Molecules December 2014 PMID 25474287

Curcumin and chronic kidney disease (CKD): major mode of action through stimulating endogenous intestinal alkaline phosphatase.

Siddhartha S Ghosh, Todd W B Gehr, Shobha Ghosh

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Mentions

Peak: 1 in Oct 2019

across 4 sources since Oct 2019

Extended reach

82,952

potential audience

Total likes

1,297

Video views

82,044

Mentions per month

Oct 2019 – Nov 2022

Where it's discussed

Facebook9 posts
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YouTube3 videos
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AI synopsis

What people are saying

Several discussions mention the biological mechanisms, such as curcumin stimulating intestinal enzymes, indicating scientific interest, while some posts contain exaggerated claims like 'turmeric can cure kidney disease,' which suggest varying levels of skepticism or enthusiasm; the tone varies from cautious to highly optimistic, showing an overall tentative engagement with the research.

AgreementNeither agree nor disagree

Posts show mixed reactions, with some supporting the potential benefits of curcumin, while others remain skeptical or dismissive.

InterestModerate interest

There is a moderate level of curiosity, as some discussions highlight the therapeutic potential and biological mechanisms, but others show little enthusiasm.

EngagementModerate engagement

The posts include references to scientific mechanisms and claims, indicating ongoing engagement, though some are brief or dismissive.

ImpactNeutral impact

Overall, the discussions reflect curiosity but not a definitive shift in opinion or strong influence in the field yet.

Abstract in brief

Curcumin, found in turmeric, has anti-inflammatory properties that can help combat chronic kidney disease (CKD) by reducing inflammatory molecules and improving intestinal health.
In CKD and related diseases like diabetes and cardiovascular disorders, increased gut permeability allows proinflammatory substances to enter the bloodstream, which curcumin can counteract by increasing intestinal alkaline phosphatase (IAP) and tight junction proteins.
By improving gut barrier function and reducing circulating inflammatory molecules, curcumin may have beneficial effects on CKD despite its poor bioavailability.]

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