thanks for the RT! Time will tell; there are basic science links between ketones and cardiac fibrosis https://t.co/kiCXz7bozD ...and don't forget that the only proven metabolic treatment, Coenzyme-Q10, failed to enter mainstream despite a positive study https://t.co/QtWjMUx72u

Mar 27, 2024 · 3 likes · 3,316 followers View post →
おれんじ色
@orangeiro7 · X

RT @KagawaECG: ▶️ 慢性心不全とCoenzyme Q10について 二重盲検のランダム化比較試験 Fig2にサブグループ解析も載っていました _φ(･_･ The Effect of Coenzyme Q10 on Morbidity and Mortali…

Feb 24, 2024 · 1 share · 1,864 followers View post →
KagawaECG
@KagawaECG · X

▶️ 慢性心不全とCoenzyme Q10について 二重盲検のランダム化比較試験 Fig2にサブグループ解析も載っていました _φ(･_･ The Effect of Coenzyme Q10 on Morbidity and Mortality in Chronic Heart... https://t.co/u5ibYhy3eF

Feb 23, 2024 · 13 likes · 1 share · 12,469 followers View post →
n
@noboobu · X

心不全患者のQ10摂取で、罹患率や死亡率が低下したとの報告 Mortensen SA, Rosenfeldt F, Kumar A, et al. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial. JACC Heart Fail. 2014;2(6):641-649.

Apr 20, 2023 · 593 followers View post →
Patricia
@plivestrong · X

RT @drkohilathas: CoQ10 has also been shown to help patients with chronic heart failure, improving symptoms and reducing major cardiovascul…

Mar 28, 2023 · 5 shares · 2,260 followers View post →
அழகரசன்
@KidambiGm · X

RT @drkohilathas: CoQ10 has also been shown to help patients with chronic heart failure, improving symptoms and reducing major cardiovascul…

Mar 27, 2023 · 5 shares · 2,177 followers View post →
diana flores
@dianaflores37 · X

RT @drkohilathas: CoQ10 has also been shown to help patients with chronic heart failure, improving symptoms and reducing major cardiovascul…

Mar 27, 2023 · 5 shares · 344 followers View post →
L ❤ V E
@drkohilathas · X

CoQ10 has also been shown to help patients with chronic heart failure, improving symptoms and reducing major cardiovascular events. https://t.co/M6h9nszUTg

Mar 27, 2023 · 35 likes · 5 shares · 47,921 followers View post →
HealthyChimp
@HealthyChimp · X

CoQ10 - Essential cofactor for energy production - Treat heart conditions and heart failure - Key nutrient to mitochondria https://t.co/5w9IJdBUIE

Jan 5, 2023 · 20 followers View post →
Peter Voshol
@Peter_Voshol · X

RT @DennisZeilstra: @FaberDietetiek Tip: maak ook onderscheid tussen ubiquinon en ubiquinol. Laatstgenoemde is de gereduceerde vorm (en duu…

Dec 23, 2020 · 1 share · 1,922 followers View post →
Dennis Zeilstra
@DennisZeilstra · X

@FaberDietetiek Tip: maak ook onderscheid tussen ubiquinon en ubiquinol. Laatstgenoemde is de gereduceerde vorm (en duurder, maar lagere dosis volstaat). Ook interessant om ff te bekijken, de Q-Symbio studie, een relatief grote en lange studie bij hartfalen: https://t.co/A4iT6jdYxB

Dec 23, 2020 · 1 like · 1 share · 2,035 followers View post →
Profe Claudio Nieto
@profeclaudioni1 · X

…. Y es que podemos ver beneficios demostrados sobre… 1 Problemas cardiovasculares https://t.co/lyZL4BQKBi

Nov 2, 2020 · 1 like · 14,139 followers View post →
sales_un
@sales_un · X

@masonbrown1788 @mirandadevine Why don't all doctors prescribe CO-Q10 for heart failure? It is the most effective medication according to this trial https://t.co/ldQvv1xVWV

Aug 11, 2020 · 2 likes · 646 followers View post →