Obes Rev February 2015 PMID 25614201

How dieting makes the lean fatter: from a perspective of body composition autoregulation through adipostats and proteinstats awaiting discovery.

A G Dulloo, J Jacquet, J-P Montani, Y Schutz

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Mentions

58
Peak: 3 in Mar 2025
across 5 sources since May 2020

Extended reach

118,539
potential audience

Total likes

2,708

Video views

56,814

Mentions per month

May 2020 – Aug 2025

Where it's discussed

  • News28 articles
  • X / Twitter11 posts
  • Facebook10 posts
  • YouTube5 videos
  • Blogs4 articles

AI synopsis

What people are saying

Many discussions critique conventional dieting methods, emphasizing biological feedback mechanisms with phrases like 'metabolism re-sets' and 'body senses oncoming damage,' reflecting deep engagement. Users explore implications from specific terms like 'Proteinostato' and question diet efficacy, highlighting both curiosity and skepticism toward traditional approaches and emphasizing the potential for scientific breakthroughs to change perceptions.

AgreementLow agreement

Most posts strongly challenge or dismiss traditional dieting ideas, suggesting disagreement with common beliefs about weight loss and metabolism.

InterestHigh interest

Discussions show high curiosity about body regulation, theories like proteinstats, and the implications of the research, indicating high interest.

EngagementModerate engagement

Users reference complex concepts like adipostats, proteinstats, and physiological feedback, demonstrating active engagement and deep understanding.

ImpactNeutral impact

The discussions raise awareness about biological mechanisms influencing dieting outcomes but do not seem to drive immediate widespread change or policy impact.

Abstract in brief

  • Dieting may actually cause lean individuals to regain more fat than they lost due to biological feedback mechanisms involving adipostats and proteinstats, which regulate energy intake and thermogenesis during recovery.
  • When body fat and FFM (fat-free mass) are depleted through dieting, signals from these "stats" lead to increased hunger and energy expenditure adjustments, often resulting in faster fat regain (catch-up fat) compared to FFM recovery.
  • This process creates a state of persistent hunger (hyperphagia) even after fat mass is restored, and the eventual re-establishment of FFM is accompanied by continued fat deposition, contributing to the risk of becoming fatter after dieting.]

Top posts

Most liked on X and Bluesky
シュナ
@chounamoul · X

食べないダイエットやると体重すぐ減るけど、食べる量を戻した途端に元の体重に戻るだけでなく、以前よりちょっと増えた値に落ち着くんだよね。いちど飢餓を経験した体が、次の飢餓を警戒して、より多く脂肪を貯めこむように設定を変更するらしい。(Dulloo et al, 2015) https://t.co/WpXiZzPwsT

Jul 3, 2024 · 23 likes · 1 share · 33,762 followers View post →
Profe Claudio Nieto
@profeclaudioni1 · X

https://t.co/E1BWuFWQ4p Preparando el próximo vídeo para el canal, hablaremos del Proteinostato... lo que más me gusta de hacer los vídeos es que estoy aprendiendo más que nunca...

Dec 7, 2020 · 9 likes · 13,995 followers View post →
Mike Fave
@MikeFaveScience · X

Sources: https://t.co/7u8BrKXZiQ https://t.co/KxetSOiSXT https://t.co/XIexWzv2m8 https://t.co/3K49WMMSJz https://t.co/Qcl3rXWsJ3 https://t.co/enreX0yY6I

Mar 21, 2025 · 4 likes · 1,621 followers View post →
Jared Polowick
@jaredpolowick · X

@CatenaccioNA @bengreenfield Lean mass loss includes organs, which is why yo-yo dieting never works. The body slows metabolism before the point of organ damage. https://t.co/6OlIRhua6v

Jun 15, 2020 · 2 likes · 2,608 followers View post →
Mikki Williden PhD
@MikkiWilliden · X

How dieting makes the lean fatter: from a perspective of body composition autoregulation through adipostats and pro… https://t.co/bvx3mfpRMW

Aug 16, 2023 · 1 like · 2,241 followers View post →
Jared Polowick
@jaredpolowick · X

@MathieuChiasson Calorie and protein restriction shrinks muscles and organs—the body senses oncoming permanent damage and makes extreme changes. Couple good reads: https://t.co/1atZIjRvcK https://t.co/6OlIRhua6v

