Rejuvenation Res April 2015 PMID 25546413

Practicality of intermittent fasting in humans and its effect on oxidative stress and genes related to aging and metabolism.

Martin P Wegman, Michael H Guo, Douglas M Bennion, Meena N Shankar, Stephen M Chrzanowski, Leslie A Goldberg, Jinze Xu, Tiffany A Williams, Xiaomin Lu, Stephen I Hsu, Stephen D Anton, Christiaan Leeuwenburgh, Mark L Brantly

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Mentions

121
Peak: 2 in Apr 2020
across 6 sources since Aug 2018

Extended reach

3,168,351
potential audience

Total likes

71,620

Video views

3,155,576

Mentions per month

Aug 2018 – Apr 2023

Where it's discussed

  • News76 articles
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  • Blogs10 articles
  • X / Twitter5 posts
  • YouTube2 videos
  • Reddit2 posts

AI synopsis

What people are saying

The discussions mention the role of sirtuins and caloric restriction strategies, as in posts referencing 'Calorie Restriction During The Ramadan' and the regulation of genes like SIRT3, reflecting a basic understanding of the scientific concepts. Their tone is informational but lacks urgency or strong opinion, aligning with moderate scores for engagement and impact.

AgreementModerate agreement

Most participants seem to agree that the research offers relevant insights into intermittent fasting and its genetic effects, though not all fully endorse the conclusions, showing some nuance in opinions.

InterestModerate interest

Posts indicate a moderate level of interest, with references to specific genes like sirtuins and discussions on caloric restriction, but they don't exhibit high enthusiasm or curiosity.

EngagementNeutral engagement

The engagement appears superficial, with some discussion on related topics like calorie restriction during Ramadan, but there is little deep analysis or debate about the study's broader implications.

ImpactNeutral impact

The discussions seem to focus on general concepts and related practices rather than highlighting a transformative impact of the findings, suggesting a minor perceived influence.

Abstract in brief

  • The study explored intermittent fasting (IF) as a sustainable alternative to caloric restriction, aiming to boost genes linked to aging and reduce oxidative stress, but results showed only a slight increase in one gene (SIRT3) and no significant change in others.
  • Participants tolerated the IF diet well without adverse effects, and it led to a notable reduction in plasma insulin levels, which is beneficial for metabolic health.
  • The researchers also tested whether antioxidants (vitamins C and E) would influence these effects, but found that the diet's impact on gene expression and oxidative stress was minimal and requires further investigation.

Top posts

Most liked on X and Bluesky
عارف گرگانی
@aref_313 · X

10_)

Apr 24, 2020 · 3 likes · 5,466 followers View post →
عارف گرگانی
@aref_313 · X

8_) [7][8][9][10][11]sirtuins function... https://t.co/Rq1w4Jw7mF Calorie Restriction During The Ramadan https://t.co/6f5s4JXweD Caloric restriction...up-regulate sirtuins https://t.co/fHLdgXIOcs

Apr 24, 2020 · 2 likes · 5,466 followers View post →
مهرداد طارقُلی
@mehrdadtargholi · X

@usiriss ♦️پیشگیری و درمان سرطان

Apr 4, 2023 · 2 likes · 1,147 followers View post →
(ANU❤️)TFLU2))
@anu2121212121 · X

Practicality of Intermittent Fasting in Humans and its Effect on Oxidative Stress and Genes Related to Aging and Metabolism https://t.co/R059kHjIiv

Dec 11, 2020 · 508 followers View post →

All mentions

مهرداد طارقُلی
@mehrdadtargholi · X

@usiriss ♦️پیشگیری و درمان سرطان

Apr 4, 2023 · 2 likes · 1,147 followers View post →
(ANU❤️)TFLU2))
@anu2121212121 · X

Practicality of Intermittent Fasting in Humans and its Effect on Oxidative Stress and Genes Related to Aging and Metabolism https://t.co/R059kHjIiv

Dec 11, 2020 · 508 followers View post →
tokatti
@tokatti_ · X

フロリダ大学の実験 ヒトに対する「プチ断食」のアンチエイジング効果が確認された https://t.co/2HJcBYIlWp #自分用メモ

Jun 2, 2020 · 189 followers View post →
عارف گرگانی
@aref_313 · X

10_)

Apr 24, 2020 · 3 likes · 5,466 followers View post →
عارف گرگانی
@aref_313 · X

8_) [7][8][9][10][11]sirtuins function... https://t.co/Rq1w4Jw7mF Calorie Restriction During The Ramadan https://t.co/6f5s4JXweD Caloric restriction...up-regulate sirtuins https://t.co/fHLdgXIOcs

Apr 24, 2020 · 2 likes · 5,466 followers View post →