Sep 21, 2020 · 2,608 followers View post →

All mentions

How Dieting Can Lead to Increased Long-Term Fat Gain

This video explores how repeated dieting cycles may result in greater fat regain due to biological feedback mechanisms involving adipostats and proteinstats, which regulate energy intake and thermogenesis, ultimately…

Mike Fave · Mar 21, 2025 2,433 views

Understanding Skinny Fat and TOFI Risks and Causes

Schlanke individuals with high body fat and metabolic issues are often misunderstood. This video explores what Skinny Fat and TOFI mean, how to identify them, their health risks, and effective strategies to address…

Satte Sache · May 13, 2021 2,007 views
Mike Fave
@MikeFaveScience · X

Sources: https://t.co/7u8BrKXZiQ https://t.co/KxetSOiSXT https://t.co/XIexWzv2m8 https://t.co/3K49WMMSJz https://t.co/Qcl3rXWsJ3 https://t.co/enreX0yY6I

Mar 21, 2025 · 4 likes · 1,621 followers View post →
れんか
@yoshnoiz · X

RT @chounamoul: 食べないダイエットやると体重すぐ減るけど、食べる量を戻した途端に元の体重に戻るだけでなく、以前よりちょっと増えた値に落ち着くんだよね。いちど飢餓を経験した体が、次の飢餓を警戒して、より多く脂肪を貯めこむように設定を変更するらしい。(Dulloo…

Jul 3, 2024 · 1 share · 2,002 followers View post →
シュナ
@chounamoul · X

食べないダイエットやると体重すぐ減るけど、食べる量を戻した途端に元の体重に戻るだけでなく、以前よりちょっと増えた値に落ち着くんだよね。いちど飢餓を経験した体が、次の飢餓を警戒して、より多く脂肪を貯めこむように設定を変更するらしい。(Dulloo et al, 2015) https://t.co/WpXiZzPwsT

Jul 3, 2024 · 23 likes · 1 share · 33,762 followers View post →
Mikki Williden PhD
@MikkiWilliden · X

How dieting makes the lean fatter: from a perspective of body composition autoregulation through adipostats and pro… https://t.co/bvx3mfpRMW

Aug 16, 2023 · 1 like · 2,241 followers View post →
Leave it to Beaver
@espacetimeNOT · X

forgive me if some of my post are old. I have to re-coup my prior research as I lost access to 16 gig of data from 2020.....my MAC overwrote the operating system of a lexar. https://t.co/ebzOKyLsQK https://t.co/bKl4RUGPB8

Jan 22, 2023 · 1,199 followers View post →
Leave it to Beaver
@espacetimeNOT · X

this was suggested via a link when I looked at the meta analysis posted today. we do NOT understand why the metabolism re-sets to help us gain back our lost weight.... It may not be just "needs diet education". https://t.co/ebzOKyLsQK

Jan 22, 2023 · 1,199 followers View post →
ANorris
@andrewhnorris · X

@AdamPrihoda @tobiasdupree @wil_da_beast630 Current science. I used to believe what you think. Fact is diets are making people fatter. https://t.co/XgdRtkKs4P

Oct 18, 2022 · 49 followers View post →
Profe Claudio Nieto
@profeclaudioni1 · X

https://t.co/E1BWuFWQ4p Preparando el próximo vídeo para el canal, hablaremos del Proteinostato... lo que más me gusta de hacer los vídeos es que estoy aprendiendo más que nunca...

Dec 7, 2020 · 9 likes · 13,995 followers View post →
Jared Polowick
@jaredpolowick · X

@MathieuChiasson Calorie and protein restriction shrinks muscles and organs—the body senses oncoming permanent damage and makes extreme changes. Couple good reads: https://t.co/1atZIjRvcK https://t.co/6OlIRhua6v

Sep 21, 2020 · 2,608 followers View post →
Jared Polowick
@jaredpolowick · X

@CatenaccioNA @bengreenfield Lean mass loss includes organs, which is why yo-yo dieting never works. The body slows metabolism before the point of organ damage. https://t.co/6OlIRhua6v

Jun 15, 2020 · 2 likes · 2,608 followers View post →
Beck ||
@muffinsplanned · X

@tj_hughes15 @bigglassass @IamRouvafe @superbeesFC and if you subscribe that being overweight = unhealthy then https://t.co/mSEhpET7hq

May 8, 2020 · 438 followers View post →